التفاصيل البيبلوغرافية
| العنوان: |
Experimental Stent-Graft Treatment of Ascending Aortic Dissection. |
| المؤلفون: |
Zimpfer, Daniel, Schima, Heinz, Czerny, Martin, Kasimir, Marie-Theres, Sandner, Sigrid, Seebacher, Gernot, Losert, Udo, Simon, Paul, Grimm, Michael, Wolner, Ernst, Ehrlich, Marek |
| المصدر: |
Annals of Thoracic Surgery; Feb2008, Vol. 85 Issue 2, p470-473, 4p |
| مصطلحات موضوعية: |
AORTIC dissection, MEDICAL imaging systems, RECIPROCATING pumps, AORTIC aneurysms |
| مستخلص: |
Background: This study assessed the feasibility of stent graft treatment of ascending aortic dissections in a porcine in vitro model. Methods: The entire thoracic aortic aorta including the supraaortic branches was harvested from 12 adult pigs and an intimal tear was artificially created. The aortic annulus was then sewn into a silicon ring of a driving chamber. The distal aorta was connected to tubing with adjustable resistance elements. The circulation was driven by a hydraulic motor piston pump to mimic aortic flow and pressure. After creating a dissection by elevating the systolic aortic pressure to 180 mm Hg, a 2- × 2.6-cm covered stent graft was inserted through the brachiocephalic trunk using a specially designed delivery system. Stent graft placement was performed under continuous ultrasound control. Results: The longitudinal length of the created ascending aortic dissection was 1.8 ± 0.39 cm. Ultrasound studies revealed successful deployment of the stent graft and closure of the false lumen in all 12 cases. Diameter and area of the true lumen increased from 0.52 ± 0.15 cm to 2.54 ± 0.36 cm (p < 0.05) and from 0.78 ± 0.27 cm2 to 5.13 ± 1.35 cm2 (p < 0.05), respectively. The circumference of the true lumen increased from 4.50 ± 0.52 cm to 7.96 ± 1.2 cm (p < 0.05). Ultrasound studies also revealed uncompromised function of the aortic valve in all cases. No dislodging of stent grafts was observed. Conclusions: Given ideal anatomy, experimental stent graft placement for ascending aortic dissection is feasible and achieves complete closure of the false lumen. [Copyright &y& Elsevier] |
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