التفاصيل البيبلوغرافية
| العنوان: |
High normal plasma triglycerides are associated with preserved cognitive function in Chinese oldest-old. |
| المؤلفون: |
Yin, Zhao-Xue, Shi, Xiao-Ming, Kraus, Virginia B., Fitzgerald, Simon M., Qian, Han-Zhu, Xu, Jian-Wei, Zhai, Yi, Sereny, Melanie D., Zeng, Yi |
| المصدر: |
Age & Ageing; Sep2012, Vol. 41 Issue 5, p600-606, 7p, 3 Charts |
| مصطلحات موضوعية: |
ANALYSIS of variance, CHI-squared test, COGNITION, COGNITION disorders, CONFIDENCE intervals, EPIDEMIOLOGY, LIPIDS, REGRESSION analysis, RESEARCH funding, TRIGLYCERIDES, LOGISTIC regression analysis, DATA analysis, CROSS-sectional method, DATA analysis software, OLD age |
| مصطلحات جغرافية: |
CHINA |
| مستخلص: |
Objective: to explore the relationship between blood lipids/lipoproteins and cognitive function in the Chinese oldest-old.Design: multivariate statistical analysis using cross-sectional data.Setting: community-based setting in longevity areas in China.Subjects: eight hundred and thirty-six subjects aged 80 and older were included in the sample.Methods: plasma total cholesterol, triglycerides, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, blood pressure and fasting plasma glucose were measured and information about demographics and lifestyle was collected. Cognitive status was assessed using the Mini-Mental State Examination (MMSE).Results: cumulative logit model analysis showed that triglyceride was significantly negatively associated with cognitive impairment. By general linear modelling, there was a significant linear trend of MMSE scores with the level of triglyceride, but not with levels of cholesterol after adjustment. The odds ratio (OR) of cognitive impairment (MMSE score < 18) was significantly reduced for the highest quartile of plasma triglyceride concentration (OR: 0.52, 95% CI: 0.33–0.84), but not for the second or third quartile, compared with the lowest quartile (adjusted models). There were no significant associations between cognitive impairment and cholesterol.Conclusion: we concluded that high normal plasma triglyceride was associated with preservation of cognitive function while lower concentrations were not in the Chinese oldest-old. [ABSTRACT FROM PUBLISHER] |
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| قاعدة البيانات: |
Complementary Index |
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