دورية أكاديمية
Wheat glutenin proteins assemble into a nanostructure with unusual structural features
العنوان: | Wheat glutenin proteins assemble into a nanostructure with unusual structural features |
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المؤلفون: | Mackintosh, Sarah H., Meade, Susie J., Healy, Jackie P., Sutton, Kevin H., Larsen, Nigel G., Squires, Adam M., Gerrard, Juliet A. |
المصدر: | Mackintosh , S H , Meade , S J , Healy , J P , Sutton , K H , Larsen , N G , Squires , A M & Gerrard , J A 2009 , ' Wheat glutenin proteins assemble into a nanostructure with unusual structural features ' , Journal of Cereal Science , vol. 49 , no. 1 , pp. 157-162 . https://doi.org/10.1016/j.jcs.2008.08.003Test |
سنة النشر: | 2009 |
الوصف: | The proteins of wheat have a known propensity to aggregate into a variety of forms. We report here a novel nanostructure from wheat proteins, derived from a crude extract of high molecular weight glutenins. The structure was characterised by a significant thioflavin T (ThT) fluorescence and a fibrillar morphology by transmission electron microscopy (TEM). The ThT fluorescence and TEM data are suggestive of an amyloid structure, but the X-ray fibre diffraction data show a reflection pattern (4.02, 4.2–4.3, 4.6, 12.9, 19.3 and 38.7 Å) inconsistent with both the classic amyloid form and the previously described β-helix structure. The 4.6 Å reflection is consistent with that predicted for the amyloid inter-β-strand, and the absence of the inter-β-sheet distance at ≈10–11 Å is not unprecedented in amyloid-like structures. However, our observed X-ray reflection pattern has not been previously reported and suggests a novel wheat glutenin nanostructure. |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
العلاقة: | https://researchportal.bath.ac.uk/en/publications/886f1794-79bc-4b45-8001-9fb8100d8fc2Test |
DOI: | 10.1016/j.jcs.2008.08.003 |
الإتاحة: | https://doi.org/10.1016/j.jcs.2008.08.003Test https://researchportal.bath.ac.uk/en/publications/886f1794-79bc-4b45-8001-9fb8100d8fc2Test |
حقوق: | info:eu-repo/semantics/restrictedAccess |
رقم الانضمام: | edsbas.9192139C |
قاعدة البيانات: | BASE |
DOI: | 10.1016/j.jcs.2008.08.003 |
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