المؤلفون: Iannotta, Lucia, Emanuele, Marco, Favetta, Giulia, Tombesi, Giulia, Vandewynckel, Laurine, Lara Ordóñez, Antonio Jesús, Saliou, Jean-Michel, Drouyer, Matthieu, Sibran, William, Civiero, Laura, Nichols, R Jeremy, Athanasopoulos, Panagiotis S, Kortholt, Arjan, Chartier-Harlin, Marie-Christine, Greggio, Elisa, Taymans, Jean-Marc

المصدر: Iannotta , L , Emanuele , M , Favetta , G , Tombesi , G , Vandewynckel , L , Lara Ordóñez , A J , Saliou , J-M , Drouyer , M , Sibran , W , Civiero , L , Nichols , R J , Athanasopoulos , P S , Kortholt , A , Chartier-Harlin , M-C , Greggio , E & Taymans , J-M 2023 , ' PAK6-mediated phosphorylation of PPP2R2C regulates LRRK2-PP2A complex formation ' , Frontiers in Molecular Neuroscience , vol. 16 , 1269387 . https://doi.org/10.3389/fnmol.2023.1269387Test

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/ae2977dc-16a4-45b0-bb80-8ea839d518f6Test

الإتاحة: https://doi.org/10.3389/fnmol.2023.1269387Test
https://hdl.handle.net/11370/ae2977dc-16a4-45b0-bb80-8ea839d518f6Test
https://research.rug.nl/en/publications/ae2977dc-16a4-45b0-bb80-8ea839d518f6Test
https://pure.rug.nl/ws/files/874163457/fnmol-16-1269387.pdfTest

المؤلفون: Sabogal-Guáqueta, Angélica María, Marmolejo-Garza, Alejandro, Trombetta-Lima, Marina, Oun, Asmaa, Hunneman, Jasmijn, Chen, Tingting, Koistinaho, Jari, Lehtonen, Sarka, Kortholt, Arjan, Wolters, Justina C, Bakker, Barbara M, Eggen, Bart J L, Boddeke, Erik, Dolga, Amalia

المصدر: Sabogal-Guáqueta , A M , Marmolejo-Garza , A , Trombetta-Lima , M , Oun , A , Hunneman , J , Chen , T , Koistinaho , J , Lehtonen , S , Kortholt , A , Wolters , J C , Bakker , B M , Eggen , B J L , Boddeke , E & Dolga , A 2023 , ' Species-specific metabolic reprogramming in human and mouse microglia during inflammatory pathway induction ' , Nature Communications , vol. 14 , no. 1 , 6454 . https://doi.org/10.1038/s41467-023-42096-7Test

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/eee8923f-f2e0-4897-b1bc-4a1bdf27f830Test

الإتاحة: https://doi.org/10.1038/s41467-023-42096-7Test
https://hdl.handle.net/11370/eee8923f-f2e0-4897-b1bc-4a1bdf27f830Test
https://research.rug.nl/en/publications/eee8923f-f2e0-4897-b1bc-4a1bdf27f830Test
https://pure.rug.nl/ws/files/803513615/s41467-023-42096-7.pdfTest

المؤلفون: Pathak, Pragya, Alexander, Krista K, Helton, Leah G, Kentros, Michalis, LeClair, Timothy J, Zhang, Xiaojuan, Ho, Franz Y, Moore, Timothy T, Hall, Scotty, Guaitoli, Giambattista, Gloeckner, Christian Johannes, Kortholt, Arjan, Rideout, Hardy, Kennedy, Eileen J

المصدر: Pathak , P , Alexander , K K , Helton , L G , Kentros , M , LeClair , T J , Zhang , X , Ho , F Y , Moore , T T , Hall , S , Guaitoli , G , Gloeckner , C J , Kortholt , A , Rideout , H & Kennedy , E J 2023 , ' Doubly Constrained C-terminal of Roc (COR) Domain-Derived Peptides Inhibit Leucine-Rich Repeat Kinase 2 (LRRK2) Dimerization ' , ACS chemical neuroscience , vol. 14 , no. 11 , 00259 , pp. 1971-1980 . https://doi.org/10.1021/acschemneuro.3c00259Test

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/8b0f169c-49a7-4d9a-a76d-669929bf4f40Test

الإتاحة: https://doi.org/10.1021/acschemneuro.3c00259Test
https://hdl.handle.net/11370/8b0f169c-49a7-4d9a-a76d-669929bf4f40Test
https://research.rug.nl/en/publications/8b0f169c-49a7-4d9a-a76d-669929bf4f40Test
https://pure.rug.nl/ws/files/689526179/acschemneuro.3c00259.pdfTest

المؤلفون: Zhang, Xiaojuan, Kortholt, Arjan

المصدر: Zhang , X & Kortholt , A 2023 , ' LRRK2 Structure-Based Activation Mechanism and Pathogenesis ' , Biomolecules , vol. 13 , no. 4 , 612 . https://doi.org/10.3390/biom13040612Test

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/3dffab0f-5feb-44b8-b27e-e4ee1798ec38Test

الإتاحة: https://doi.org/10.3390/biom13040612Test
https://hdl.handle.net/11370/3dffab0f-5feb-44b8-b27e-e4ee1798ec38Test
https://research.rug.nl/en/publications/3dffab0f-5feb-44b8-b27e-e4ee1798ec38Test
https://pure.rug.nl/ws/files/625563821/biomolecules_13_00612_v2.pdfTest
https://www.mdpi.com/2218-273X/13/4/612Test

المؤلفون: Oun, Asmaa, Hoeksema, Emmy, Soliman, Ahmed, Brouwer, Famke, García-Reyes, Fabiola, Pots, Henderikus, Trombetta-Lima, Marina, Kortholt, Arjan, Dolga, Amalia M

المصدر: Oun , A , Hoeksema , E , Soliman , A , Brouwer , F , García-Reyes , F , Pots , H , Trombetta-Lima , M , Kortholt , A & Dolga , A M 2023 , ' Characterization of Lipopolysaccharide Effects on LRRK2 Signaling in RAW Macrophages ' , International Journal of Molecular Sciences , vol. 24 , no. 2 , 1644 . https://doi.org/10.3390/ijms24021644Test

مصطلحات موضوعية: Leucine-Rich Repeat Serine-Threonine Protein Kinase-2/genetics, Lipopolysaccharides/pharmacology, Reactive Oxygen Species, Signal Transduction, Macrophages/metabolism, Mutation

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/eb2afdd5-b9ca-44e7-b745-73aec74904ebTest

الإتاحة: https://doi.org/10.3390/ijms24021644Test
https://hdl.handle.net/11370/eb2afdd5-b9ca-44e7-b745-73aec74904ebTest
https://research.rug.nl/en/publications/eb2afdd5-b9ca-44e7-b745-73aec74904ebTest
https://pure.rug.nl/ws/files/565095629/ijms_24_01644_v2.pdfTest

المؤلفون: van Haastert, Peter J M, Keizer-Gunnink, Ineke, Kortholt, Arjan

المساهمون: Kimmel, Alan R.

المصدر: van Haastert , P J M , Keizer-Gunnink , I & Kortholt , A 2024 , Analysis of cGMP Signaling in Dictyostelium . in A R Kimmel (ed.) , Dictyostelium discoideum : Methods and Protocols . Methods in molecular biology (Clifton, N.J.) , vol. 2814 , Humana Press , pp. 177-194 . https://doi.org/10.1007/978-1-0716-3894-1_13Test

مصطلحات موضوعية: Dictyostelium/metabolism, Cyclic GMP/metabolism, Signal Transduction, Guanylate Cyclase/metabolism, Protozoan Proteins/metabolism

العلاقة: https://research.rug.nl/en/publications/f6577d9c-a027-4ce4-b96f-a6d613dc9abeTest

الإتاحة: https://doi.org/10.1007/978-1-0716-3894-1_13Test
https://hdl.handle.net/11370/f6577d9c-a027-4ce4-b96f-a6d613dc9abeTest
https://research.rug.nl/en/publications/f6577d9c-a027-4ce4-b96f-a6d613dc9abeTest

المؤلفون: van Haastert, Peter J M, Keizer-Gunnink, Ineke, Kortholt, Arjan

المساهمون: Kimmel, Alan R.

المصدر: van Haastert , P J M , Keizer-Gunnink , I & Kortholt , A 2024 , GRminusRD : A Sensitive Assay to Detect Activation Processes at the Plasma Membrane in Living Cells . in A R Kimmel (ed.) , Dictyostelium discoideum : Methods and protocols . Methods in molecular biology (Clifton, N.J.) , vol. 2814 , Humana Press , pp. 133-147 . https://doi.org/10.1007/978-1-0716-3894-1_10Test

مصطلحات موضوعية: Cell Membrane/metabolism, Green Fluorescent Proteins/metabolism, Humans, Luminescent Proteins/metabolism, Protein Transport, Microscopy, Fluorescence/methods, Cytosol/metabolism, Animals

العلاقة: https://research.rug.nl/en/publications/5d4e47ec-a689-4992-871e-8a23b0ad5fd7Test

الإتاحة: https://doi.org/10.1007/978-1-0716-3894-1_10Test
https://hdl.handle.net/11370/5d4e47ec-a689-4992-871e-8a23b0ad5fd7Test
https://research.rug.nl/en/publications/5d4e47ec-a689-4992-871e-8a23b0ad5fd7Test

المؤلفون: Xu, Xuehua, Pots, Henderikus, Gilsbach, Bernd K, Parsons, Dustin, Veltman, Douwe M, Ramachandra, Sharmila G, Li, Haoran, Kortholt, Arjan, Jin, Tian

المصدر: Xu , X , Pots , H , Gilsbach , B K , Parsons , D , Veltman , D M , Ramachandra , S G , Li , H , Kortholt , A & Jin , T 2022 , ' C2GAP2 is a common regulator of Ras signaling for chemotaxis, phagocytosis, and macropinocytosis ' , Frontiers in Immunology , vol. 13 , 1075386 . https://doi.org/10.3389/fimmu.2022.1075386Test

مصطلحات موضوعية: Dictyostelium/metabolism, Chemotaxis, Pinocytosis/physiology, Phagocytosis, Folic Acid, G protein coupled receptor, GTPase activating proteins (GAPs), macropinocytosis, model organism dictyostelium, ras

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/701b5b1f-ff2d-4470-afa2-280ce82121d2Test

الإتاحة: https://doi.org/10.3389/fimmu.2022.1075386Test
https://hdl.handle.net/11370/701b5b1f-ff2d-4470-afa2-280ce82121d2Test
https://research.rug.nl/en/publications/701b5b1f-ff2d-4470-afa2-280ce82121d2Test
https://pure.rug.nl/ws/files/347815504/fimmu_13_1075386.pdfTest

المؤلفون: Oun, Asmaa, Soliman, Ahmed, Trombetta-Lima, Marina, Tzepapadaki, Afroditi, Tsagkari, Dikaia, Kortholt, Arjan, Dolga, Amalia M

المصدر: Oun , A , Soliman , A , Trombetta-Lima , M , Tzepapadaki , A , Tsagkari , D , Kortholt , A & Dolga , A M 2022 , ' LRRK2 protects immune cells against erastin-induced ferroptosis ' , Neurobiology of Disease , vol. 175 , 105917 . https://doi.org/10.1016/j.nbd.2022.105917Test

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/4b76c361-58e0-4ece-abc5-912f757da280Test

الإتاحة: https://doi.org/10.1016/j.nbd.2022.105917Test
https://hdl.handle.net/11370/4b76c361-58e0-4ece-abc5-912f757da280Test
https://research.rug.nl/en/publications/4b76c361-58e0-4ece-abc5-912f757da280Test
https://pure.rug.nl/ws/files/261269884/1_s2.0_S0969996122003096_main_1_.pdfTest

المؤلفون: Arenales Arauz, Y Laurisa, Ahuja, Gargi, Kamsma, Ype P T, Kortholt, Arjan, van der Zee, Eddy A, van Heuvelen, Marieke J G

المصدر: Arenales Arauz , Y L , Ahuja , G , Kamsma , Y P T , Kortholt , A , van der Zee , E A & van Heuvelen , M J G 2022 , ' Potential of Whole-Body Vibration in Parkinson's disease : A systematic review and meta-analysis of human and animal studies ' , Biology , vol. 11 , no. 8 , 11081238 . https://doi.org/10.3390/biology11081238Test

وصف الملف: application/pdf

العلاقة: https://research.rug.nl/en/publications/f4478de9-ba9a-4097-9781-66cc6de2ec09Test

الإتاحة: https://doi.org/10.3390/biology11081238Test
https://hdl.handle.net/11370/f4478de9-ba9a-4097-9781-66cc6de2ec09Test
https://research.rug.nl/en/publications/f4478de9-ba9a-4097-9781-66cc6de2ec09Test
https://pure.rug.nl/ws/files/236925433/biology_11_01238_v3.pdfTest