التفاصيل البيبلوغرافية
| العنوان: |
Alteration of Coenzyme Specificity of Lactate Dehydrogenase from Thermus thermophilus by Introducing the Loop Region of NADP(H)-Dependent Malate Dehydrogenase. |
| المؤلفون: |
Tomita, Takeo, Kuzuyama, Tomohisa, Nishiyama, Makoto |
| المصدر: |
Bioscience, Biotechnology & Biochemistry; Sep2006, Vol. 70 Issue 9, p2230-2235, 6p, 1 Chart |
| مصطلحات موضوعية: |
LACTATE dehydrogenase, COENZYMES, DEHYDROGENASES, BIOCHEMISTRY, BIOTECHNOLOGY |
| مصطلحات جغرافية: |
JAPAN |
| مستخلص: |
The article focuses on the study conducted in Japan regarding the introduction of the loop region of NADPH-dependent malate dehydrogenase through the replacement of coenzyme specifity of lactate deghydrogenase from Thermus thermophilus. The authors discuss the effects of the replacement on coenzyme specifity based on the structure of the lactate dehydrogenase mutant. Moreover, they talk about the value and enhanced catalytic efficiency of NADPH. |
| قاعدة البيانات: |
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