التفاصيل البيبلوغرافية
| العنوان: |
First case of an UBQLN2 gene mutation causing frontotemporal dementia preceded by adult onset psychiatric symptoms. |
| المؤلفون: |
Raggi, Alberto1 (AUTHOR) albertoraggi@libero.it, Bartoletti-Stella, Anna2 (AUTHOR), Parchi, Piero2,3 (AUTHOR), Capellari, Sabina2,4 (AUTHOR) |
| المصدر: |
Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. Aug2020, Vol. 21 Issue 5/6, p467-469. 3p. |
| مصطلحات موضوعية: |
*GENETIC mutation, *FRONTOTEMPORAL dementia, *SYMPTOMS, *FRONTOTEMPORAL lobar degeneration, *AMYOTROPHIC lateral sclerosis, *MENTAL illness |
| مستخلص: |
Recently, mutations in genes related to frontotemporal dementia and/or amyotrophic lateral sclerosis have been described as the cause of late onset psychosis. Here, we report a 68-year-old patient, carrier of a mutation in the gene encoding ubiquilin-2 (UBQLN2), who presented adult onset psychotic manifestations followed by a dysexecutive syndrome compatible with the diagnosis of behavioral variant of frontotemporal dementia. Therefore, we suggest that variants in UBQLN2 should be sought in patients with this clinical condition preceded by psychiatric disorders. [ABSTRACT FROM AUTHOR] |
| قاعدة البيانات: |
Academic Search Index |
