دورية أكاديمية

Wheat glutenin proteins assemble into a nanostructure with unusual structural features

التفاصيل البيبلوغرافية
العنوان: Wheat glutenin proteins assemble into a nanostructure with unusual structural features
المؤلفون: Mackintosh, Sarah H., Meade, Susie J., Healy, Jackie P., Sutton, Kevin H., Larsen, Nigel G., Squires, Adam M., Gerrard, Juliet A.
المصدر: Mackintosh , S H , Meade , S J , Healy , J P , Sutton , K H , Larsen , N G , Squires , A M & Gerrard , J A 2009 , ' Wheat glutenin proteins assemble into a nanostructure with unusual structural features ' , Journal of Cereal Science , vol. 49 , no. 1 , pp. 157-162 . https://doi.org/10.1016/j.jcs.2008.08.003Test
سنة النشر: 2009
الوصف: The proteins of wheat have a known propensity to aggregate into a variety of forms. We report here a novel nanostructure from wheat proteins, derived from a crude extract of high molecular weight glutenins. The structure was characterised by a significant thioflavin T (ThT) fluorescence and a fibrillar morphology by transmission electron microscopy (TEM). The ThT fluorescence and TEM data are suggestive of an amyloid structure, but the X-ray fibre diffraction data show a reflection pattern (4.02, 4.2–4.3, 4.6, 12.9, 19.3 and 38.7 Å) inconsistent with both the classic amyloid form and the previously described β-helix structure. The 4.6 Å reflection is consistent with that predicted for the amyloid inter-β-strand, and the absence of the inter-β-sheet distance at ≈10–11 Å is not unprecedented in amyloid-like structures. However, our observed X-ray reflection pattern has not been previously reported and suggests a novel wheat glutenin nanostructure.
نوع الوثيقة: article in journal/newspaper
اللغة: English
العلاقة: https://researchportal.bath.ac.uk/en/publications/886f1794-79bc-4b45-8001-9fb8100d8fc2Test
DOI: 10.1016/j.jcs.2008.08.003
الإتاحة: https://doi.org/10.1016/j.jcs.2008.08.003Test
https://researchportal.bath.ac.uk/en/publications/886f1794-79bc-4b45-8001-9fb8100d8fc2Test
حقوق: info:eu-repo/semantics/restrictedAccess
رقم الانضمام: edsbas.9192139C
قاعدة البيانات: BASE