التفاصيل البيبلوغرافية
| العنوان: |
Multisystem Langerhans Cell Histiocytosis: Successful Treatment with Thalidomide. |
| المؤلفون: |
Broekaert, Sigrid M. C., Metzler, Gisela, Burgdorf, Walter, Röcken, Martin, Martin Schaller |
| المصدر: |
American Journal of Clinical Dermatology; 2007, Vol. 8 Issue 5, p311-314, 4p, 3 Color Photographs |
| مصطلحات موضوعية: |
LANGERHANS-cell histiocytosis, LYMPHATIC diseases, IMMUNOHISTOCHEMISTRY, LYMPHOMAS, CLINICAL medicine research, THALIDOMIDE, DESMOPRESSIN, THERAPEUTICS |
| مستخلص: |
A 57-year-old woman presented with a 1-year history of non-healing inguinal and perianal ulcers as well as a 2-year history of polydipsia. The clinical picture and histology suggested Langerhans cell histiocytosis, which was confirmed by immunohistochemistry and electron microscopy. Magnetic resonance imaging of the brain revealed hypothalamic-pituitary axis involvement. Treatment was started with thalidomide and desmopressin. The skin lesions resolved over 2 months. Over the next 24 months of continued therapy, the cerebral involvement remained stable and the skin lesions did not recur. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
Complementary Index |
