التفاصيل البيبلوغرافية
| العنوان: |
Calcium-binding proteins expression in the septum and cingulate cortex of the adult guinea pig. |
| المؤلفون: |
Hermanowicz-Sobieraj, Beata, Bogus-Nowakowska, Krystyna, Robak, Anna |
| المصدر: |
Annals of Anatomy; Jan2018, Vol. 215, p30-39, 10p |
| مصطلحات موضوعية: |
CINGULATE cortex, CALCIUM-binding protein gene expression, IMMUNOHISTOCHEMISTRY, SEPTUM (Brain), GUINEA pigs, PHYSIOLOGY |
| مستخلص: |
For the first time this study demonstrates the distribution pattern and expression of three neuroanatomical markers: calbindin D28k (CB), calretinin (CR) and parvalbumin (PV) in topographically connected brain regions — the septum (SE) and the cingulate cortex (CC). The co-existence among calcium-binding proteins (CaBPs) was also examined. The study was conducted on the adult guinea pig with the use of immunohistochemical and molecular biological techniques. Among the studied CaBPs, which occurred in both examined brain regions at transcript and protein levels, CB was the most expressed in the SE, while CR in the CC. CR, unlike CB and PV, showed higher immunoreactivity in the superficial layers (II–III) of the CC than in the deep ones (V–VI). Most of CB and PV-positive perikarya were detected in the deep layers of the CC. Some CC neurons contained both CB and PV, suggesting cooperation between these CaBPs in the CC. Co-localization between CB and CR in the CC was not observed. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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