Blood pressure oscillations impact signal-averaged sympathetic transduction of blood pressure: implications for the association with resting sympathetic outflow
| العنوان: | Blood pressure oscillations impact signal-averaged sympathetic transduction of blood pressure: implications for the association with resting sympathetic outflow |
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| المؤلفون: | Massimo Nardone, Lauro C. Vianna, André L. Teixeira, Anthony V. Incognito, Carlin Katerberg, Philip J. Millar |
| المصدر: | American Journal of Physiology-Heart and Circulatory Physiology. 321:H798-H806 |
| بيانات النشر: | American Physiological Society, 2021. |
| سنة النشر: | 2021 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Sympathetic Nervous System, Time Factors, Physiology, Rest, 030204 cardiovascular system & hematology, Cardiovascular System, Signal, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Physiology (medical), Internal medicine, Electric Impedance, medicine, Humans, Arterial Pressure, Muscle, Skeletal, Photoplethysmography, business.industry, Electrodiagnosis, Blood Pressure Determination, Blood pressure, Cardiology, Female, Sympathetic outflow, Cardiology and Cardiovascular Medicine, business, Transduction (physiology), 030217 neurology & neurosurgery |
| الوصف: | Signal-averaged sympathetic transduction of blood pressure (BP) is inversely related to resting muscle sympathetic nerve activity (MSNA) burst frequency in healthy cohorts. Whether this represents a physiological compensatory adaptation or a methodological limitation, remains unclear. The current analysis aimed to determine the contribution of methodological limitations by evaluating the dependency of MSNA transduction at different levels of absolute BP. Thirty-six healthy participants (27 ± 7 yr, 9 females) underwent resting measures of beat-to-beat heart rate, BP, and muscle sympathetic nerve activity (MSNA). Tertiles of mean arterial pressure (MAP) were computed for each participant to identify cardiac cycles occurring below, around, and above the MAP operating pressure (OP). Changes in hemodynamic variables were computed across 15 cardiac cycles within each MAP tertile to quantify sympathetic transduction. MAP increased irrespective of sympathetic activity when initiated below the OP, but with MSNA bursts provoking larger rises (3.0 ± 0.9 vs. 2.1 ± 0.7 mmHg |
| تدمد: | 1522-1539 0363-6135 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efc58669e1a67bd849acfb649e69b89eTest https://doi.org/10.1152/ajpheart.00422.2021Test |
| رقم الانضمام: | edsair.doi.dedup.....efc58669e1a67bd849acfb649e69b89e |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 15221539 03636135 |
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