التفاصيل البيبلوغرافية
| العنوان: |
Highly Efficient Electrochemical Sensing of Acetaminophen by Cobalt Oxide-Embedded Nitrogen-Doped Hollow Carbon Spheres |
| المؤلفون: |
Duraisamy, Velu, Sudha, Velayutham, Dharuman, Venkataraman, Senthil Kumar, Sakkarapalayam Murugesan |
| المصدر: |
ACS Biomaterials Science & Engineering; March 2023, Vol. 9 Issue: 3 p1682-1693, 12p |
| مستخلص: |
With respect to sensor application investigations, hollow mesoporous carbon sphere-based materials of the spinel type of cobalt oxide (Co3O4) and heteroatom-doped materials are gaining popularity. In this contribution, dopamine hydrochloride (DA) and cobalt phthalocyanine (CoPc) precursors were employed to construct a highly homogeneous Co3O4-embedded N-doped hollow carbon sphere (Co3O4@NHCS) by a straightforward one-step polymerization procedure. The resulting Co3O4@NHCS materials may effectively tune the surface area, defect sites, and doping amount of N and Co elements by altering the loading amount of CoPc. The relatively high surface area, greater spherical wall thickness, enriched defect sites, and better extent of N and Co sites are all visible in the best 200 mg loaded Co3O4@NHCS-2 material. This leads to significant improvement in pyridine and graphitic N site concentrations, which offers exceptional electrochemical performance. Electrochemical analysis was used to study the electrocatalytic activity of Co3O4@NHCSs towards the sensing of pharmacologically active significant compounds (acetaminophen). Excellent sensor properties include the linear range (0.001–0.2 and 1.0–8.0 mM), sensitivity, limit of detection (0.07 and 0.11 μM), and selectivity in the modified Co3O4@NHCSs/GCE. The authentic sample (acetaminophen tablet) produces a satisfactory result when used practically. |
| قاعدة البيانات: |
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