New ST623 of Cryptococcus neoformans isolated from a patient with non-Hodgkin’s lymphoma in the Brazilian Amazon
| العنوان: | New ST623 of Cryptococcus neoformans isolated from a patient with non-Hodgkin’s lymphoma in the Brazilian Amazon |
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| المؤلفون: | Lucyane Mendes Silva, Guilherme Motta Antunes Ferreira, Marielle Machado Macedo, Marla Jalene Alves, Marcus V. G. Lacerda, Denise de Almeida Cristo, Roberto Alexandre Alves Barbosa Filho, William Antunes Ferreira, Maria de Nazaré Saunier, Ani Beatriz Jackisch-Matsuura, Cristina Motta Ferreira |
| المصدر: | Annals of Clinical Microbiology and Antimicrobials, Vol 19, Iss 1, Pp 1-5 (2020) Annals of Clinical Microbiology and Antimicrobials |
| بيانات النشر: | BMC, 2020. |
| سنة النشر: | 2020 |
| مصطلحات موضوعية: | Microbiology (medical), 030231 tropical medicine, lcsh:QR1-502, Context (language use), Case Report, Microbial Sensitivity Tests, Polymerase Chain Reaction, lcsh:Microbiology, lcsh:Infectious and parasitic diseases, 03 medical and health sciences, C. neorformans, 0302 clinical medicine, Fatal Outcome, Phylogenetics, Genotype, medicine, Humans, lcsh:RC109-216, Mycological Typing Techniques, Phylogeny, 030304 developmental biology, Aged, Cryptococcus neoformans, 0303 health sciences, Molecular Epidemiology, Molecular epidemiology, Phylogenetic tree, biology, Lymphoma, Non-Hodgkin, lcsh:RM1-950, General Medicine, Cryptococcosis, ST623, medicine.disease, biology.organism_classification, Virology, Non-Hodgkin disease, Non-Hodgkin's lymphoma, Infectious Diseases, lcsh:Therapeutics. Pharmacology, Brazil, Multilocus Sequence Typing, MLST |
| الوصف: | Background Cryptococcosis is a disease of wide geographic distribution. It is most critical when it affects immunocompromised patients, with AIDS, tuberculosis or other diseases that require prolonged hospitalization. Methods This study described a case report, molecular epidemiology, the phylogenetic relationship, along with antifungal susceptibility test of a new ST 623 of C. neoformans isolated in a patient with non-Hodgkin’s Lymphoma, from Manaus, Brazil. Results The new C. neoformans was susceptible to all antifungal drugs tested. Our results showed that ST623 new clone has no evident evolutionary proximity to any other ST of the VNI subtype group identified in Brazil. Conclusions In the context of phylogenetic analysis, this new genotype belongs to VNI subtype, and subsequencing complete genome studies are necessary to better understand the phylogenetic relationships amongst STs in this group. |
| اللغة: | English |
| تدمد: | 1476-0711 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8387df4337f3aebd604cc6e1c4a7733Test http://link.springer.com/article/10.1186/s12941-020-00361-3Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....d8387df4337f3aebd604cc6e1c4a7733 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14760711 |
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