دورية
Prognosis of ALK-rearranged non-small-cell lung cancer patients carrying TP53mutations
العنوان: | Prognosis of ALK-rearranged non-small-cell lung cancer patients carrying TP53mutations |
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المؤلفون: | Canale, Matteo, Petracci, Elisabetta, Cravero, Paola, Mariotti, Marita, Minuti, Gabriele, Metro, Giulio, Ludovini, Vienna, Baglivo, Sara, Puccetti, Maurizio, Dubini, Alessandra, Martinelli, Giovanni, Delmonte, Angelo, Crinò, Lucio, Ulivi, Paola |
المصدر: | Translational Oncology; September 2022, Vol. 23 Issue: 1 |
مستخلص: | •Non-small-cell lung cancer is the primary cause of cancer-related death. TP53mutations affect patients prognosis, also in oncogene-addicted subgroup. We investigated the role of TP53mutations in predicting response to therapy and prognosis in ALK-rearranged NSCLC patients, finding that specific TP53mutations are able to influence patients prognosis. |
قاعدة البيانات: | Supplemental Index |
تدمد: | 19447124 19365233 |
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DOI: | 10.1016/j.tranon.2022.101471 |