دورية أكاديمية
Contribution of modifiable risk factors for hypertension and type-2 diabetes in Peruvian resource-limited settings
| العنوان: | Contribution of modifiable risk factors for hypertension and type-2 diabetes in Peruvian resource-limited settings |
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| المؤلفون: | Bernabe-Ortiz, A, Carrillo-Larco, RM, Gilman, RH, Checkley, W, Smeeth, L, Jaime Miranda, J |
| المصدر: | 55 ; 49 |
| بيانات النشر: | BMJ Publishing Group |
| سنة النشر: | 2015 |
| المجموعة: | Imperial College London: Spiral |
| مصطلحات موضوعية: | Science & Technology, Life Sciences & Biomedicine, Public, Environmental & Occupational Health, CARDIOVASCULAR-DISEASE, GLOBAL BURDEN, ATTRIBUTABLE RISK, PHYSICAL-ACTIVITY, ADULTS, POPULATION, PREVALENCE, ESTIMATORS, PREVENTION, COUNTRIES, DIABETES, Epidemiology of chronic non communicable diseases, HYPERTENSION, Adult, Aged, Cohort Studies, Cross-Sectional Studies, Diabetes Mellitus, Type 2, Female, Humans, Male, Middle Aged, Multivariate Analysis, Peru, Poverty Areas |
| الوصف: | Background It is important to understand the local burden of non-communicable diseases including within-country heterogeneity. The aim of this study was to characterise hypertension and type-2 diabetes profiles across different Peruvian geographical settings emphasising the assessment of modifiable risk factors. Methods Analysis of the CRONICAS Cohort Study baseline assessment was conducted. Cardiometabolic outcomes were blood pressure categories (hypertension, prehypertension, normal) and glucose metabolism disorder status (diabetes, prediabetes, normal). Exposures were study setting and six modifiable factors (smoking, alcohol drinking, leisure time and transport-related physical activity levels, TV watching, fruit/vegetables intake and obesity). Poisson regression models were used to report prevalence ratios (PR). Population attributable risks (PAR) were also estimated. Results Data from 3238 participants, 48.3% male, mean age 45.3 years, were analysed. Age-standardised (WHO population) prevalence of prehypertension and hypertension was 24% and 16%, whereas for prediabetes and type-2 diabetes it was 18% and 6%, respectively. Outcomes varied according to study setting (p<0.001). In multivariable model, hypertension was higher among daily smokers (PR 1.76), heavy alcohol drinkers (PR 1.61) and the obese (PR 2.06); whereas only obesity (PR 2.26) increased the prevalence of diabetes. PAR showed that obesity was an important determinant for hypertension (15.7%) and type-2 diabetes (23.9%). Conclusions There is an evident heterogeneity in the prevalence of and risk factors for hypertension and diabetes within Peru. Prehypertension and prediabetes are highly prevalent across settings. Our results emphasise the need of understanding the epidemiology of cardiometabolic conditions to appropriately implement interventions to tackle the burden of non-communicable diseases. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 0143-005X |
| العلاقة: | Journal of Epidemiology and Community Health; http://hdl.handle.net/10044/1/52860Test; https://dx.doi.org/10.1136/jech-2015-205988Test |
| DOI: | 10.1136/jech-2015-205988 |
| الإتاحة: | https://doi.org/10.1136/jech-2015-205988Test http://hdl.handle.net/10044/1/52860Test |
| حقوق: | © 2015 The Author(s). Published by the BMJ Publishing Group Limited. This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0Test/ |
| رقم الانضمام: | edsbas.2330F7B3 |
| قاعدة البيانات: | BASE |
| تدمد: | 0143005X |
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| DOI: | 10.1136/jech-2015-205988 |