Prognostic significance of systemic inflammatory markers in esophageal cancer: Systematic review and meta-analysis
| العنوان: | Prognostic significance of systemic inflammatory markers in esophageal cancer: Systematic review and meta-analysis |
|---|---|
| المؤلفون: | Hironori Tsujimoto, Yoji Kishi, Yoshihisa Yaguchi, Hideki Ueno, Yusuke Ishibashi |
| المصدر: | Annals of Gastroenterological Surgery Annals of Gastroenterological Surgery, Vol 4, Iss 1, Pp 56-63 (2020) |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | medicine.medical_specialty, Funnel plot, RD1-811, business.industry, platelet to lymphocyte ratio, Hazard ratio, Gastroenterology, Systematic Review Article, Publication bias, RC799-869, Cochrane Library, Diseases of the digestive system. Gastroenterology, Confidence interval, Internal medicine, Meta-analysis, medicine, Surgery, esophageal cancer, Neutrophil to lymphocyte ratio, Prospective cohort study, business, neutrophil to lymphocyte ratio, prognostic factor, C‐reactive protein to albumin ratio |
| الوصف: | Aim Impact of several immune‐inflammatory markers on long‐term outcome has been reported in various malignancies. The aim of the present study was to evaluate through a meta‐analysis the oncological outcome of immune‐inflammatory markers, such as neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), and C‐reactive protein to albumin ratio (CAR) in esophageal cancer. Methods A systematic electronic search for relevant studies was carried out in PubMed, Cochrane library, Embase, and Google scholar. Meta‐analysis was done using hazard ratio (HR) and 95% confidence interval (CI) as effect measures. A systematic review and meta‐analysis were undertaken according to the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses protocol. P‐values Forest plot for the association between C‐reactive protein to albumin ratio (CAR) and overall survival of patients treated by surgery for esophageal cancer. Only three studies (n = 1033 patients) evaluated prognostic value of CAR. Cut‐off value of the included studies ranged from 0.085 to 0.5 (median, 0.22). Higher CAR was strongly associated with poorer survival versus lower CAR (HR 1.88, 95% CI = 1.28‐2.77, P = .001). |
| تدمد: | 2475-0328 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c78d4b1a85364b6807d8df366b2424dTest https://pubmed.ncbi.nlm.nih.gov/32021959Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....6c78d4b1a85364b6807d8df366b2424d |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 24750328 |
|---|