Role of F-18 FDG PET/CT in assessing bone marrow involvement in pediatric Hodgkin’s lymphoma
| العنوان: | Role of F-18 FDG PET/CT in assessing bone marrow involvement in pediatric Hodgkin’s lymphoma |
|---|---|
| المؤلفون: | Bhagwant Rai Mittal, Deepak Bansal, Kuruva Manohar, Kanhaiyalal Agrawal, Raghava Kashyap, Anish Bhattacharya, Radhika Srinivasan, Neelam Varma, Amita Trehan, Ram Kumar Marwaha |
| المصدر: | Annals of Nuclear Medicine. 27:146-151 |
| بيانات النشر: | Springer Science and Business Media LLC, 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Adolescent, Multimodal Imaging, Bone Marrow, Fluorodeoxyglucose F18, Biopsy, medicine, Humans, Radiology, Nuclear Medicine and imaging, Child, Neoplasm Staging, Retrospective Studies, PET-CT, medicine.diagnostic_test, business.industry, Retrospective cohort study, General Medicine, medicine.disease, Hodgkin Disease, F 18 fdg pet ct, Pediatric Hodgkin's Lymphoma, Lymphoma, medicine.anatomical_structure, Positron emission tomography, Child, Preschool, Positron-Emission Tomography, Female, Bone marrow, Radiology, Tomography, X-Ray Computed, business, Nuclear medicine |
| الوصف: | The aim of the current study was to assess the utility of F-18-fluoro-2-deoxy-d-glucose (F-18 FDG) positron emission tomography/computed tomography (PET/CT) in assessing bone marrow involvement (BMI) compared to bone marrow biopsy (BMB) in initial staging of Hodgkin’s lymphoma (HL) in pediatric patients. Data of 38 pediatric patients (mean age 9.8 years, range 3–18 years) with HL were analyzed for the involvement of bone marrow. All patients underwent non-contrast F-18 FDG PET/CT study. BMB was done in 31 patients from the bilateral iliac crests. Scans were interpreted by two nuclear medicine physicians blinded to the details of BMB. Of the 31 patients who underwent BMB, 5 patients had lymphomatous involvement on BMB. PET/CT was positive in four of these five patients. In 26 patients negative on BMB, PET was negative in 23 patients and positive in 3 patients for BMI. The sensitivity and negative predictive value of F-18 FDG PET/CT was 87.5 and 96 %, respectively, for BMI. F-18 FDG PET/CT can predict BMB results with high accuracy. F-18 FDG PET/CT may be used at initial staging of pediatric Hodgkin’s lymphoma as it uncovers unsuspected BMI and BMB may be omitted in patients with PET-positive BMI. |
| تدمد: | 1864-6433 0914-7187 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878f3d702d5d026786c6961bd017303dTest https://doi.org/10.1007/s12149-012-0665-5Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....878f3d702d5d026786c6961bd017303d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 18646433 09147187 |
|---|