Imaging features of idiopathic intracranial hypertension, including a new finding: widening of the foramen ovale
| العنوان: | Imaging features of idiopathic intracranial hypertension, including a new finding: widening of the foramen ovale |
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| المؤلفون: | Ho K Lee, Luís F. Gonçalves, Ajay Agarwal, Selim R. Butros, Dustin Thompson |
| المصدر: | Acta Radiologica. 53:682-688 |
| بيانات النشر: | SAGE Publications, 2012. |
| سنة النشر: | 2012 |
| مصطلحات موضوعية: | Adult, Male, Optic nerve sheath, Sensitivity and Specificity, medicine, Humans, Radiology, Nuclear Medicine and imaging, In patient, Retrospective Studies, Intracranial pressure, Observer Variation, Pseudotumor Cerebri, Mass/lesion, Radiological and Ultrasound Technology, business.industry, Reproducibility of Results, General Medicine, Anatomy, Foramen ovale (skull), medicine.disease, Magnetic Resonance Imaging, Hydrocephalus, medicine.anatomical_structure, ROC Curve, Area Under Curve, Optic nerve, Female, Cerebrospinal fluid pressure, Tomography, X-Ray Computed, business, Foramen Ovale |
| الوصف: | Background Idiopathic intracranial hypertension (IIH) is a clinical disorder of unknown etiology manifesting with increased intracranial pressure in the absence of hydrocephalus, an underlying mass lesion, and demonstrating normal cerebrospinal fluid composition. IIH may exhibit several non-specific imaging findings including: an empty sella, posterior globe flattening, tortuosity of the optic nerve, and optic nerve sheath distention. Purpose To introduce widening of the foramen ovale as a new imaging marker for IIH. Material and Methods IIH is a syndrome which may exhibit several previously described non-specific imaging findings including: an empty sella, posterior globe flattening, tortuosity of the optic nerve, and optic nerve sheath distention. We hypothesize that chronically elevated cerebrospinal fluid pressure can lead to osseous erosions and we propose widening of the foramen ovale as a new imaging marker for IIH. Results Average foramen ovale sizes were increased in patients with IIH compared to controls (30.03 ± 7.00 mm2 vs. 24.21 ± 5.97 mm2, P < 0.001). For a cut-off value of 30 mm2, the sensitivity of FO area to detect IIH was 50%, with 81% specificity. Classic findings were significantly more common in patients with IIH compared to controls including: empty sella (65.9% vs. 0%), posterior globe flattening (65.9% vs. 4.5%), vertical tortuosity of the optic nerve (54.5% vs. 9.1%), and optic nerve sheath distention (52.3% vs. 11.4%, all P values < 0.001). Conclusion Our study confirms the association of several classic imaging findings with IIH and supports widening of the foramen ovale as an additional imaging marker which may be incorporated into the evaluation of patients suspected to have this condition. |
| تدمد: | 1600-0455 0284-1851 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f52c74de8724cb8f4908f8e6617ef48Test https://doi.org/10.1258/ar.2012.110705Test |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....3f52c74de8724cb8f4908f8e6617ef48 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16000455 02841851 |
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