Early-life exposure to endocrine disrupting chemicals associates with childhood obesity
| العنوان: | Early-life exposure to endocrine disrupting chemicals associates with childhood obesity |
|---|---|
| المؤلفون: | Zongwei Cai, Lee Ling Lim, Chunxue Yang, Arthur C.K. Chung, Hin Kiu Lee, Alice P.S. Kong |
| المصدر: | Annals of Pediatric Endocrinology & Metabolism Annals of Pediatric Endocrinology & Metabolism, Vol 23, Iss 4, Pp 182-195 (2018) |
| بيانات النشر: | Korean Society of Pediatric Endocrinology, 2018. |
| سنة النشر: | 2018 |
| مصطلحات موضوعية: | 0301 basic medicine, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Early-life exposure, Review Article, 010501 environmental sciences, 01 natural sciences, Childhood obesity, 03 medical and health sciences, Polybrominated diphenyl ethers, Environmental health, Epidemiology, medicine, Global health, Endocrine system, Endocrine disrupting chemicals, Public health policy, 0105 earth and related environmental sciences, Public awareness, business.industry, Persistent organic pollutants, lcsh:RJ1-570, lcsh:Pediatrics, medicine.disease, Early life, 030104 developmental biology, Pediatrics, Perinatology and Child Health, business |
| الوصف: | Increasing prevalence of childhood obesity poses threats to the global health burden. Because this rising prevalence cannot be fully explained by traditional risk factors such as unhealthy diet and physical inactivity, early-life exposure to endocrine disrupting chemicals (EDCs) is recognized as emerging novel risk factors for childhood obesity. EDCs can disrupt the hormone-mediated metabolic pathways, affect children’s growth and mediate the development of childhood obesity. Many organic pollutants are recently classified to be EDCs. In this review, we summarized the epidemiological and laboratory evidence related to EDCs and childhood obesity, and discussed the possible mechanisms underpinning childhood obesity and early-life exposure to non-persistent organic pollutants (phthalates, bisphenol A, triclosan) and persistent organic pollutants (dichlorodiphenyltrichloroethane, polychlorinated biphenyls, polybrominated diphenyl ethers, per- and polyfluoroalkyl substances). Understanding the relationship between EDCs and childhood obesity helps to raise public awareness and formulate public health policy to protect the youth from exposure to the harmful effects of EDCs. |
| تدمد: | 2287-1292 2287-1012 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4bb48dac5d4bf13aef15a7e05693cf3Test https://doi.org/10.6065/apem.2018.23.4.182Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....b4bb48dac5d4bf13aef15a7e05693cf3 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 22871292 22871012 |
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