Cryptococcal meningitis in HIV (AIDS) patients: A Mini Review
| العنوان: | Cryptococcal meningitis in HIV (AIDS) patients: A Mini Review |
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| المؤلفون: | Anupam Das, Pushpa Yadav, Vineeta Mittal, Tanushri Chatterji, Vivek Singh, Manodeep Sen |
| المصدر: | Annals of Applied Bio-Sciences. 4 |
| بيانات النشر: | Marwah Infotech, 2017. |
| سنة النشر: | 2017 |
| مصطلحات موضوعية: | 0106 biological sciences, Cryptococcus neoformans, Fungal meningitis, biology, business.industry, Meninges, biology.organism_classification, medicine.disease, 01 natural sciences, Virology, 0104 chemical sciences, Latex fixation test, Serology, Mycobacterium tuberculosis, 010404 medicinal & biomolecular chemistry, Anesthesiology and Pain Medicine, medicine.anatomical_structure, Acquired immunodeficiency syndrome (AIDS), Immunology, Medicine, business, Meningitis, 010606 plant biology & botany |
| الوصف: | Meningitis is a major health problem causing inflammation of the protective membranes covering the brain and spinal cord, collectively known as the meninges . Meningitis is generally caused by Meningococcus , Streptococcus pyogenes bacterial species causing bacterial meningitis: BM), Mycobacterium tuberculosis (Tubercular meningitis: TBM), Cryptococcus neoformans (fungal meningitis: CM). In recent times the CM and TBM are two most common types of chronic infectious meningitis. In adults, HIV-associated Cryptococcal meningitis has been reported in many areas of the world having high HIV seroprevalence i.e. in Sub-Saharan Africa. Cryptococcal meningitis is the fourth most commonly recognized cause of life-threatening infection among AIDS patients.Despite availability of antiretroviral therapy, the rise in rate of infections due to HIV/AIDS, suppress the cell mediated immune system and subjects are predisposed for opportunistic infections. Additionally, In AIDS patients, it is characterized by lack of meningeal signs and diminished inflammatory response. Diagnosis of CM is generally based on the collection of CSF sample and/or blood samples. Initially the CSF samples are processed for ‘gold standard’ culture methods, microscopy and India ink preparation. Serologically, Latex agglutination test (LAT) is the most commonly used for detection of Cryptococcal capsular antigen. Enzyme immunoassay (EIA) is another serological tool for detection of capsular polysaccharide antigens of C. neoformans in CSF. DOI: 10.21276/AABS.2017.1344 |
| تدمد: | 2349-6991 2455-0396 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::4069c2a0928e2b83eb5d3fc72ff60edcTest https://doi.org/10.21276/aabs.2017.1344Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi...........4069c2a0928e2b83eb5d3fc72ff60edc |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 23496991 24550396 |
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