التفاصيل البيبلوغرافية
| العنوان: |
Palladium‐Catalyzed Asymmetric Hydrogenolysis of Aryl Triflates for Construction of Axially Chiral Biaryls. |
| المؤلفون: |
Li, Xiang1,2 (AUTHOR), Wang, Gao‐Wei2 (AUTHOR), Liu, Li‐Xia2 (AUTHOR), Yu, Chang‐Bin2 (AUTHOR) cbyu@dicp.ac.cn, Zhou, Yong‐Gui1,2 (AUTHOR) ygzhou@dicp.ac.cn |
| المصدر: |
Angewandte Chemie International Edition. 4/11/2023, Vol. 62 Issue 16, p1-6. 6p. |
| مصطلحات موضوعية: |
*HYDROGENOLYSIS, *ALLYLIC alkylation, *KINETIC resolution, *ALKYLATION |
| مستخلص: |
Here we report the first palladium‐catalyzed asymmetric hydrogenolysis of readily available aryl triflates via desymmetrization and kinetic resolution for facile construction of axially chiral biaryl scaffolds with excellent enantioselectivities and s selectivity factors. The axially chiral monophosphine ligands could be prepared from these chiral biaryl compounds and were further applied to palladium‐catalyzed asymmetric allylic alkylation with excellent ee values and high branched and linear ratio, which demonstrated the potential utility of this methodology. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
Academic Search Index |
