المؤلفون: Katherine C. Wilson, Mutsa Mhangara, Simon Gregson, Jeffrey W. Eaton, Timothy B. Hallett, Janet Dzangare, Owen Mugurungi

المساهمون: Medical Research Council (MRC), UNAIDS, National Institutes of Health

المصدر: AIDS (London, England)
S102
S95

مصطلحات موضوعية: Pediatrics, HIV Infections, 0302 clinical medicine, Pregnancy, hemic and lymphatic diseases, Epidemiology, Immunology and Allergy, Medicine, 030212 general & internal medicine, Pregnancy Complications, Infectious, POPULATION, reproductive and urinary physiology, education.field_of_study, 1. No poverty, Attendance, Prenatal Care, 11 Medical And Health Sciences, Middle Aged, Hiv prevalence, female genital diseases and pregnancy complications, 3. Good health, Infectious Diseases, Epidemiological Monitoring, Female, 0305 other medical science, Life Sciences & Biomedicine, HIV surveillance, Zimbabwe, Adult, medicine.medical_specialty, Adolescent, participation bias, prevalence, Immunology, Population, READY, Developing country, Article, 17 Psychology And Cognitive Sciences, Young Adult, 03 medical and health sciences, Virology, Environmental health, FERTILITY, Humans, education, Antenatal clinics, Science & Technology, 030505 public health, business.industry, Public health, 06 Biological Sciences, PREVENTION, TRENDS, Rural area, business, TO-CHILD TRANSMISSION, antenatal clinic bias

الوصف: Objective: The objective was to assess whether HIV prevalence measured among women attending antenatal clinics (ANCs) are representative of prevalence in the local area, or whether estimates may be biased by some women's choice to attend ANCs away from their residential location. We tested the hypothesis that HIV prevalence in towns and periurban areas is underestimated in ANC sentinel surveillance data in Zimbabwe. Methods: National unlinked anonymous HIV surveillance was conducted at 19 ANCs in Zimbabwe in 2000, 2001, 2002, 2004, 2006, 2009, and 2012. This data was used to compare HIV prevalence and nonlocal attendance levels at ANCs at city, town, periurban, and rural clinics in aggregate and also for individual ANCs. Results: In 2000, HIV prevalence at town ANCs (36.6%, 95% CI 34.4–38.9%) slightly underestimated prevalence among urban women attending these clinics (40.7%, 95% CI 37.6–43.9%). However, there was no distortion in HIV prevalence at either the aggregate clinic location or at individual clinics in more recent surveillance rounds. HIV prevalence was consistently higher in towns and periurban areas than in rural areas. Nonlocal attendance was high at town (26–39%) and periurban (53–95%) ANCs but low at city clinics (

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a602315a13c82b993e656c6734ef574Test
https://doi.org/10.1097/qad.0000000000001337Test

المؤلفون: Rosemary, Dray-Spira, Camille, Legeai, Mariette, Le Den, François, Boué, Caroline, Lascoux-Combe, Anne, Simon, Thierry, May, Cécile, Goujard, Laurence, Meyer, Isabelle, Suaud

المساهمون: Centre de recherche en épidémiologie et santé des populations (CESP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris-Sud - Paris 11 (UP11)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ), Service de médecine interne, immunologie clinique [Béclère], AP-HP - Hôpital Antoine Béclère [Clamart], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service de maladies infectieuses et tropicales [Saint-Louis], Université Paris Diderot - Paris 7 (UPD7)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service de médecine interne [CHU Pitié-Salpétrière], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Service des Maladies Infectieuses et Tropicales [CHRU Nancy], Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy), Service de médecine interne et maladies infectieuses, Hôpital Bicêtre-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris-Sud - Paris 11 (UP11), ANRS COPANA Cohort Study Group

المصدر: AIDS
AIDS, Lippincott, Williams & Wilkins, 2012, 26 (2), pp.207-15. ⟨10.1097/QAD.0b013e32834dcf61⟩

مصطلحات موضوعية: Male, Gerontology, Health Status, HIV Infections, Kaplan-Meier Estimate, Comorbidity, Cohort Studies, 0302 clinical medicine, Cost of Illness, Employment status, Immunology and Allergy, Prospective Studies, 030212 general & internal medicine, 10. No inequality, Prospective cohort study, Depression (differential diagnoses), education.field_of_study, Depression, Hazard ratio, 1. No poverty, Middle Aged, 3. Good health, Infectious Diseases, Cardiovascular Diseases, Cohort, Female, France, HIV-related discrimination, 0305 other medical science, Cohort study, Adult, Employment, Anti-HIV Agents, Immunology, Population, Socioeconomic factors, Truth Disclosure, Article, 03 medical and health sciences, Diabetes Mellitus, medicine, Humans, education, Occupational Health, Proportional Hazards Models, 030505 public health, business.industry, Proportional hazards model, medicine.disease, HIV-1, [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie, business, Demography

الوصف: International audience; OBJECTIVES: Employment status is a major predictor of health status and living conditions, especially among HIV-infected people, a predominantly working-aged population. We aimed to quantify the risk of work cessation following HIV diagnosis in France in 2004-2010 and to measure the respective burden of HIV-related characteristics and of associated comorbidities on this risk. DESIGN: We used data from a multicenter cohort made of a diversified sample of recently diagnosed HIV-1-infected adults, antiretroviral treatment-naive at baseline in 2004-2008 (ANRS-COPANA cohort). Detailed information on living conditions and clinical and biological characteristics were collected prospectively. METHODS: The risk of work cessation among the 376 working-aged participants employed at baseline was estimated using the Kaplan-Meier method. Characteristics associated with the risk of work cessation were identified using multivariate Cox models. RESULTS: The cumulative probability of work cessation reached 14.1% after 2 years and 34.7% after 5 years. Diabetes, hypertension and, to a lesser extent, signs of depression were associated with increased risks of work cessation after accounting for socio-occupational characteristics [adjusted hazard ratios (95% confidence interval): 5.7 (1.7-18.8), 3.1 (1.5-6.4) and 1.6 (0.9-2.9), respectively]. In contrast, HIV disease severity and treatment and experience of HIV-related discrimination were not statistically associated with the risk of work cessation. CONCLUSION: The risk of work cessation during the course of HIV disease has remained substantial in the most recent period in France. Comorbidities, but not characteristics of HIV disease itself, substantially affect chances of maintaining employment. This provides insights into strategies for limiting the burden of HIV disease for individuals and society.

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ba9cf73cc46477f65d9f4e8382eca09Test
https://doi.org/10.1097/qad.0b013e32834dcf61Test