HLA Antigens, Jejunal Morphology and Associated Diseases in Children with Dermatitis Herpetiformis
| العنوان: | HLA Antigens, Jejunal Morphology and Associated Diseases in Children with Dermatitis Herpetiformis |
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| المؤلفون: | P. Kuitunen, E Török, S. Karpati, M Verkasalo, Gyódi E, Zs. Simon, S. Koskimies, Timo Reunala, I Kosnai |
| المصدر: | Acta Paediatrica. 75:297-301 |
| بيانات النشر: | Wiley, 1986. |
| سنة النشر: | 1986 |
| مصطلحات موضوعية: | Hypersensitivity, Immediate, Male, Risk, Adolescent, Dermatitis Herpetiformis, Human leukocyte antigen, Coeliac disease, Atopy, 030207 dermatology & venereal diseases, 03 medical and health sciences, 0302 clinical medicine, Atrophy, Gene Frequency, HLA Antigens, Dermatitis herpetiformis, Biopsy, medicine, Humans, Villous atrophy, Family history, Child, Finland, Hungary, medicine.diagnostic_test, business.industry, Infant, General Medicine, medicine.disease, 3. Good health, Celiac Disease, Jejunum, Child, Preschool, 030220 oncology & carcinogenesis, Pediatrics, Perinatology and Child Health, Immunology, Female, business |
| الوصف: | Forty-five Hungarian and Finnish children from 1.5 to 15 years with dermatitis herpetiformis were studied for HLA antigens, jejunal morphology on gluten-containing diet and associated diseases in the patients and their relatives. A strong association with HLA-B8 was found in patients of both nationalities, the relative risks were 12.8 and 9.6, respectively. The Hungarian patients were also typed for HLA-DR locus, and an association with DR3 but not with DR7 was observed. Patients with subtotal villous atrophy had slightly more often HLA-B8 and DR3 than those with milder intestinal lesions. Atopic eczema occurred in 20% of the patients and family history of atopy seemed to have an inverse correlation with HLA-B8 and DR3. |
| تدمد: | 1651-2227 0803-5253 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::503a6c7eeef18bf0c10d9a505c7037adTest https://doi.org/10.1111/j.1651-2227.1986.tb10202.xTest |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....503a6c7eeef18bf0c10d9a505c7037ad |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 16512227 08035253 |
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