Prognosis of ALK-rearranged non-small-cell lung cancer patients carrying TP53mutations

التفاصيل البيبلوغرافية
العنوان: Prognosis of ALK-rearranged non-small-cell lung cancer patients carrying TP53mutations
المؤلفون: Canale, Matteo, Petracci, Elisabetta, Cravero, Paola, Mariotti, Marita, Minuti, Gabriele, Metro, Giulio, Ludovini, Vienna, Baglivo, Sara, Puccetti, Maurizio, Dubini, Alessandra, Martinelli, Giovanni, Delmonte, Angelo, Crinò, Lucio, Ulivi, Paola
المصدر: Translational Oncology; September 2022, Vol. 23 Issue: 1
مستخلص: •Non-small-cell lung cancer is the primary cause of cancer-related death. TP53mutations affect patients prognosis, also in oncogene-addicted subgroup. We investigated the role of TP53mutations in predicting response to therapy and prognosis in ALK-rearranged NSCLC patients, finding that specific TP53mutations are able to influence patients prognosis.
قاعدة البيانات: Supplemental Index
الوصف
تدمد:19447124
19365233
DOI:10.1016/j.tranon.2022.101471