التفاصيل البيبلوغرافية
| العنوان: |
Sirolimus-eluting and paclitaxel-eluting stents for the treatment of coronary bifurcations. |
| المؤلفون: |
Latib, Azeem, Cosgrave, John, Godino, Cosmo, Qasim, Asif, Corbett, Simon J., Tavano, Davide, Morici, Nuccia, Cristell, Nicole, Chieffo, Alaide, Carlino, Mauro, Montorfano, Matteo, Airoldi, Flavio, Colombo, Antonio |
| المصدر: |
American Heart Journal; Oct2008, Vol. 156 Issue 4, p745-750, 6p |
| مصطلحات موضوعية: |
RAPAMYCIN, PACLITAXEL, CORONARY heart disease treatment, DRUG efficacy |
| مستخلص: |
Background: The aim of the study was to compare the outcomes of sirolimus-eluting (SES) and paclitaxel-eluting (PES) stent implantation in coronary bifurcations treated with either a 1-stent or 2-stent strategy.Methods: The study used a retrospective cohort analysis of consecutive de novo bifurcations, excluding left main, treated with SES or PES between April 2003 and June 2005.Results: We identified 170 bifurcations in 161 patients treated with SES and 119 bifurcations in 112 patients treated with PES. During a median follow-up of 1,061 days (interquartile range 814-1,314), 43 patients (26.7%) in the SES group and 28 (25.0%) in the PES group had a major adverse cardiac event (P = .78). The angiographic restenosis rate per bifurcation was 20.9% and 25.9%, respectively (P = .41). There was no difference overall in the occurrence of target lesion revascularization (TLR) per bifurcation, 22 with SES (12.9%) and 18 with PES (15.1%), P = .61. The TLR rate was similar for SES and PES in bifurcations treated with 1 stent (6.7% vs 11.4%, P = .40) and in bifurcations treated with both branch stenting (20.0% vs 20.4%, P =1.0).Conclusions: In this cohort, the long-term clinical outcomes appear similar overall between SES and PES in the treatment of coronary bifurcations irrespective of whether a 1-stent or 2-stent strategy was used. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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