Exudative retinal detachment (ERD) may be seen with many ocular pathologies including malignancies. Among malignant causes, metastases of breast and lung carcinoma are most common. A 50-year-old woman referred to our clinic with history of decreased visual acuity in her right eye since 3 months before referral. The visual acuity was counting fingers at 2 meters and 6/10 in the right and left eyes, respectively. On slit lamp examination, 2+ anterior chamber and vitreous reaction was detected. On funduscopy, advanced ERD of the right eye and multiple subretinal masses with ERD in the left eye were detected. On systemic work up, bilateral multiple breast masses were found on mammography. Her breast biopsy showed advanced invasive intraductal adenocarcinoma. Any patient with ERD with undetermined cause should undergo a thorough systemic work up. Prompt intervention is imperative and may be life saving.
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