Major childhood infectious diseases and other determinants associated with type 1 diabetes: a case-control study
| العنوان: | Major childhood infectious diseases and other determinants associated with type 1 diabetes: a case-control study |
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| المؤلفون: | Mario Comelli, G. Devoti, M. Pinon, A. Capocchiano, Valeria Calcaterra, G Pretti, M. T. Tenconi |
| المساهمون: | Tenconi, Mt, Devoti, Gabriele, Comelli, M, Pinon, M, Capocchiano, A, Calcaterra, V, PRETTI G., AND THE PAVIA T1DM REGISTRY GROUP |
| المصدر: | Acta Diabetologica. 44:14-19 |
| بيانات النشر: | Springer Science and Business Media LLC, 2007. |
| سنة النشر: | 2007 |
| مصطلحات موضوعية: | Adult, Male, medicine.medical_specialty, Adolescent, Endocrinology, Diabetes and Metabolism, Population, Communicable Diseases, Endocrinology, Risk Factors, Internal medicine, Diabetes mellitus, Internal Medicine, medicine, Humans, Medical history, Age of Onset, Vitamin D, Child, education, Family Health, Type 1 diabetes, education.field_of_study, business.industry, Infant, Newborn, Case-control study, Infant, General Medicine, case control study, medicine.disease, scarlet fever, Breast Feeding, Diabetes Mellitus, Type 1, Case-Control Studies, Child, Preschool, Immunology, Scarlet fever, Female, childhood infection, Age of onset, business, Breast feeding, Type 1 diabetes mellitu |
| الوصف: | Aims - Evaluation of the association among infectious diseases and other events pertaining to childhood medical history and type 1 diabetes. Methods - A case-control study was carried out, taking as cases 159 type 1 diabetic patients (0-29 years) recorded from 1988 to 2000 within the population registry of the Pavia province (North Italy). As controls 318 non diabetic subjects were matched by age and sex. A questionnaire was administered by standardised interviewers. Data were analysed by conditional logistic regression. Results - Viral childhood diseases (OR 4.29; 95%CI 1.57-11.74) and bottle feeding (OR 1.83; 95%CI 1.08-3.09) were directly associated to type 1 diabetes; an inverse association was found for vitamin D administration during lactation (0-14 years) (OR 0.31; 95%CI 0.11-0.86) and for history of scarlet fever in both sexes and age groups (OR 0.19; 95%CI 0.08-0.46). Conclusions - Most associations of the studied variables confirm already known findings. The significant inverse association of type 1 diabetes with scarlet fever history is a peculiar finding, whose meaning is still obscure, although it has been recently described that streptococcal A infections are regulated by HLA class II alleles. |
| وصف الملف: | STAMPA |
| تدمد: | 1432-5233 0940-5429 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b0be20da22d6360b66da2a46e72eaeaTest https://doi.org/10.1007/s00592-007-0235-9Test |
| حقوق: | OPEN |
| رقم الانضمام: | edsair.doi.dedup.....8b0be20da22d6360b66da2a46e72eaea |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14325233 09405429 |
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