دورية أكاديمية

Antibody selection strategies and their impact in predicting clinical malaria based on multi-sera data

التفاصيل البيبلوغرافية
العنوان: Antibody selection strategies and their impact in predicting clinical malaria based on multi-sera data
المؤلفون: Fonseca, André, Spytek, Mikolaj, Biecek, Przemysław, Cordeiro, Clara, Sepúlveda, Nuno
المساهمون: Sapientia
بيانات النشر: BMC, 2024.
سنة النشر: 2024
مصطلحات موضوعية: Multivariate serological data, Super learner, Statistical modelling, Malaria outcome prediction, Random forest
الوصف: Nowadays, the chance of discovering the best antibody candidates for predicting clinical malaria has notably increased due to the availability of multi-sera data. The analysis of these data is typically divided into a feature selection phase followed by a predictive one where several models are constructed for predicting the outcome of interest. A key question in the analysis is to determine which antibodies should be included in the predictive stage and whether they should be included in the original or a transformed scale (i.e. binary/dichotomized).
الوصف (مترجم): Grant ref.: PPN/ULM/2020/1/00069/U/00001
نوع الوثيقة: journal article
وصف الملف: application/pdf
اللغة: English
العلاقة: 1756-0381
DOI: 10.1186/s13040-024-00354-4
الإتاحة: http://hdl.handle.net/10400.1/20396Test
حقوق: open access
رقم الانضمام: rcaap.com.ualg.sapientia.ualg.pt.10400.1.20396
قاعدة البيانات: RCAAP