المؤلفون: O'Brien, Daniel C, Robinson, Aaron D, Wang, Nancy, Diaz, Rodney

المصدر: American Journal of Otolaryngology. 40(3)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Clinical Sciences, Brain Disorders, Clinical Trials and Supportive Activities, Clinical Research, 6.1 Pharmaceuticals, Evaluation of treatments and therapeutic interventions, Adolescent, Adult, Aged, Chronic Disease, Female, Follow-Up Studies, Humans, Lidocaine, Male, Middle Aged, Pilot Projects, Prospective Studies, Time Factors, Tinnitus, Transdermal Patch, Treatment Outcome, Young Adult, Clinical trial, Otorhinolaryngology, Clinical sciences, Dentistry

الوصف: OBJECTIVE:To assess the efficacy of transdermal lidocaine as a treatment for chronic subjective tinnitus as measured by the Tinnitus Functional Index (TFI). STUDY DESIGN:Pilot, prospective efficacy trial. SETTING:Tertiary care hospital. PATIENTS:Men and women, over the age of 18 with chronic subjective tinnitus for >6 months. INTERVENTION:Daily application of commercially available transdermal lidocaine patch. OUTCOME MEASURE:Change in the TFI. RESULTS:The average pre-treatment TFI score was 56.2. After 1 month the average TFI decreased to 41 (p

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/7f13b2nxTest

المؤلفون: Moshtaghi, Omid, Haidar, Yarah M, Sahyouni, Ronald, Rajaii, Ramin, Moshtaghi, Afsheen, Mahmoodi, Amin, Ghavami, Yaser, Lin, Harrison W, Djalilian, Hamid R

المصدر: American Journal of Otolaryngology. 38(2)

مصطلحات موضوعية: Clinical Research, Management of diseases and conditions, 7.1 Individual care needs, Ambulatory Care, Case-Control Studies, Computers, Handheld, Health Knowledge, Attitudes, Practice, Humans, Otolaryngology, Patient Education as Topic, Patient education, iBook, Interactive, Understanding, Knowledge, Tinnitus, Dizziness/vertigo, Hearing loss, Cochlear implant, Clinical Sciences, Otorhinolaryngology

الوصف: IntroductionPhysicians in the ambulatory setting face challenges in adequately educating patients in a brief office encounter.ObjectiveTo evaluate the efficacy of an iPad-based interactive educational module (iBook) in various otologic pathologies.MethodsPatients presenting with symptoms of tinnitus, dizziness, hearing loss, or cochlear implant evaluation were included. In total, 44 patients received the iBook and 22 patients served as controls. Prior to viewing the iBook, patients completed a pre-survey to assess baseline knowledge. After viewing the iBook, patients completed a post-survey to assess changes in perception and knowledge of their disease. Results were compared to that of the control group who did not receive iBook supplementation prior to being seen by the physician.ResultsPaired t-test analysis showed significant improvements (p

وصف الملف: application/pdf

الوصول الحر: https://escholarship.org/uc/item/1df529jrTest

المؤلفون: Jing Lv, Xue Yang, Mingkun Han

المصدر: American journal of otolaryngology. 42(6)

مصطلحات موضوعية: Adult, Counseling, Male, medicine.medical_specialty, Cochrane Library, 03 medical and health sciences, Tinnitus, Young Adult, 0302 clinical medicine, Hearing, otorhinolaryngologic diseases, Medicine, Effective treatment, Humans, 030223 otorhinolaryngology, Music Therapy, Aged, Randomized Controlled Trials as Topic, Response rate (survey), business.industry, Middle Aged, Combined Modality Therapy, Large sample, Treatment Outcome, Otorhinolaryngology, Acoustic Stimulation, Tinnitus retraining therapy, 030220 oncology & carcinogenesis, Meta-analysis, Inclusion and exclusion criteria, Physical therapy, Quality of Life, Female, medicine.symptom, business

الوصف: To evaluate the efficacy of Tinnitus Retraining Therapy (TRT) in the treatment of tinnitus.Computer retrieval of PubMed, Embase, The Cochrane Library, Web of Science, China National Knowledge Internet (CNKI), Wanfang data, etc., were conducted. According to the inclusion and exclusion criteria, the literature's quality was evaluated, and useful data was extracted. All statistical analyses were performed by RevMan5.3 software.13 eligible RCTs with a total of 1345 patients were included in this meta-analysis. The meta-analysis results showed that the 1-month response rate, 3-month response rate, 6-month response rate, and overall response rate of TRT with drugs for tinnitus were higher than that of drugs only (P 0.05). The results demonstrated that the THI scale after the treatment period of TRT with medications for tinnitus was lower than that of drugs only (P 0.05).Analysis of limited studies low-quality evidence with a high risk of bias showed that the TRT was an effective treatment for tinnitus, which could improve the response rate of tinnitus and reduce the THI scale. However, more multicenter RCTs with a large sample number and high quality should verify the conclusion mentioned above.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f7666725f65917672d5ac046370441dTest
https://pubmed.ncbi.nlm.nih.gov/34303210Test

المؤلفون: Shujian Yu, Bo Du, Hong Yu, Xin Wang

المصدر: American journal of otolaryngology. 42(6)

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Adolescent, Visual analogue scale, Chronic tinnitus, Administration, Oral, Cochrane Library, 03 medical and health sciences, Tinnitus, Young Adult, 0302 clinical medicine, Pharmacotherapy, Oral administration, Internal medicine, otorhinolaryngologic diseases, medicine, Humans, Thiamine, 030223 otorhinolaryngology, Music Therapy, Aged, Phenylpropionates, business.industry, Lidocaine, Middle Aged, Vitamin B 12, Sound, Treatment Outcome, Otorhinolaryngology, Acoustic Stimulation, 030220 oncology & carcinogenesis, Meta-analysis, Chronic Disease, Female, Sound therapy, medicine.symptom, business

الوصف: To compare the efficacy of acoustic therapy (AT) and drug therapy (DT) for chronic tinnitus.We searched Pubmed, ScienceDirect, Chinese Journal Full-text Database (CNKI), Wanfang Database, Chinese Biomedical Literature Database (CBM), Embase, and Cochrane Library from the establishment of the database to December 2019. Meta-analysis was performed on the Tinnitus Handicap Inventory (THI) score and Visual Analogue Scale (VAS) with included literature using Revman 5.3 software.A total of 18 documents were included, including 16 Chinese documents and 2 English documents, with 1774 patients (including 962 patients treated with AT and 812 patients treated with DT). The effect of AT (by the number of cases or ears) is better than that of DT (P 0.05). After treatment, the THI value of AT was more evident than that of DT (WMD = -4.25, (-13.24, -5.29)). And the VAS value of AT was significantly lower than that of DT (WMD = -0.73, (-1.31, -0.15)).Compared with DT, AT can significantly improve the efficacy of tinnitus and reduce the symptoms of tinnitus patients. Clinically, it can vigorously promote the application value of treating tinnitus by sound.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6623d77ab2d6ef9caea963096608130Test
https://pubmed.ncbi.nlm.nih.gov/34293623Test

المؤلفون: Min Huang, Chunyan He, Yuqin Chen, Songli Xi, Juan Li, Jianhua Jin, Qian Zhu

المصدر: American Journal of Otolaryngology. 40:253-256

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Adolescent, Hydrocortisone, medicine.medical_treatment, Subjective tinnitus, Intervention group, Anxiety, behavioral disciplines and activities, Tinnitus, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Hostility, Intervention (counseling), otorhinolaryngologic diseases, medicine, Humans, Clinical efficacy, 030223 otorhinolaryngology, Aged, Aged, 80 and over, Cognitive Behavioral Therapy, Depression, business.industry, Middle Aged, medicine.disease, Treatment efficacy, Cognitive behavioral therapy, Treatment Outcome, Otorhinolaryngology, Mood disorders, 030220 oncology & carcinogenesis, Chronic Disease, Physical therapy, Interleukin-2, Female, medicine.symptom, business, Biomarkers

الوصف: Although cognitive behavioral therapy (CBT) has been known with a theoretical basis for tinnitus patients, there still were lack of clinical evidence.To evaluate the clinical efficacy of cognitive behavioral therapy (CBT) for treatment of chronic subjective tinnitus.One hundred patients with chronic subjective tinnitus patients were randomly divided into control (50 cases) and intervention (50 cases) groups, which received the masking therapy and sound treatment and masking therapy and sound treatment plus CBT. The treatment efficacy was evaluated.The total effective rate in intervention group was significantly higher than control group (P 0.01). After treatment, compared with control group, in intervention group the psychotic somatization, interpersonal sensitivity, depression, anxiety, hostility, terror, and phobic anxiety scores in Symptom Checklist-90 and Tinnitus Handicap Inventory score were significantly decreased (P 0.05), the serum cortisol level was significantly decreased (P 0.05), and the serum interleukin-2 level was significantly increased (P 0.05).Based on the elimination the mood disorders and reduce the stress, CBT can significantly relieve the symptoms of chronic subjective tinnitus.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d239fbc56890fba4c0bfa034d296541Test
https://doi.org/10.1016/j.amjoto.2018.10.017Test

المؤلفون: William L. Valentino, Brian J. McKinnon

المصدر: American Journal of Otolaryngology. 40:770-775

مصطلحات موضوعية: Male, Rhinology, Facial trauma, medicine.medical_specialty, Medical Marijuana, Subspecialty, Sleep medicine, Otolaryngology, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, 030223 otorhinolaryngology, Cannabis, Evidence-Based Medicine, biology, business.industry, biology.organism_classification, medicine.disease, United States, Obstructive sleep apnea, Treatment Outcome, Otorhinolaryngology, 030220 oncology & carcinogenesis, Family medicine, Female, medicine.symptom, business, Needs Assessment, Tinnitus

الوصف: Objectives Review of the English literature for all studies involving cannabis and Otolaryngology. Methods PubMed was searched using a combination of the terms cannabis, marijuana, otolaryngology, hearing, tinnitus, vestibular, rhinology, sinusitis, laryngology, voice, airway, head and neck, head and neck cancer, facial trauma, spasm, pediatric otolaryngology, sleep medicine, obstructive sleep apnea, and other variations. Literature included in the review provided substantive research on cannabis in Otolaryngology. Results Seventy-nine unique publications were found in the literature. The majority were published in the last decade and pertain to the subspecialty of Head and Neck; specifically, its association with incident cancers. A small number of studies exist that suggest cannabis may be a useful therapy for Otolaryngological patients suffering from blepharospasm, the effects of radiation, and the psychological sequelae of receiving a cancer diagnosis. Conclusion Further research is required to determine the potential therapeutic roles and adverse effects of cannabis on conditions related to Otolaryngology. This study serves the Otolaryngological researcher with the most current, comprehensive literature review for the exploration into possible projects to undertake.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c14260c6411f2bf76f576c0d4461901Test
https://doi.org/10.1016/j.amjoto.2019.05.025Test

المؤلفون: Michael Fook-Ho Lee, Wai Keat Wong

المصدر: American journal of otolaryngology. 43(1)

مصطلحات موضوعية: Adult, Male, Myoclonus, Pediatrics, medicine.medical_specialty, Botulinum Toxins, Adolescent, Ear, Middle, Young Adult, Medicine, Humans, Child, Ear Diseases, Aged, Palatal myoclonus, business.industry, Clinical study design, Evidence-based medicine, Middle Aged, medicine.disease, Botulinum toxin, medicine.anatomical_structure, Tenotomy, Treatment Outcome, Otorhinolaryngology, Anti-Anxiety Agents, Middle ear, Anticonvulsants, Female, medicine.symptom, business, Stepwise approach, Tinnitus, medicine.drug, Central Nervous System Agents

الوصف: Objective To perform a systematic review of the diagnosis and treatment of patients with pulsatile tinnitus secondary to middle ear myoclonus. Databases reviewed PubMed, EMBASE, and Scopus. Methods A systematic review was performed using standardized methodology. Computerized and manual searches were performed to identify studies of all ages (patients) who had middle ear myoclonus (intervention). All study designs were assessed. Extracted data included demographics, clinical features, duration of followup as well as the diagnosis and reversibility of symptoms with medical or surgical intervention. Studies were included if they included subjects with middle ear myoclonus. Exclusion criteria included letters/commentaries and reviews. Results Twenty articles representing 115 subjects with middle ear myoclonus were included. The mean age was 29.7 (range 6–67). The follow-up period ranged from 5 weeks to 36 months. Primary treatment consists of medical therapy utilising anxiolytics, antiepileptics, botulinum toxin and surgical treatment involving division of middle ear muscular tendon(s). In total, 60 patients underwent middle ear muscular tenotomies, with division of both stapedius and tensor tympani tendons being the most prevalent (88%). Limitations in the data arose from study design, related comorbidities such as palatal myoclonus, and concomitant drug administration. No study provided any objective criteria to diagnose this condition or evaluate post-treatment outcome. Conclusion Middle ear myoclonus is an entity that is poorly assessed in the literature. There is a lack of consensus regarding the criteria and strategies for both diagnosing and treating this condition. Although level of evidence of current studies remains modest, it is felt that a stepwise approach is deemed best, with therapeutic decisions being made on an individual basis, evaluating each patient's specific circumstances and priorities.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e64e94d9f0be6e4fc23681faed7cf55Test
https://pubmed.ncbi.nlm.nih.gov/34537509Test

المؤلفون: Zehra Aydoğan, Merve Cinar Satekin, Muhammed Sefa Uyar, Songül Aksoy, Suna Tokgoz-Yilmaz

المصدر: American Journal of Otolaryngology. 43:103521

مصطلحات موضوعية: Tinnitus, Treatment Outcome, Audiometry, Visual Analog Scale, Otorhinolaryngology, Quality of Life, Transcutaneous Electric Nerve Stimulation, Humans

الوصف: It is aimed to determine the therapeutic role of transcutaneous electrical nerve stimulation (TENS) on chronic subjective tinnitus with a randomized and comparative analysis.46 individuals with normal hearing, chronic subjective tinnitus, aged 20-65; randomly divided into the study (TENS therapy) and tje control groups. The control group (n = 23) was informed only about tinnitus, while the study group (n = 23) received TENS therapy (20 sessions in 4 weeks). Before TENS therapy, tinnitus-related evaluations of all participants [tinnitus frequency, loudness, minimum masking level (MMS), residual inhibition (RI)] were made and Tinnitus Handicap Inventory (THI), Visual Analogue Scale (VAS), Short Form 36 (SF-36), and The Quality of Life Scale were applied to the participants. These evaluations and questionnaires were repeated after 4 weeks of the therapy.There was a significant decrease in the tinnitus severity after TENS therapy in the study group (p = 0.003). Moreover, it was found that VAS (loudness and annoyance), THI (functional, emotional and total score), SF-36 (physical function, physical role, pain, general health, vitality, emotional role and social function) values improved compared to before TENS therapy and the difference was significant (p 0.05). There was no significant difference between the first and last evaluations of the control group (p 0.05).TENS is an effective, practical and reliable therapy method in reducing severity, loudness, and annoyance of tinnitus, and increasing the quality of life in individuals with chronic subjective tinnitus.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db626287d17eddbd7f901ea6307e0001Test
https://doi.org/10.1016/j.amjoto.2022.103521Test

المؤلفون: Giuseppe Chiarella, Davide Pisani, Michele Trimboli, Antonio Gambardella, Pasquale Viola, Antonio Secondo Fiorillo, Alfonso Scarpa, Salvatore A. Pullano

المصدر: American journal of otolaryngology (Online) 41 (2020): 102739. doi:10.1016/j.amjoto.2020.102739
info:cnr-pdr/source/autori:Viola P.; Pisani D.; Pullano S.A.; Trimboli M.; Scarpa A.; Fiorillo A.S.; Gambardella A.; Chiarella G./titolo:Objective bilateral tinnitus from palatal nystagmus. Audio and video features of a rare case of palatal myoclonus/doi:10.1016%2Fj.amjoto.2020.102739/rivista:American journal of otolaryngology (Online)/anno:2020/pagina_da:102739/pagina_a:/intervallo_pagine:102739/volume:41

مصطلحات موضوعية: Larynx, Myoclonus, medicine.medical_specialty, Sound Spectrography, Movement, Video Recording, Audiology, Nose, Tinnitus, Rare Diseases, otorhinolaryngologic diseases, Medicine, Humans, Bilateral tinnitus, Ear canal, Palatal myoclonus, Soft palate, business.industry, Middle Aged, medicine.disease, Larinx myoclonus, Objective tinnitus, Palatal Nystagmus, medicine.anatomical_structure, Otorhinolaryngology, Chronic Disease, Etiology, Female, Palatal Muscle, medicine.symptom, Palate, Soft, business, Ear Canal

الوصف: Tinnitus is one of the most represented otological symptom, affecting 15% of adults, worldwide. Literature describes subjective tinnitus when it's perceived by the patient only, and objective tinnitus when it's heard both, by patient and examiner. An objective tinnitus can be caused by a large variety of anomalies and diseases; one of them is Palatal Myoclonus, characterized by rhytmic movements of soft palatal muscles and, only occasionally, involving other near districts. Case presentation. We observed a rare case of essential palatal myoclonus in a 54 y.o. female, suffering from chronic objective bilateral tinnitus, since 35 years, who underwent a wide number of clinical evaluations over the years, without receiving any conclusive diagnosis. In this video, we illustrate all the districts involved in clonic movements: soft palate, larynx and nasal wings. At the same time, we report the spectrographic analysis of tinnitus, recorded in esternal ear canal, taken together with the muscle movements. Palatal Myoclonus has to be considered in the etiological diagnosis of each objective tinnitus and should always be investigated properly.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd74ba3576678c527d269495dff62e05Test
https://pubmed.ncbi.nlm.nih.gov/32993860Test

المؤلفون: Florian Putz, Heinrich Iro, Felix Eisenhut, Rainer Fietkau, Vivian Thimsen, Thomas Weissmann, Lava Taha, Konstantinos Mantsopoulos, Joachim Hornung

المصدر: American journal of otolaryngology. 43(1)

مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Hearing loss, medicine.medical_treatment, Skull Neoplasms, Ear, Middle, Paraganglioma, Tinnitus, Tympanoplasty, Quality of life, Temporal bone, medicine, Humans, Hearing Loss, Reduction (orthopedic surgery), Retrospective Studies, business.industry, Temporal Bone, Middle Aged, medicine.disease, Combined Modality Therapy, medicine.anatomical_structure, Treatment Outcome, Otorhinolaryngology, Middle ear, Quality of Life, Female, Radiotherapy, Adjuvant, Radiology, medicine.symptom, business, Otologic Surgical Procedures, Organ Sparing Treatments

الوصف: Introduction The aim of this study was to present our concept in the management of extracranial temporal bone paragangliomas and demonstrate the outcome after primary surgical management of the middle ear component, with an individualized indication for adjuvant radiotherapy. Materials and methods The records of all patients treated for extracranial jugulotympanic paragangliomas by means of primary surgical management between 2010 and 2021 were studied retrospectively. Results Twenty-nine patients made up our study sample (mean age 58.8 years). 15 cases were managed solely by means of surgery. Out of the remaining 14 cases with reduction of the middle ear component, adjuvant irradiation was performed in 11 cases, whereas a wait-and-scan strategy was adopted at the patient's request in three cases. No further growth was detected in our study cases. Conclusion Our protocol seems to be associated with an acceptable quality of life and a satisfactory oncologic outcome.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82c26ab6c68e776aec7064f4ae7256b5Test
https://pubmed.ncbi.nlm.nih.gov/34536923Test