The aim of the present research is to simulate dynamic behavior of the human auditoria peripherals during sound transmission using the equivalent six-degrees-of-freedom lumped parameter mathematical model. Transmissibility analysis was employed to get a better insight into the sound transmission from tympanic membrane to malleus, incus, stapes, and cochlea. Furthermore, transmissibility from each member to corresponding adjacent member was carried out to functional analysis of the human ear. Simulation study illustrated that the results are in agreement with the experimental results published in the literature, and the proposed model provides more information in the dynamic analysis of middle ear biomechanics.