نتائج البحث - "physiologically based pharmacokinetics"

1

Prediction of Moxifloxacin Concentrations in Tuberculosis Patient Populations by Physiologically Based Pharmacokinetic Modeling

المصدر: Journal of clinical pharmacology. 62(3):385-396

مصطلحات موضوعية: drug-drug interactions, modeling, moxifloxacin, physiologically based pharmacokinetics, tuberculosis

وصف الملف: electronic

الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-479427Test
https://doi.org/10.1002/jcph.1972Test
https://uu.diva-portal.org/smash/get/diva2:1678957/FULLTEXT01.pdfTest

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2

Mechanistic Based Pharmacokinetic-Pharmacodynamics models for Drug Interactions and Disease Population Predictions

المؤلفون: Garcia, Luna Prieto, 1988

المساهمون: Sjögren, Erik, 1977, Galetin, Aleksandra, Professor

المصدر: Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Pharmacy.

مصطلحات موضوعية: Physiologically-Based Pharmacokinetics, Pharmacokinetics, Pharmacodynamics, Disease Modelling, Drug Interactions, Statins, Mechanistic Modelling, Farmakokinetik och läkemedelsterapi, Pharmacokinetics and Drug Therapy

وصف الملف: electronic

الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-515485Test
https://uu.diva-portal.org/smash/get/diva2:1809415/FULLTEXT01.pdfTest
https://uu.diva-portal.org/smash/get/diva2:1809415/PREVIEW01.jpgTest

View record in SwePub

3

General clinical and methodological considerations on the extrapolation of pharmacokinetics and optimization of study protocols for small molecules and monoclonal antibodies in children

المؤلفون: Bouazza, Naim, Dokoumetzidis, Aristides, Knibbe, Catherijne A. J., de Wildt, Saskia N., Ambery, Claire, De Cock, Pieter A., Gasthuys, Elke, Foissac, Frantz, Urien, Saik, Hamberg, Anna-Karin, 1964, Poggesi, Italo, Zhao, Wei, Vermeulen, An, Standing, Joseph F., Treluyer, Jean-Marc

المصدر: British Journal of Clinical Pharmacology. 88(12):4985-4996

مصطلحات موضوعية: allometry, modelling, paediatric, physiologically based pharmacokinetics, pharmacometrics, simulation

وصف الملف: print

الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-497520Test

4

IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 2: An introduction to the simulation exercise and overview of results

المؤلفون: Margolskee, Alison, Darwich, Adam S., Pepin, Xavier, Aarons, Leon, Galetin, Aleksandra, Rostami-Hodjegan, Amin, Carlert, Sara, Hammarberg, Maria, Hilgendorf, Constanze, Johansson, Pernilla, Karlsson, Eva, Murphy, Donal, Tannergren, Christer, Thorn, Helena, Yasin, Mohammed, Mazuir, Florent, Nicolas, Olivier, Ramusovic, Sergej, Xu, Christine, Pathak, Shriram M., Korjamo, Timo, Laru, Johanna, Malkki, Jussi, Pappinen, Sari, Tuunainen, Johanna, Dressman, Jennifer, Hansmanni, Simone, Kostewicz, Edmund, He, Handan, Heimbach, Tycho, Wu, Fan, Hoft, Carolin, Laplanche, Loic, Pang, Yan, Bolger, Michael B., Huehn, Eva, Lukacova, Viera, Mullin, James M., Szeto, Ke X., Costales, Chester, Lin, Jian, McAllister, Mark, Modi, Sweta, Rotter, Charles, Varma, Manthena, Wong, Mei, Mitra, Amitava, Bevernage, Jan, Biewenga, Jeike, Van Peer, Achiel, Lloyd, Richard, Shardlow, Carole, Langguth, Peter, Mishenzon, Irina, Nguyen, Mai Anh, Brown, Jonathan, Lennernäs, Hans, Abrahamsson, Bertil

المصدر: European Journal of Pharmaceutical Sciences. 96:610-625

مصطلحات موضوعية: Physiologically-based pharmacokinetics (PBPK), Modelling and simulation (M&S), Absorption, Oral bioavailability (F-oral), Biopharmaceutics, Drug database

وصف الملف: print

الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-361077Test

5

IMI - Oral biopharmaceutics tools project - Evaluation of bottom-up PBPK prediction success part 3: Identifying gaps in system parameters by analysing In Silico performance across different compound classes

المؤلفون: Darwich, Adam S., Margolskee, Alison, Pepin, Xavier, Aarons, Leon, Galetin, Aleksandra, Rostami-Hodjegan, Amin, Carlert, Sara, Hammarberg, Maria, Hilgendorf, Constanze, Johansson, Pernilla, Karlsson, Eva, Murphy, Donal, Tannergren, Christer, Thorn, Helena, Yasin, Mohammed, Mazuir, Florent, Nicolas, Olivier, Ramusovic, Sergej, Xu, Christine, Pathak, Shriram M., Korjamo, Timo, Laru, Johanna, Malkki, Jussi, Pappinen, Sari, Tuunainen, Johanna, Dressman, Jennifer, Hansmann, Simone, Kostewicz, Edmund, He, Handan, Heimbach, Tycho, Wu, Fan, Hoft, Carolin, Pang, Yan, Bolger, Michael B., Huehn, Eva, Lukacova, Viera, Mullin, James M., Szeto, Ke X., Costales, Chester, Lin, Jian, McAllister, Mark, Modi, Sweta, Rotter, Charles, Varma, Manthena, Wong, Mei, Mitra, Amitava, Bevernage, Jan, Biewenga, Jeike, Van Peer, Achiel, Lloyd, Richard, Shardlow, Carole, Langguth, Peter, Mishenzon, Irina, Nguyen, Mai Anh, Brown, Jonathan, Lennernäs, Hans, Abrahamsson, Bertil

المصدر: European Journal of Pharmaceutical Sciences. 96:626-642

مصطلحات موضوعية: Physiologically-based pharmacokinetics (PBPK), modelling and simulation (M&S), absorption, oral bioavailability (F-oral), biopharmaceutics, drug database

وصف الملف: print

الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-361078Test

6

IMI - oral biopharmaceutics tools project - evaluation of bottom-up PBPK prediction success part 1: Characterisation of the OrBiTo database of compounds

المؤلفون: Margolskee, Alison, Darwich, Adam S., Pepin, Xavier, Pathak, Shriram M., Bolger, Michael B., Aarons, Leon, Rostami-Hodjegan, Amin, Angstenberger, Jonas, Graf, Franziska, Laplanche, Loic, Mueller, Thomas, Carlert, Sara, Daga, Pankaj, Murphy, Donal, Tannergren, Christer, Yasin, Mohammed, Greschat-Schade, Susanne, Mueck, Wolfgang, Muenster, Uwe, van der Mey, Dorina, Frank, Kerstin Julia, Lloyd, Richard, Adriaenssen, Lieve, Bevernage, Jan, De Zwart, Loeckie, Swerts, Dominique, Tistaert, Christophe, Van Den Bergh, An, Van Peer, Achiel, Beato, Stefania, Nguyen-Trung, Anh-Thu, Bennett, Joanne, McAllister, Mark, Wong, Mei, Zane, Patricia, Ollier, Celine, Vicat, Pascale, Kolhmann, Markus, Marker, Alexander, Brun, Priscilla, Mazuir, Florent, Beilles, Stephane, Venczel, Marta, Boulenc, Xavier, Loos, Petra, Lennernäs, Hans, Abrahamsson, Bertil

المصدر: European Journal of Pharmaceutical Sciences. 96:598-609

مصطلحات موضوعية: Physiologically-based pharmacokinetics (PBPK), Modelling and simulation (M&S), Absorption, Oral bioavailability (F-oral), Biopharmaceutics, Drug database

وصف الملف: print

الوصول الحر: https://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-361061Test

7

Physiologically-Based Toxicokinetic Model for Cadmium Using Markov-Chain Monte Carlo Analysis of Concentrations in Blood, Urine, and Kidney Cortex from Living Kidney Donors

المؤلفون: Fransson, M. N., Barregård, Lars, 1948, Sällsten, Gerd, 1952, Åkerström, Magnus, 1981, Johanson, G.

المصدر: Toxicological Sciences. 141(2):365-376

مصطلحات موضوعية: Clinical Medicine, Klinisk medicin, cadmium, physiologically-based pharmacokinetics, exposure assessment, PROSPECTIVE COHORT, DIETARY-CADMIUM, EXPOSURE, POPULATION, DISPOSITION, TOXICITY, SWEDEN, HEALTH, MASS, Toxicology

الوصول الحر: https://gup.ub.gu.se/publication/205637Test

8

Prediction of drug tissue to plasma concentration ratios using a measured volume of distribution in combination with lipophilicity

المؤلفون: Jansson, Rasmus, 1979, Bredberg, Ulf, Ashton, Michael, 1955

المصدر: Journal of Pharmaceutical Sciences. 97(6):2324-2339

مصطلحات موضوعية: Chemical Sciences, Kemi, Other Clinical Medicine, Annan klinisk medicin, Pharmaceutical Sciences, Farmaceutisk vetenskap, physiologically based pharmacokinetics, beta-lactam antibiotics, partition-coefficients, in-vivo, basic drugs, protein binding, blood-flow, pethidine binding, steady-state, pregnant rat

الوصول الحر: https://gup.ub.gu.se/publication/96500Test

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