The benefit of using CT-perfusion imaging for reliable response monitoring in patients with gastrointestinal stromal tumor (GIST) undergoing treatment with novel targeted agents
| العنوان: | The benefit of using CT-perfusion imaging for reliable response monitoring in patients with gastrointestinal stromal tumor (GIST) undergoing treatment with novel targeted agents |
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| المؤلفون: | Martina Betz, Marius Horger, Claus D. Claussen, Hans-Georg Kopp, Daniel Spira |
| المصدر: | Acta Radiologica. 54:711-721 |
| بيانات النشر: | SAGE Publications, 2013. |
| سنة النشر: | 2013 |
| مصطلحات موضوعية: | medicine.medical_specialty, Stromal cell, Response to therapy, Gastrointestinal Stromal Tumors, Contrast Media, Antineoplastic Agents, Perfusion scanning, Imaging, Three-Dimensional, Humans, Medicine, Radiology, Nuclear Medicine and imaging, In patient, Stromal tumor, Protein Kinase Inhibitors, neoplasms, Gastrointestinal Neoplasms, Radiological and Ultrasound Technology, GiST, business.industry, General Medicine, Protein-Tyrosine Kinases, digestive system diseases, Radiographic Image Interpretation, Computer-Assisted, Radiology, Tomography, X-Ray Computed, business, Perfusion, Tyrosine kinase |
| الوصف: | Solely size-based response criteria may be unreliable in patients with gastrointestinal stromal tumors (GIST) treated with tyrosine kinase inhibitors, because they typically underestimate responses to treatment. As GISTs are generally hypervascularized and novel targeted drugs knowingly affect angiogenic signaling pathways, perfusion measurements are expected to deliver important information about their efficacy. This pictorial essay illustrates the benefit of using complementary CT-perfusion-based measurements for more accurate evaluation of response to therapy in GIST. |
| تدمد: | 1600-0455 0284-1851 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2d457f8b96966d8b585c062bf89b8c1Test https://doi.org/10.1177/0284185113484642Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....c2d457f8b96966d8b585c062bf89b8c1 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16000455 02841851 |
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