دورية أكاديمية

Absolute Lymphocyte Count Predicts Bypass Surgery Outcomes in Patients with Chronic Limb-Threatening Ischemia.

التفاصيل البيبلوغرافية
العنوان: Absolute Lymphocyte Count Predicts Bypass Surgery Outcomes in Patients with Chronic Limb-Threatening Ischemia.
المؤلفون: Yamamoto, Satoshi, Hashimoto, Takuya, Sano, Masaya, Kimura, Masaru, Sato, Osamu, Deguchi, Juno
المصدر: Ann Vasc Dis ; ISSN:1881-641X ; Volume:17 ; Issue:2
بيانات النشر: PubMed Central
سنة النشر: 2024
المجموعة: PubMed Central (PMC)
مصطلحات موضوعية: absolute lymphocyte count, bypass surgery, chronic limb-threatening ischemia
الوصف: Objectives: The aim of this study was to evaluate the relationship between absolute lymphocyte count (ALC) and outcomes of infrainguinal bypass surgery for chronic limb-threatening ischemia (CLTI). Methods: From 2004 to 2020, 209 limbs of 189 patients who underwent infrainguinal bypass surgery for CLTI and whose ALCs were available were included. Patients with survival >2 years and limb salvage >2 years were considered discriminant groups, and an ALC cut-off value was calculated. The relationship between preoperative ALC and outcomes was evaluated. Results: Survivorship of the higher ALC group was significantly higher than that of the lower ALC group (cut-off value 1030/μL, p = 0.0009). The limb salvage rate of the higher ALC group was significantly higher than that of the lower ALC group (cut-off value 1260/μL, p = 0.0081). In the dialysis patient group (103 limbs), the limb salvage rate of the higher ALC group was significantly higher than that of the lower ALC group (cut-off value 1170/μL, p = 0.026). ALC was independently associated with limb loss in multivariate analysis. Conclusion: ALC is promising as a predictor of outcomes after bypass surgery in CLTI. In particular, ALC is expected to be useful for limb prognosis in hemodialysis patients.
نوع الوثيقة: article in journal/newspaper
اللغة: English
العلاقة: https://doi.org/10.3400/avd.oa.23-00088Test; https://pubmed.ncbi.nlm.nih.gov/38919317Test; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11196179Test/
DOI: 10.3400/avd.oa.23-00088
الإتاحة: https://doi.org/10.3400/avd.oa.23-00088Test
https://pubmed.ncbi.nlm.nih.gov/38919317Test
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11196179Test/
حقوق: @ 2024 The Editorial Committee of Annals of Vascular Diseases.
رقم الانضمام: edsbas.1E2F09C9
قاعدة البيانات: BASE