المؤلفون: Jensen, Pernille Foged, Schoch, Angela, Larraillet, Vincent, Hilger, Maximiliane, Schlothauer, Tilman, Emrich, Thomas, Rand, Kasper Dyrberg

المصدر: Jensen , P F , Schoch , A , Larraillet , V , Hilger , M , Schlothauer , T , Emrich , T & Rand , K D 2017 , ' A Two-pronged Binding Mechanism of IgG to the Neonatal Fc Receptor Controls Complex Stability and IgG Serum Half-life ' , Molecular and Cellular Proteomics , vol. 16 , no. 3 , pp. 451-456 . https://doi.org/10.1074/mcp.M116.064675Test

مصطلحات موضوعية: Antibodies, Monoclonal/chemistry, Binding Sites, Deuterium Exchange Measurement/methods, Half-Life, Histocompatibility Antigens Class I/metabolism, Humans, Hydrogen-Ion Concentration, Immunoglobulin G/chemistry, Mass Spectrometry/methods, Models, Molecular, Protein Binding, Protein Stability, Receptors, Fc/metabolism

وصف الملف: application/pdf

الإتاحة: https://doi.org/10.1074/mcp.M116.064675Test
https://curis.ku.dk/portal/da/publications/a-twopronged-binding-mechanism-of-igg-to-the-neonatal-fc-receptor-controls-complex-stability-and-igg-serum-halflifeTest(17c9172d-f7ef-40e1-8929-838b76eb8e52).html
https://curis.ku.dk/ws/files/196136206/451.full.pdfTest

المؤلفون: Trabjerg, Esben, Kartberg, Fredrik, Christensen, Søren, Rand, Kasper D

المصدر: Trabjerg , E , Kartberg , F , Christensen , S & Rand , K D 2017 , ' Conformational characterization of nerve growth factor-β reveals that its regulatory pro-part domain stabilizes three loop regions in its mature part ' , Journal of Biological Chemistry , vol. 292 , no. 40 , pp. 16665-16676 . https://doi.org/10.1074/jbc.M117.803320Test

مصطلحات موضوعية: Crystallography, X-Ray, Deuterium Exchange Measurement, Glycosylation, Humans, Nerve Growth Factor, Protein Domains, Protein Precursors, Protein Stability, Protein Structure, Secondary, Journal Article

الإتاحة: https://doi.org/10.1074/jbc.M117.803320Test
https://curis.ku.dk/portal/da/publications/conformational-characterization-of-nerve-growth-factor-reveals-that-its-regulatory-propart-domain-stabilizes-three-loop-regions-in-its-mature-partTest(a4bbebcf-580f-4a9e-abca-53f94c452b5c).html

المؤلفون: Merkle, Patrick S, Irving, Melita, Hongjian, Song, Ferber, Mathias, Jørgensen, Thomas J D, Scholten, Kirsten, Luescher, Immanuel, Coukos, George, Zoete, Vincent, Cuendet, Michel A, Michielin, Olivier, Rand, Kasper D

المصدر: Merkle , P S , Irving , M , Hongjian , S , Ferber , M , Jørgensen , T J D , Scholten , K , Luescher , I , Coukos , G , Zoete , V , Cuendet , M A , Michielin , O & Rand , K D 2017 , ' The T-Cell Receptor Can Bind to the Peptide-Bound Major Histocompatibility Complex and Uncomplexed β 2 -Microglobulin through Distinct Binding Sites ' , Biochemistry , vol. 56 , no. 30 , pp. 3945-3961 . https://doi.org/10.1021/acs.biochem.7b00385Test

مصطلحات موضوعية: Amino Acid Substitution, Binding Sites, Cells, Cultured, Cytotoxicity, Immunologic, Deuterium Exchange Measurement, Humans, Kinetics, Ligands, Major Histocompatibility Complex, Models, Molecular, Molecular Docking Simulation, Molecular Dynamics Simulation, Mutation, Peptide Fragments, Protein Conformation, Protein Engineering, Protein Interaction Domains and Motifs, Protein Stability, Receptors, Antigen, T-Cell, alpha-beta, Recombinant Proteins, T-Lymphocytes, beta 2-Microglobulin, Journal Article

الإتاحة: https://doi.org/10.1021/acs.biochem.7b00385Test
https://curis.ku.dk/portal/da/publications/the-tcell-receptor-can-bind-to-the-peptidebound-major-histocompatibility-complex-and-uncomplexed-2microglobulin-through-distinct-binding-sitesTest(0728f582-54c7-4736-a07e-7cc53dc02b49).html

المؤلفون: Chung, Ka Young, Rasmussen, Søren Gøgsig Faarup, Liu, Tong, Li, Sheng, DeVree, Brian T, Chae, Pil Seok, Calinski, Diane, Kobilka, Brian K, Woods, Virgil L, Sunahara, Roger K

المصدر: Chung , K Y , Rasmussen , S G F , Liu , T , Li , S , DeVree , B T , Chae , P S , Calinski , D , Kobilka , B K , Woods , V L & Sunahara , R K 2011 , ' Conformational changes in the G protein Gs induced by the β2 adrenergic receptor ' , Nature , vol. 477 , no. 7366 , pp. 611-5 . https://doi.org/10.1038/nature10488Test

مصطلحات موضوعية: Adrenergic beta-2 Receptor Agonists, Animals, Biocatalysis, Catalytic Domain, Cattle, Crystallography, X-Ray, Deuterium Exchange Measurement, GTP-Binding Protein alpha Subunits, Gs, Guanosine Diphosphate, Guanosine Triphosphate, Humans, Models, Molecular, Protein Binding, Protein Conformation, Receptors, Adrenergic, beta-2

الإتاحة: https://doi.org/10.1038/nature10488Test
https://curis.ku.dk/portal/da/publications/conformational-changes-in-the-g-protein-gs-induced-by-the-2-adrenergic-receptorTest(63122bad-2071-4549-9f48-8ef6686bb22a).html

المؤلفون: Kjaergaard, Magnus, Gårdsvoll, Henrik, Hirschberg, Daniel, Nielbo, Steen, Mayasundari, Anand, Peterson, Cynthia B, Jansson, Anna, Jørgensen, Thomas J D, Poulsen, Flemming M, Ploug, Michael

المصدر: Kjaergaard , M , Gårdsvoll , H , Hirschberg , D , Nielbo , S , Mayasundari , A , Peterson , C B , Jansson , A , Jørgensen , T J D , Poulsen , F M & Ploug , M 2007 , ' Solution structure of recombinant somatomedin B domain from vitronectin produced in Pichia pastoris ' , Protein Science , vol. 16 , no. 9 , pp. 1934-1945 . https://doi.org/10.1110/ps.072949607Test

مصطلحات موضوعية: Amides, Crystallography, X-Ray, Deuterium Exchange Measurement, Disulfides, Humans, Mass Spectrometry, Nuclear Magnetic Resonance, Biomolecular, Pichia, Plasminogen Activator Inhibitor 1, Protein Structure, Tertiary, Solutions, Somatomedins, Vitronectin

العلاقة: https://portal.findresearcher.sdu.dk/da/publications/f3aa6080-e143-11dc-a57f-000ea68e967bTest

الإتاحة: https://doi.org/10.1110/ps.072949607Test
https://portal.findresearcher.sdu.dk/da/publications/f3aa6080-e143-11dc-a57f-000ea68e967bTest