المؤلفون: Bruce, E, Shenoy, V, Rathinasabapathy, A, Espejo, A, Horowitz, A, Oswalt, A, Francis, J, Nair, A, Unger, T, Raizada, M K, Steckelings, Ulrike Muscha, Sumners, C, Katovich, M J

المصدر: Bruce , E , Shenoy , V , Rathinasabapathy , A , Espejo , A , Horowitz , A , Oswalt , A , Francis , J , Nair , A , Unger , T , Raizada , M K , Steckelings , U M , Sumners , C & Katovich , M J 2015 , ' Selective activation of angiotensin AT 2 receptors attenuates progression of pulmonary hypertension and inhibits cardiopulmonary fibrosis ' , British Journal of Pharmacology , vol. 172 , no. 9 , pp. 2219-2231 . https://doi.org/10.1111/bph.13044Test

مصطلحات موضوعية: Angiotensin II Type 2 Receptor Blockers/pharmacology, Angiotensin II/analogs & derivatives, Animals, Cardiovascular Agents/pharmacology, Disease Models, Animal, Fibrosis, Hemodynamics/drug effects, Hypertension, Pulmonary/chemically induced, Hypertrophy, Right Ventricular/chemically induced, Imidazoles/pharmacology, Lung/drug effects, Male, Monocrotaline, Myocardium/metabolism, Peptide Fragments/pharmacology, Proto-Oncogene Proteins/antagonists & inhibitors, Pulmonary Fibrosis/chemically induced, Pyridines/pharmacology, Rats, Sprague-Dawley, Receptor, Angiotensin, Type 2/agonists, Receptors, G-Protein-Coupled/antagonists & inhibitors, Signal Transduction/drug effects, Vascular Remodeling/drug effects

العلاقة: https://portal.findresearcher.sdu.dk/da/publications/9a3e9de0-246f-4aaf-bda2-dd58392a466dTest

الإتاحة: https://doi.org/10.1111/bph.13044Test
https://portal.findresearcher.sdu.dk/da/publications/9a3e9de0-246f-4aaf-bda2-dd58392a466dTest

المؤلفون: Olmos, David, Barker, Douglas, Sharma, Rohini, Brunetto, Andre T, Yap, Timothy A, Taegtmeyer, Anne B, Barriuso, Jorge, Medani, Hanine, Degenhardt, Yan Y, Allred, Alicia J, Smith, Deborah A, Murray, Sharon C, Lampkin, Thomas A, Dar, Mohammed M, Wilson, Richard, de Bono, Johann S, Blagden, Sarah P

المصدر: Olmos , D , Barker , D , Sharma , R , Brunetto , A T , Yap , T A , Taegtmeyer , A B , Barriuso , J , Medani , H , Degenhardt , Y Y , Allred , A J , Smith , D A , Murray , S C , Lampkin , T A , Dar , M M , Wilson , R , de Bono , J S & Blagden , S P 2011 , ' Phase I study of GSK461364, a specific and competitive Polo-like kinase 1 inhibitor, in patients with advanced ....

مصطلحات موضوعية: Adenocarcinoma/drug therapy, Adult, Aged, 80 and over, Antineoplastic Agents/metabolism, Benzimidazoles/metabolism, Binding, Competitive, Cell Cycle Proteins/antagonists & inhibitors, Colorectal Neoplasms/drug therapy, Disease Progression, Female, Humans, Male, Maximum Tolerated Dose, Middle Aged, Neoplasms/drug therapy, Protein Kinase Inhibitors/metabolism, Protein-Serine-Threonine Kinases/antagonists & inhibitors, Proto-Oncogene Proteins/antagonists & inhibitors, Substrate Specificity, Thiophenes/metabolism, ResearchInstitutes_Networks_Beacons/mcrc, Manchester Cancer Research Centre

الإتاحة: https://doi.org/10.1158/1078-0432.CCR-10-2946Test
https://research.manchester.ac.uk/en/publications/f9070ec7-45a1-4859-ae6a-243f0e8a0d97Test