دورية أكاديمية

Expression of p53 and lactate dehydrogenase in murine fibrosarcoma following exposure to gamma-radiation

التفاصيل البيبلوغرافية
العنوان: Expression of p53 and lactate dehydrogenase in murine fibrosarcoma following exposure to gamma-radiation
المؤلفون: Huilgol, Nagaraj G., Nair, CherupallyKrishnan K., Rajagopalan, Rema, Wani, Khalida
المصدر: Journal of Environmental Pathology, Toxicology & Oncology; 2001, Vol. 20 Issue 1, p33, 0p
مصطلحات موضوعية: BIOCHEMISTRY, LACTATE dehydrogenase, PATHOLOGY, RADIATION exposure
مستخلص: Radiation-induced alterations in the levels of p53 and lactate dehydrogenase activities were studied in fibrosarcoma, following exposure to different doses of Gamma-irradiation (2-10 Gy). The levels of p53 were elevated in the cytoplasm, while the lactate dehydrogenase activity in tumor tissue was considerably decreased. [ABSTRACT FROM AUTHOR]
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