المؤلفون: Cavadas, Miguel, Oikonomidi, Ioanna, Gaspar, Catarina J., Burbridge, Emma, Badenes, Marina, Félix, Inês, Bolado, Alfonso, Hu, Tianyi, Bileck, Andrea, Gerner, Christopher, Domingos, Pedro M., von Kriegsheim, Alex, Adrain, Colin

المساهمون: Instituto de Tecnologia Química e Biológica António Xavier (ITQB), Molecular, Structural and Cellular Microbiology (MOSTMICRO), RUN

مصطلحات موضوعية: 14-3-3, ADAM metalloproteases, ADAM17/TACE, ectodomain shedding, EGFR, iRhom2, MAP kinases, TNF, Biochemistry, Genetics and Molecular Biology(all)

وصف الملف: application/pdf

العلاقة: 2211-1247; PURE: 4049853

الإتاحة: http://hdl.handle.net/10362/92266Test

المؤلفون: Oikonomidi, Ioanna, Burbridge, Emma, Cavadas, Miguel, Sullivan, Graeme, Collis, Blanka, Naegele, Heike, Clancy, Danielle, Brezinova, Jana, Hu, Tianyi, Bileck, Andrea, Gerner, Christopher, Bolado, Alfonso, Kriegsheim, Alex Von, Martin, Seamus J., Steinberg, Florian

المساهمون: ARCA

مصطلحات موضوعية: iTAP, IRhom interactor, TACE, TNF

وصف الملف: application/pdf

الإتاحة: http://hdl.handle.net/10400.7/912Test

المؤلفون: Cavadas, Miguel, Oikonomidi, Ioanna, Gaspar, Catarina J., Burbridge, Emma, Badenes, Marina, Félix, Inês, Bolado, Alfonso, Hu, Tianyi, Bileck, Andrea, Gerner, Christopher, Domingos, Pedro M., von Kriegsheim, Alex, Adrain, Colin

المساهمون: ARCA

مصطلحات موضوعية: ADAM metalloproteases, ADAM17/TACE, iRhom2, 14-3-3, MAP kinases, TNF, EGFR, ectodomain shedding

وصف الملف: application/pdf

العلاقة: Miguel Cavadas, Ioanna Oikonomidi, Catarina J. Gaspar, Emma Burbridge, Marina Badenes, Inês Félix, Alfonso Bolado, Tianyi Hu, Andrea Bileck, Christopher Gerner, Pedro M. Domingos, Alex von Kriegsheim, Colin Adrain, Phosphorylation of iRhom2 Controls Stimulated Proteolytic Shedding by the Metalloprotease ADAM17/TACE, In Cell Reports, Volume 21, Issue 3, 2017, Pages 745-757, ISSN 2211-1247, https://doi.org/10.1016/j.celrep.2017.09.074Test. (http://www.sciencedirect.com/science/article/pii/S2211124717313797Test) Keywords: ADAM metalloproteases; ADAM17/TACE; iRhom2; 14-3-3; MAP kinases; TNF; EGFR; ectodomain shedding

الإتاحة: http://hdl.handle.net/10400.7/794Test

المؤلفون: Cavadas, Miguel, Oikonomidi, Ioanna, Gaspar, Catarina J., Burbridge, Emma, Badenes, Marina, Félix, Inês, Bolado, Alfonso, Hu, Tianyi, Bileck, Andrea, Gerner, Christopher, Domingos, Pedro M., von Kriegsheim, Alex, Adrain, Colin

المساهمون: ARCA

مصطلحات موضوعية: 14-3-3 Proteins, ADAM17 Protein, Animals, Carrier Proteins, Cell Membrane, Endoplasmic Reticulum, HEK293 Cells, Humans, Mice, Knockout, Mitogen-Activated Protein Kinases, Phosphorylation, Phosphoserine, Signal Transduction, Substrate Specificity, Toll-Like Receptors, Proteolysis

وصف الملف: application/pdf

الإتاحة: http://hdl.handle.net/10400.7/911Test