التفاصيل البيبلوغرافية
| العنوان: |
Increased risk of erectile dysfunction among males with central serous chorioretinopathy - a retrospective cohort study. |
| المؤلفون: |
Tsai, Der‐Chong, Huang, Chin‐Chou, Chen, Shih‐Jen, Chou, Pesus, Chung, Chia‐Min, Chan, Wan‐Leong, Huang, Po‐Hsun, Lin, Shing‐Jong, Chen, Jaw‐Wen, Leu, Hsin‐Bang |
| المصدر: |
Acta Ophthalmologica (1755375X); Nov2013, Vol. 91 Issue 7, p666-671, 6p |
| مصطلحات موضوعية: |
IMPOTENCE, NATIONAL health insurance, COHORT analysis, MIDDLE-aged men, KAPLAN-Meier estimator, CONFIDENCE intervals |
| مستخلص: |
. Purpose: Central serous chorioretinopathy (CSCR) mostly affects middle-aged men and has been associated with stress and hypercortisolism. We hypothesized that some factors prone to inducing CSCR could also have a harmful effect on erectile function. This study aimed to investigate the risk of subsequent erectile dysfunction after CSCR using Taiwan National Health Insurance Research Database. Methods: The study cohort ( n = 1220) consisted of newly diagnosed CSCR men aged 19-64 years between 1999 and 2007, and men matched for age, monthly income and time of enrolment were randomly selected as the control group ( n = 10870). Cox proportional hazard regressions were performed to calculate the hazard ratios (HR) of clinically diagnosed erectile dysfunction (including organic origin and/or psychogenic origin) for the two groups. Erectile dysfunction-free survival analysis was assessed using a Kaplan-Meier method. Results: Twenty-five patients (2.0%) from the CSCR cohort and 103 (0.9%) from the control group were diagnosed erectile dysfunction clinically during a mean observation period of 4.3 years. Patients with CSCR had a significantly higher incidence of erectile dysfunction diagnosis than those without CSCR (p < 0.001). After adjusting for age, geographic location, chronic comorbidities and medication habits, patients with CSCR were found to have a 2.22-fold [95% confidence interval (CI), 1.42-3.46] higher hazard ratio of a subsequent erectile dysfunction diagnosis than the matched controls. The adjusted HR for organic and psychogenic erectile dysfunction were 2.14 (95% CI: 1.34-3.44) and 3.83 (95% CI: 1.47-10.01), respectively. Conclusions: Central serous chorioretinopathy was independently associated with an increased risk of being diagnosed with erectile dysfunction. [ABSTRACT FROM AUTHOR] |
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| قاعدة البيانات: |
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