Use of ciclesonide for the treatment of inflammatory bowel diseases

التفاصيل البيبلوغرافية
العنوان: Use of ciclesonide for the treatment of inflammatory bowel diseases
Document Number: 20060211668
تاريخ النشر: September 21, 2006
Appl. No: 10/570986
Application Filed: September 15, 2004
مستخلص: The invention relates to the novel use of ciclesonide in the treatment of inflammatory bowel disease.
Inventors: Abel, Florian (Bondmann-Ludwigshafen, DE); Brueck, Antje (Konstanz, DE); Dietzel, Klaus (Konstanz, DE); Eistetter, Klaus (Konstanz, DE); Nave, Ruediger (Konstanz, DE); Postius, Stefan (Konstanz, DE); Von Richter, Oliver (Kontanz, DE)
Assignees: ALTANA PHARMA AG (Konstanz, DE)
Claim: 1.-6. (canceled)
Claim: 7. A pharmaceutical composition comprising a therapeutically effective amount of ciclesonide and a pharmaceutically acceptable carrier and/or excipient suitable for oral administration allowing targeted release of ciclesonide in the small intestine and/or colon.
Claim: 8. The pharmaceutical composition according to claim 7, comprising a core formulation containing ciclesonide and a coating providing a release profile allowing targeted release of ciclesonide in the small intestine and/or colon.
Claim: 9. The pharmaceutical composition according to claim 8, wherein the core formulation is a granulate, a pellet or a tablet.
Claim: 10. The pharmaceutical composition according to claim 9, wherein the core formulation is an immediate release formulation.
Claim: 11. The pharmaceutical composition according to claim 8, comprising at least one enteric coating and/or at least one slow release coating.
Claim: 12. The pharmaceutical composition according to claim 11, comprising a combination of one enteric coating and one slow release coating.
Claim: 13. A method of treatment of inflammatory bowel disease in a patient comprising administering a therapeutically effective amount of ciclesonide to the patient in need thereof.
Claim: 14. The method according to claim 13, wherein the inflammatory bowel disease is selected from the group consisting of Crohn's disease and ulcerative colitis.
Claim: 15. A method of treatment of inflammatory bowel disease in a patient comprising administering a therapeutically effective amount of ciclesonide to the patient in need thereof, wherein the ciclesonide is administered in a pharmaceutical composition according to claim 7.
Claim: 16. The method according to claim 13, wherein ciclesonide is administered rectally.
Claim: 17. The pharmaceutical composition according to claim 7, wherein more than 95% of the ciclesonide present is in the form of its R epimer.
Claim: 18. A method of treatment of inflammatory bowel disease in a patient comprising administering a therapeutically effective amount of ciclesonide to the patient in need thereof, wherein the ciclesonide is administered in a pharmaceutical composition according to claim 8.
Claim: 19. A method of treatment of inflammatory bowel disease in a patient comprising administering a therapeutically effective amount of ciclesonide to the patient in need thereof, wherein the ciclesonide is administered in a pharmaceutical composition according to claim 9.
Claim: 20. A method of treatment of inflammatory bowel disease in a patient comprising administering a therapeutically effective amount of ciclesonide to the patient in need thereof, wherein the ciclesonide is administered in a pharmaceutical composition according to claim 10.
Claim: 21. A method of treatment of inflammatory bowel disease in a patient comprising administering a therapeutically effective amount of ciclesonide to the patient in need thereof, wherein the ciclesonide is administered in a pharmaceutical composition according to claim 11.
Claim: 22. A method of treatment of inflammatory bowel disease in a patient comprising administering a therapeutically effective amount of ciclesonide to the patient in need thereof, wherein the ciclesonide is administered in a pharmaceutical composition according to claim 12.
Claim: 23. A method of treatment of inflammatory bowel disease in a patient comprising administering a therapeutically effective amount of ciclesonide to the patient in need thereof, wherein the ciclesonide is administered in a pharmaceutical composition according to claim 17.
Current U.S. Class: 514179/000
Current International Class: 61
رقم الانضمام: edspap.20060211668
قاعدة البيانات: USPTO Patent Applications