Metabolic signatures of malignant and non-malignant mass-forming lesions in the periampulla and pancreas in FDG PET/CT scan: an atlas with pathologic correlation
| العنوان: | Metabolic signatures of malignant and non-malignant mass-forming lesions in the periampulla and pancreas in FDG PET/CT scan: an atlas with pathologic correlation |
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| المؤلفون: | Anish Bhattacharya, Sampath Santhosh, Bhagwant Rai Mittal, Ashim Das, Surinder Singh Rana, Radhika Srinivasan, Deepak K. Bhasin |
| المصدر: | Abdominal Imaging. 40:1285-1315 |
| بيانات النشر: | Springer Science and Business Media LLC, 2014. |
| سنة النشر: | 2014 |
| مصطلحات موضوعية: | Adult, Male, Ampulla of Vater, medicine.medical_specialty, Pathology, Adolescent, Urology, Common Bile Duct Neoplasms, Malignancy, Fluorodeoxyglucose F18, Internal medicine, medicine, Humans, Radiology, Nuclear Medicine and imaging, Aged, Autoimmune pancreatitis, Fluorodeoxyglucose, Radiological and Ultrasound Technology, medicine.diagnostic_test, business.industry, Gastroenterology, Pancreatic Diseases, General Medicine, Middle Aged, Hepatology, medicine.disease, Pancreatic Neoplasms, medicine.anatomical_structure, Positron emission tomography, Positron-Emission Tomography, Pancreatitis, Female, Radiology, Radiopharmaceuticals, Differential diagnosis, Tomography, X-Ray Computed, Pancreas, business, medicine.drug |
| الوصف: | Positron emission tomography (PET) has been used for the characterization of pancreatic and periampullary lesions. Pancreatitis-associated inflammation affecting only a portion of the pancreas gives the appearance of a mass lesion on imaging. Consequently, the differential diagnosis between cancer and pancreatitis becomes a commonly encountered problem. Traditionally, PET was interpreted as positive (to denote malignancy) if fluorodeoxyglucose (FDG) activity in the pancreas exceeded background activity and as negative (to denote benign) if activity was less than or equal to background activity. However, the specificity was limited with this method of interpretation. A relatively wide overlap has been reported between semiquantitative uptake values obtained in cancers and those in inflammatory lesions. Also, the qualitative (metabolic patterns) and quantitative variables (standardized uptake values) have been complementary and at sometimes controversial to each other in various clinical situations. There is paucity of data in the literature highlighting the role of FDG PET/CT in characterization of such mass lesions. The primary aim of this pictorial review is to list the various pathologic processes of pancreas and periampulla that could be studied with FDG PET/CT and recognize the different FDG uptake patterns and apply this information to characterize the different lesions affecting the pancreas and periampulla. We have also discussed the limitations of conventional imaging and advantages of FDG PET/CT for the evaluation mass-forming lesions of the pancreas and periampulla. |
| تدمد: | 1432-0509 0942-8925 |
| الوصول الحر: | https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1d0d2bc8c8fd4225f91cd1f2a760532Test https://doi.org/10.1007/s00261-014-0266-yTest |
| حقوق: | CLOSED |
| رقم الانضمام: | edsair.doi.dedup.....e1d0d2bc8c8fd4225f91cd1f2a760532 |
| قاعدة البيانات: | OpenAIRE |
| تدمد: | 14320509 09428925 |
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