دورية أكاديمية
'FMR1' CGG Repeats and Stress Influence Self-Reported Cognitive Functioning in Mothers
| العنوان: | 'FMR1' CGG Repeats and Stress Influence Self-Reported Cognitive Functioning in Mothers |
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| اللغة: | English |
| المؤلفون: | Maltman, Nell, DaWalt, Leeann Smith, Hong, Jinkuk, Baker, Mei Wang, Berry-Kravis, Elizabeth M., Brilliant, Murray H., Mailick, Marsha |
| المصدر: | American Journal on Intellectual and Developmental Disabilities. Jan 2023 128(1):1-20. |
| الإتاحة: | American Association on Intellectual and Developmental Disabilities. P.O. Box 1897, Lawrence, KS 66044-1897. Tel: 785-843-1235; Fax: 785-843-1274; e-mail: AJMR@allenpress.com; Web site: https://meridian.allenpress.com/aaiddTest |
| تمت مراجعته من قبل الزملاء: | Y |
| Page Count: | 20 |
| تاريخ النشر: | 2023 |
| نوع الوثيقة: | Journal Articles Reports - Research |
| الواصفات: | Genetics, Cognitive Ability, Executive Function, Memory, Stress Variables, Mothers, Children, Developmental Disabilities, Predictor Variables, Environmental Influences |
| DOI: | 10.1352/1944-7558-128.1.1 |
| تدمد: | 1944-7515 1944-7558 |
| مستخلص: | Variation in the "FMR1" gene may affect aspects of cognition, such as executive function and memory. Environmental factors, such as stress, may also negatively impact cognitive functioning. Participants included 1,053 mothers of children with and without developmental disabilities. Participants completed self-report measures of executive function, memory, and stress (i.e., life events, parenting status), and provided DNA to determine CGG repeat length (ranging from 7 to 192 CGGs). Stress exposure significantly predicted greater self-reported difficulties in executive function and the likelihood of memory problems. Cubic CGG effects independently predicted executive function and memory difficulties, suggesting effects of both genetic variation and environmental stress exposure on cognitive functioning. |
| Abstractor: | As Provided |
| Entry Date: | 2023 |
| رقم الانضمام: | EJ1375071 |
| قاعدة البيانات: | ERIC |
| تدمد: | 1944-7515 1944-7558 |
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| DOI: | 10.1352/1944-7558-128.1.1 |