The validation of the Italian Edinburgh Cognitive and Behavioural ALS Screen (ECAS)
| العنوان: | The validation of the Italian Edinburgh Cognitive and Behavioural ALS Screen (ECAS) |
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| المؤلفون: | Sharon Abrahams, Andrea Faini, Daniela Calini, Stefano Zago, Federica Solca, Alessia Monti, Laura Carelli, Antonia Ratti, Alberto Doretti, Barbara Poletti, Nicola Ticozzi, Cinzia Tiloca, Fabiana Madotto, Vincenzo Silani, Federico Verde, Annalisa Lafronza |
| المساهمون: | Poletti, B, Solca, F, Carelli, L, Madotto, F, Lafronza, A, Faini, A, Monti, A, Zago, S, Calini, D, Tiloca, C, Doretti, A, Verde, F, Ratti, A, Ticozzi, N, Abrahams, S, Silani, V |
| المصدر: | Europe PubMed Central |
| بيانات النشر: | Informa UK Limited, 2016. |
| سنة النشر: | 2016 |
| مصطلحات موضوعية: | Male, medicine.medical_specialty, Psychometrics, Statistics as Topic, Neuropsychological Tests, behaviour change, 050105 experimental psychology, cognitive assessment, 03 medical and health sciences, Fluency, 0302 clinical medicine, medicine, Humans, 0501 psychology and cognitive sciences, In patient, Amyotrophic lateral sclerosis (ALS), Psychiatry, Aged, C9orf72 Protein, business.industry, Mental Disorders, Amyotrophic Lateral Sclerosis, 05 social sciences, Age Factors, Proteins, Reproducibility of Results, Cognition, Usability, Middle Aged, ECAS, Executive functions, Italy, Neurology, Convergent validity, Normative, Female, Neurology (clinical), Cognition Disorders, business, Psychology, 030217 neurology & neurosurgery |
| الوصف: | This study presents the Italian validation of the recently developed Edinburgh Cognitive and Behavioural ALS Screen (ECAS), a short screen for cognitive/behavioural alterations in patients with amyotrophic lateral sclerosis (ALS). We evaluated the psychometric properties of the ECAS Italian version in terms of reliability and convergent validity for both cognitive and behavioural features. Furthermore, we investigated the relationship with affective and clinical variables, in addition to ECAS usability and patients’ insight into cognitive/behaviour changes. Finally, correlations between genetic and cognitive/behavioural data were analysed. We recruited 107 patients with ALS. Normative data were collected on 248 healthy subjects. Participants were administered the ECAS and two standard cognitive screening tools (FAB, MoCA), two psychological questionnaires (BDI, STAI/Y) and an ad hoc usability questionnaire. The FBI was also carried out with caregivers. Results showed that the ECAS Italian version discriminated well between patients and controls. The most prevalent deficit occurred in executive functions and fluency. Correlations were observed between the ECAS and standard cognitive screening tools and between the ECAS carer interview and the FBI, supporting its full convergent validity. In conclusion, the ECAS Italian version provides clinicians with a rapid, feasible and sensitive tool, useful to identify different profiles of cognitive-behavioural impairment in ALS. |
| تدمد: | 2167-9223 2167-8421 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::386719a04c1be868883b1fa2a082e8beTest https://doi.org/10.1080/21678421.2016.1183679Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....386719a04c1be868883b1fa2a082e8be |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 21679223 21678421 |
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