التفاصيل البيبلوغرافية
| العنوان: |
Peptidoglycan synthesis and penicillin resistance in Streptococcus pneumoniae |
| المؤلفون: |
Narciso, Ana Rita da Cruz |
| المساهمون: |
Filipe, Sérgio Raposo, RUN |
| سنة النشر: |
2018 |
| مصطلحات موضوعية: |
penicillin resistance, Streptococcus pneumoniae, Biology |
| الوصف: |
"Resistance to penicillin in Streptococcus pneumoniae involves remodelling of penicillin-binding proteins (PBPs), enzymes involved in the last stages of peptidoglycan (PGN) synthesis, which reduce the affinity of these targets to the antibiotic. However, the peptidoglycan composition has an important role in the expression of resistance to this antibiotic. The murMN operon in particular seems to play a critical role, since deletion lead to the complete abolishment of penicillin resistance, even in the presence of the remodelled PBPs. (...)" |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| الإتاحة: |
http://hdl.handle.net/10362/94060Test |
| حقوق: |
open access |
| رقم الانضمام: |
rcaap.com.unl.run.unl.pt.10362.94060 |
| قاعدة البيانات: |
RCAAP |
