التفاصيل البيبلوغرافية
| العنوان: |
Outcome of in- and out-of-hospital cardiac arrest survivors with liver cirrhosis. |
| المؤلفون: |
Roedl, Kevin, Wallmüller, Christian, Drolz, Andreas, Horvatits, Thomas, Rutter, Karoline, Spiel, Alexander, Ortbauer, Julia, Stratil, Peter, Hubner, Pia, Weiser, Christoph, Motaabbed, Jasmin, Jarczak, Dominik, Herkner, Harald, Sterz, Fritz, Fuhrmann, Valentin |
| المصدر: |
Annals of Intensive Care; 10/6/2017, Vol. 7 Issue 1, p1-9, 9p |
| مصطلحات موضوعية: |
CIRRHOSIS of the liver, CARDIOPULMONARY resuscitation, HEALTH outcome assessment, CARDIAC arrest, MULTIPLE organ failure, PATIENTS, DISEASE risk factors |
| مستخلص: |
Background: Organ failure increases mortality in patients with liver cirrhosis. Data about resuscitated cardiac arrest patients with liver cirrhosis are missing. This study aims to assess aetiology, survival and functional outcome in patients after successful cardiopulmonary resuscitation (CPR) with and without liver cirrhosis. Methods: Analysis of prospectively collected cardiac arrest registry data of consecutively hospital-admitted patients following successful CPR was performed. Patient's characteristics, admission diagnosis, severity of disease, course of disease, short- and long-term mortality as well as functional outcome were assessed and compared between patients with and without cirrhosis. Results: Out of 1068 patients with successful CPR, 47 (4%) had liver cirrhosis. Acute-on-chronic liver failure (ACLF) was present in 33 (70%) of these patients on admission, and four patients developed ACLF during follow-up. Mortality at 1 year was more than threefold increased in patients with liver cirrhosis (OR 3.25; 95% CI 1.33-7.96). Liver cirrhosis was associated with impaired neurological outcome (OR for a favourable cerebral performance category: 0.13; 95% CI 0.04-0.36). None of the patients with Child-Turcotte-Pugh (CTP) C cirrhosis survived 28 days with good neurological outcome. Overall nine (19%) patients with cirrhosis survived 28 days with good neurological outcome. All patients with ACLF grade 3 died within 28 days. Conclusion: Cardiac arrest survivors with cirrhosis have worse outcome than those without. Although one quarter of patients with liver cirrhosis survived longer than 28 days after successful CPR, patients with CTP C as well as advanced ACLF did not survive 28 days with good neurological outcome. [ABSTRACT FROM AUTHOR] |
|
Copyright of Annals of Intensive Care is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Complementary Index |
Full Text Finder