مورد إلكتروني
Radiation survival of murine and human melanoma cells utilizing two assay systems: monolayer and soft agar.
| العنوان: | Radiation survival of murine and human melanoma cells utilizing two assay systems: monolayer and soft agar. |
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| المصدر: | British journal of cancer; vol 57, no 1, 64-69; 0007-0920 |
| بيانات النشر: | eScholarship, University of California 1988-01-01 |
| تفاصيل مُضافة: | Yohem, K H Slymen, D J Bregman, M D Meyskens, F L Jr |
| نوع الوثيقة: | Electronic Resource |
| مستخلص: | The radiation response of murine and human melanoma cells assayed in bilayer soft agar and monolayer was examined. Cells from the murine melanoma Cloudman S91 CCL 53.1 cell line and three human melanoma cell strains (C8146C, C8161, and R83-4) developed in our laboratory were irradiated by single dose X-rays and plated either in agar or on plastic. D0 values were the same within 95% confidence intervals for cells from the human melanoma cell strains C8146C, C8161, and R83-4 but were dissimilar for the murine cell line CCL 53.1 Dq values were different for all cells studied. The shape of the survival curve for all four melanomas was not identical for cells assayed in soft agar versus cells grown on plastic. This would indicate that apparent radiosensitivity was influenced by the method of assay although there were no apparent consistent differences between the curves generated by monolayer or bilayer soft agar assays. |
| مصطلحات الفهرس: | Medicine and Health Sciences, Animals, Cell Count, Cell Survival: radiation effects, Colony-Forming Units Assay, Dose-Response Relationship, Radiation, Humans, Mathematics, Melanoma: radiotherapy, Mice, Models, Biological, Tumor Cells, Cultured: radiation effects, Tumor Stem Cell Assay, animal cell, cell culture, comparative study, human, human cell, melanoma cell, methodology, nonhuman, radiosensitivity, Animal, Cell Survival, Human, Melanoma, Support, U.S. Gov't, P.H.S., Cultured, article |
| URL: | |
| الإتاحة: | Open access content. Open access content |
| ملاحظة: | 64 - 69 application/pdf British journal of cancer vol 57, no 1, 64-69 0007-0920 english |
| أرقام أخرى: | CDLER qt6272q7r7 qt6272q7r7 1025347634 |
| المصدر المساهم: | UC MASS DIGITIZATION From OAIster®, provided by the OCLC Cooperative. |
| رقم الانضمام: | edsoai.on1025347634 |
| قاعدة البيانات: | OAIster |
| الوصف غير متاح. |