Summary form only given. In our previous studies, we have found that during atmospheric pressure cold plasma treatment, oxidative stress pathways are required for yeast cell response. In addition, overexpressions of anti-oxidant SOD genes can remarkably protective yeast cells from plasma injury. These results are in coincidence with other groups' findings with mammalian cells, thus encouraging us to explore more on the anti-oxidative responses in eukaryotic cells subjected to plasma treatment.