Persistent Renal Dysfunction After Percutaneous Coronary Intervention in Patients With Acute Myocardial Infarction
| العنوان: | Persistent Renal Dysfunction After Percutaneous Coronary Intervention in Patients With Acute Myocardial Infarction |
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| المؤلفون: | Taek Jong Hong, Jinhee Ahn, Jeong Cheon Choe, Myung Ho Jeong, Kwang Soo Cha, Youngkeun Ahn, Jeong Su Kim, Jung Hyun Choi, Jun-Hyok Oh, Kook Jin Chun, Hye Won Lee, Yong Hyun Park, Han Cheol Lee, June Hong Kim, Jin Sup Park |
| المصدر: | Angiology. 68:159-167 |
| بيانات النشر: | SAGE Publications, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | medicine.medical_specialty, business.industry, Proportional hazards model, medicine.medical_treatment, Hazard ratio, Percutaneous coronary intervention, Renal function, 030204 cardiovascular system & hematology, medicine.disease, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Conventional PCI, Cohort, medicine, Cardiology, 030212 general & internal medicine, Myocardial infarction, Cardiology and Cardiovascular Medicine, business, Killip class |
| الوصف: | We determined the incidence, predictors, and outcomes of persistent renal dysfunction (PRD) following percutaneous coronary intervention (PCI) in patients with acute myocardial infarction (AMI). Among 16 264 patients enrolled in a nationwide registry, we studied patients with AMI who had their estimated glomerular filtration rate at baseline and 1 month later (n = 3606). We used multivariate regression and propensity score (PS)-matched Cox proportional hazards to evaluate the association between PRD and outcomes. Persistent renal dysfunction occurred in 1333 (37%) patients. Significant PRD contributors included old age, low body mass index (BMI), hypertension, Killip class, and the extent of vessel disease. Persistent renal dysfunction was associated with an increased 1-year major adverse cardiac events (all-cause death, myocardial infarction, or revascularization) relative to no-PRD (entire cohort: 6.2% vs 4.5%, hazard ratio[HR] 1.63, 95% confidence interval [CI] 1.18-2.25, P = .003; PS-matched cohort: 7.2% vs 4.9%, HR 1.67, 95% CI 1.08-2.58, P = .022). In conclusion, PRD occurred in approximately one-third of patients with AMI following PCI. It was associated with old age, hypertension, low BMI, initial hemodynamic instability, and extent of vessel disease and was a predictor of worse outcomes at 1 year. |
| تدمد: | 1940-1574 0003-3197 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_________::8bd7b4e0c6754af9dd372cce3d925897Test https://doi.org/10.1177/0003319716646680Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi...........8bd7b4e0c6754af9dd372cce3d925897 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 19401574 00033197 |
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