التفاصيل البيبلوغرافية
| العنوان: |
Lemon myrtle extract inhibits lactate production by Streptococcus mutans. |
| المؤلفون: |
Yabuta, Yukinori, Sato, Yui, Miki, Arisu, Nagata, Ryuta, Bito, Tomohiro, Ishihara, Atsushi, Watanabe, Fumio |
| المصدر: |
Bioscience, Biotechnology & Biochemistry; Oct2021, Vol. 85 Issue 10, p2185-2190, 6p |
| مصطلحات موضوعية: |
STREPTOCOCCUS mutans, LEMON, LACTATES, ELLAGIC acid, DENTAL enamel, QUERCETIN, LACTATION, LACTATE dehydrogenase |
| مستخلص: |
Backhousia citriodora (lemon myrtle) extract has been found to inhibit glucansucrase activity, which plays an important role in biofilm formation by Streptococcus mutans. In addition to glucansucrase, various virulence factors in S. mutans are involved in the initiation of caries. Lactate produced by S. mutans demineralizes the tooth enamel. This study investigated whether lemon myrtle extract can inhibit S. mutans lactate production. Lemon myrtle extract reduced the glycolytic pH drop in S. mutans culture and inhibited lactate production by at least 46%. Ellagic acid, quercetin, hesperetin, and myricetin, major polyphenols in lemon myrtle, reduced the glycolytic pH drop and lactate production, but not lactate dehydrogenase activity. Furthermore, these polyphenols reduced the viable S. mutans cell count. Thus, lemon myrtle extracts may inhibit S. mutans -mediated acidification of the oral cavity, thereby preventing dental caries and tooth decay. [ABSTRACT FROM AUTHOR] |
|
Copyright of Bioscience, Biotechnology & Biochemistry is the property of Oxford University Press / USA and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) |
| قاعدة البيانات: |
Supplemental Index |
