نتائج البحث - "pharmacology: Insulin"

1

The Parkinson’s disease-linked Leucine-rich repeat kinase 2 (LRRK2) is required for insulin-stimulated translocation of GLUT4

المؤلفون: Wolfgang Wurst, Thomas Ott, Kathrin Brockmann, Daniela Vogt-Weisenhorn, Andrea Wenninger-Weinzierl, Marita Munz, Ralf Kühn, Saskia Biskup, Florian Giesert, Natalja Funk, Thomas Gasser

المصدر: Scientific Reports, Vol 9, Iss 1, Pp 1-16 (2019)
Scientific reports 9(1), 4515 (2019). doi:10.1038/s41598-019-40808-y
Scientific Reports

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, drug effects [Neuronal Outgrowth], metabolism [Leucine-Rich Repeat Serine-Threonine Protein Kinase-2], lcsh:Medicine, pharmacology [Fibroblast Growth Factors], Mice, 0302 clinical medicine, cytology [Fibroblasts], Insulin, Phosphorylation, lcsh:Science, pharmacology [Insulin], Glucose Transporter Type 4, Multidisciplinary, Kinase, Parkinson Disease, LRRK2, metabolism [rab GTP-Binding Proteins], Cell biology, ddc, Intracellular signal transduction, metabolism [Proto-Oncogene Proteins c-akt], Signal transduction, Technology Platforms, metabolism [Fibroblasts], Signal Transduction, drug effects [Signal Transduction], Cell Survival, drug effects [Cell Survival], Neuronal Outgrowth, metabolism [Parkinson Disease], Biology, Leucine-rich repeat, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, Polymorphism, Single Nucleotide, Article, 03 medical and health sciences, Animals, Humans, Protein kinase B, lcsh:R, Fibroblasts, metabolism [Glucose Transporter Type 4], pathology [Parkinson Disease], Rats, nervous system diseases, Fibroblast Growth Factors, 030104 developmental biology, rab GTP-Binding Proteins, biology.protein, genetics [Leucine-Rich Repeat Serine-Threonine Protein Kinase-2], lcsh:Q, Proto-Oncogene Proteins c-akt, ddc:600, 030217 neurology & neurosurgery, GLUT4

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e9ccd730fe7023ec1eb8e959bc4ec6fTest
http://link.springer.com/article/10.1038/s41598-019-40808-yTest

2

Insulin growth factor binding protein 7 is a novel target to treat dementia

المؤلفون: Ivana Delalle, Roberto Carlos Agis-Balboa, Hope Y Agbemenyah, Susanne Burkhardt, Andre Fischer

المصدر: Neurobiology of disease 62, 135-143 (2014). doi:10.1016/j.nbd.2013.09.011
Neurobiology of Disease, Vol 62, Iss, Pp 135-143 (2014)

مصطلحات موضوعية: IGFBP7, Regulator, Hippocampus, metabolism [Hippocampus], Mice, Transgenic, Insulin-like growth factor-binding protein, Learning and memory, lcsh:RC321-571, insulin-like growth factor binding protein-related protein 1, Mice, 03 medical and health sciences, drug effects [Memory], 0302 clinical medicine, Alzheimer Disease, Memory, ddc:570, drug effects [Behavior, Animal], medicine, Animals, Humans, Dementia, metabolism [Dementia], lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, 030304 developmental biology, genetics [Insulin-Like Growth Factor Binding Proteins], 0303 health sciences, Behavior, Animal, biology, DNA Methylation, medicine.disease, 3. Good health, Associative learning, Insulin-Like Growth Factor Binding Proteins, Mice, Inbred C57BL, Disease Models, Animal, Neurology, pharmacology [Insulin-Like Growth Factor Binding Proteins], metabolism [Insulin-Like Growth Factor Binding Proteins], Alzheimer, biology.protein, Epigenetics, Memory consolidation, Alzheimer's disease, Psychology, Neuroscience, metabolism [Alzheimer Disease], 030217 neurology & neurosurgery

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a426254e62e02e39de9d9f5455d843b1Test
https://doi.org/10.1016/j.nbd.2013.09.011Test

3

Profiling of circulating microRNAs reveals common microRNAs linked to type 2 diabetes that change with insulin sensitization

المؤلفون: Sophie Rome, Oscar Rovira, José María Moreno-Navarrete, Eduardo Esteve, Jennifer Rieusset, Gemma Xifra, Francisco J. Ortega, José Manuel Fernández-Real, Josep M. Mercader, Ester Guerra, Wifredo Ricart, Marek Straczkowski, Monika Karczewska-Kupczewska, Cristina Martínez

المساهمون: Cardiovasculaire, métabolisme, diabétologie et nutrition (CarMeN), Institut National de la Recherche Agronomique (INRA)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM), Hospices Civils de Lyon (HCL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National des Sciences Appliquées de Lyon (INSA Lyon), Institut National des Sciences Appliquées (INSA)-Université de Lyon-Institut National des Sciences Appliquées (INSA)-Université de Lyon-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Institut National de la Recherche Agronomique (INRA), Programme Innovative Economy [UDA-POIG.01.03.01-00-128/08], European Union within the European Regional Development Fund, Spanish Ministry of Science and Innovation [FIS 2011-00214], CIBER de la Fisiopatologia de la Obesidad y la Nutricion (CIBERobn), Associacio Catalana de Diabetis, Sara Borrell fellowship, ISCIII, Université de Lyon-Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Hospices Civils de Lyon (HCL)

المصدر: Diabetes Care
Diabetes Care, American Diabetes Association, 2014, 37 (5), pp.1375-1383. ⟨10.2337/dc13-1847⟩

مصطلحات موضوعية: Male, endocrine system diseases, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, [SDV]Life Sciences [q-bio], administration & dosage, Pilot Projects, pharmacology"*"Insulin Resistance, Type 2 diabetes, 0302 clinical medicine, Insulin, Sensitization, 0303 health sciences, Heparin, Middle Aged, Metformin, drug therapy, medicine.anatomical_structure, genetics"*"Male"*"Metformin, Female, Type 2, medicine.drug, Adult, medicine.medical_specialty, Adolescent, 030209 endocrinology & metabolism, Adolescent"*"Adult"*"Aged"*"Biological Markers/metabolism"*"Cross-Sectional Studies"*"Diabetes Mellitus, metabolism"*"Middle Aged"*"Pilot Projects"*"Young Adult, 03 medical and health sciences, Young Adult, Insulin resistance, therapeutic use"*"MicroRNAs, Double-Blind Method, blood, Diabetes mellitus, Internal medicine, Internal Medicine, medicine, Humans, Hypoglycemic Agents, Type 2/blood/drug therapy/*genetics"*"Double-Blind Method"*"Female"*"Humans"*"Hypoglycemic Agents/administration & dosage/pharmacology"*"Insulin/administration & dosage/pharmacology"*"Insulin Resistance/*genetics"*"Male"*"Metformin/therapeutic use"*"MicroRNAs/*metabolism"*"Middle Aged"*"Pilot Projects"*"Young Adult, 030304 developmental biology, Aged, Advanced and Specialized Nursing, business.industry, pharmacology"*"Insulin, medicine.disease, Circulating MicroRNA, MicroRNAs, Endocrinology, Cross-Sectional Studies, Diabetes Mellitus, Type 2, genetics"*"Double-Blind Method"*"Female"*"Humans"*"Hypoglycemic Agents, Insulin Resistance, business, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1a38e0f19ac363323dc70fa330547a2Test
https://hal.archives-ouvertes.fr/hal-01859430Test

4

Non-invasive imaging of endogenous neural stem cell mobilization in vivo using Positron Emission Tomography

المؤلفون: Heiko Backes, Roland T. Ullrich, Michael Schroeter, Beata Emig, Marie-Lune Simard, Bernd Neumaier, Rudolf Graf, Mathias Hoehn, Gereon R. Fink, Maria Adele Rueger, Maureen Walberer

المصدر: The journal of neuroscience 30, 6454-6460 (2010). doi:10.1523/JNEUROSCI.6092-09.2010

مصطلحات موضوعية: Pathology, pharmacology [Fibroblast Growth Factor 2], metabolism [Stem Cells], Hippocampus, Endogeny, Brain Ischemia, ddc:590, Cell Movement, Lateral Ventricles, physiology [Stem Cells], Insulin, alovudine, drug effects [Cell Movement], Cells, Cultured, pharmacology [Insulin], Neurons, pharmacology [Membrane Proteins], medicine.diagnostic_test, drug effects [Lateral Ventricles], Chemistry, Stem Cells, General Neuroscience, methods [Positron-Emission Tomography], Intracellular Signaling Peptides and Proteins, Brain, Articles, physiology [Neurons], physiopathology [Brain Ischemia], Neural stem cell, medicine.anatomical_structure, metabolism [Neurons], Positron emission tomography, metabolism [Dideoxynucleosides], drug effects [Brain], Fibroblast Growth Factor 2, physiology [Cell Movement], Noninvasive imaging, medicine.medical_specialty, metabolism [Brain Ischemia], Ischemia, Subventricular zone, Biology, physiology [Brain], embryology [Brain], In vivo, Physiology (medical), medicine, Animals, delta protein, Cell Proliferation, drug effects [Cell Proliferation], physiology [Lateral Ventricles], Dentate gyrus, Membrane Proteins, medicine.disease, Dideoxynucleosides, Rats, metabolism [Brain], Positron-Emission Tomography, radionuclide imaging [Brain], Neurology (clinical), Neuroscience

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fadd03a17aee8d9dd4b44dde8041b758Test
https://doi.org/10.1055/s-0032-1301486Test

5

Effects of Short and Prolonged Mild Intracellular Nitric Oxide Manipulations on Various Aspects of Insulin Secretion in INS-1E beta-Cells

المؤلفون: Eleuterio Ferrannini, Enzo Nisoli, Simona Baldi, Alberto Tulipani, Andrea Delbarba, Elena Venturi, Eleonora Santini, Andrea Natali

مصطلحات موضوعية: Intracellular Fluid, medicine.medical_specialty, insulin secretion, Time Factors, mitochondrial biogenesis, Arginine, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Cells, Hydroxylamine, Biology, Pharmacology, Nitric oxide, Dose-Response Relationship, chemistry.chemical_compound, nitric oxide, Endocrinology, Internal medicine, Insulin-Secreting Cells, Internal Medicine, medicine, Animals, Insulin, Secretion, Nitric Oxide Donors, Animals, Arginine, pharmacology, Cells, Cultured, Dose-Response Relationship, Drug, Glucose, pharmacology, Hydroxylamine, pharmacology, Insulin, pharmacology/secretion, Insulin-Secreting Cells, drug effects/metabolism/physiology, Intracellular Fluid, drug effects/metabolism, Mitochondria, drug effects/metabolism/physiology, NG-Nitroarginine Methyl Ester, pharmacology, Nitric Oxide Donors, pharmacology, Nitric Oxide, metabo/lism, Rats, Time Factors, Receptor, Cells, Cultured, drug effects/metabolism/physiology, Cultured, Dose-Response Relationship, Drug, General Medicine, TFAM, Mitochondria, Rats, Glucose, NG-Nitroarginine Methyl Ester, metabo/lism, Mitochondrial biogenesis, chemistry, pharmacology, Drug, drug effects/metabolism, pharmacology/secretion, Intracellular

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cdbf1c1c6376668e7464f5fe0dd74fbTest
http://hdl.handle.net/11568/152900Test

6

Thyroid hormone, insulin, and glucocorticoids are sufficient to support chondrocyte differentiation to hypertrophy: a serum-free analysis

المؤلفون: Ranieri Cancedda, Beatrice Dozin, Rodolfo Quarto, Giuliano Campanile

المصدر: The Journal of Cell Biology

مصطلحات موضوعية: medicine.medical_specialty, Cell Survival, Cells, Cellular differentiation, medicine.medical_treatment, Type II collagen, Chick Embryo, Cartilage metabolism, Biology, Culture Media, Serum-Free, Dexamethasone, Chondrocyte, Serum-Free, Internal medicine, medicine, Animals, Insulin, Alkaline Phosphatase, metabolism, Animals, Cartilage, cytology/drug effects/metabolism, Cell Differentiation, drug effects, Cell Survival, drug effects, Cells, Cultured, Chick Embryo, Collagen, biosynthesis, Culture Media, Serum-Free, Dexamethasone, pharmacology, Insulin, pharmacology, Triiodothyronine, pharmacology, Cells, Cultured, Cultured, Cell Differentiation, Articles, cytology/drug effects/metabolism, Cell Biology, Ascorbic acid, Chondrogenesis, Culture Media, Cartilage, medicine.anatomical_structure, Endocrinology, drug effects, Triiodothyronine, Collagen, biosynthesis, metabolism, Type I collagen

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0eb0db9483edd6600d003ae7a204137aTest
https://doi.org/10.1083/jcb.119.4.989Test

7

Insulin, insulin-like growth factor I (IGF-I) and IGF-II enhance basal and gonadotrophin-releasing hormone-stimulated luteinizing hormone release from rat anterior pituitary cells in vitro

المؤلفون: Angelo Cagnacci, Renza Soldani, Samuel Sc Yen

المصدر: European journal of endocrinology. 131(6)

مصطلحات موضوعية: Male, medicine.medical_specialty, medicine.drug_class, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Cells, Gonadotropin-releasing hormone, Biology, Peptide hormone, Gonadotropic cell, Gonadotropin-Releasing Hormone, Rats, Sprague-Dawley, Insulin-like growth factor, Endocrinology, Anterior pituitary, Insulin-Like Growth Factor II, Pituitary Gland, Anterior, Internal medicine, medicine, Animals, Insulin, Insulin-Like Growth Factor I, Pancreatic hormone, Cells, Cultured, Anterior, cytology/metabolism, Cultured, General Medicine, Luteinizing Hormone, Animals, Cells, Cultured, Gonadotropin-Releasing Hormone, pharmacology, Insulin, pharmacology, Insulin-Like Growth Factor I, pharmacology, Insulin-Like Growth Factor II, pharmacology, Luteinizing Hormone, metabolism, Male, Pituitary Gland, cytology/metabolism, Rats, Rats, Sprague-Dawley, Rats, medicine.anatomical_structure, Pituitary Gland, Gonadotropin, pharmacology, Luteinizing hormone, metabolism

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::657afde427071978c7880a026818245aTest
https://pubmed.ncbi.nlm.nih.gov/7804448Test

8

Alpha-adrenergic system in the modulation of pancreatic A and B cell function in normal rats

المؤلفون: Paolo Filipponi, Carla Mannarelli, F Gregorio, Romeo Pippi, Fausto Santeusanio, Ildo Nicoletti, Celestino Ferrandina

المصدر: Diabetes Research and Clinical Practice. 2:325-336

مصطلحات موضوعية: Male, medicine.medical_specialty, alpha, Epinephrine, Adrenergic receptor, Endocrinology, Diabetes and Metabolism, Inbred Strains, Adrenergic, Biology, Arginine, Glucagon, Islets of Langerhans, Endocrinology, Internal medicine, Insulin Secretion, Receptors, Internal Medicine, Prazosin, medicine, Animals, Insulin, drug effects/secretion, Receptor, Adrenergic alpha-Antagonists, Rats, Inbred Strains, General Medicine, Receptors, Adrenergic, alpha, Rats, Yohimbine, secretion, Glucose, Adrenergic alpha-Agonists, physiology, pharmacology, Adrenergic alpha-Antagonists, pharmacology, Animals, Arginine, pharmacology, Epinephrine, pharmacology, Glucagon, secretion, Glucose, pharmacology, Insulin, secretion, Islets of Langerhans, drug effects/secretion, Male, Rats, Rats, Inbred Strains, Receptors, pharmacology, medicine.drug

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5625034680f6b33ef63e506adcb5655dTest
https://doi.org/10.1016/s0168-8227Test(86)80069-9

9

Selective impairment of pancreatic A cell suppression by glucose during acute alloxan-induced insulinopenia: in vitro study on isolated perfused rat pancreas

المؤلفون: Filipponi, P., Gregorio, F., Cristallini, S., Ferrandina, C., Nicoletti, Ildo, Santeusanio, Fausto

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=od______3982::1903117f0aba3c5f5110ab3b3337c3efTest
http://hdl.handle.net/11391/918603Test

10

Insulin enhances endothelial α2-adrenergic vasorelaxation by a pertussis toxin mechanism

المؤلفون: Francesco Monti, Guido Iaccarino, Emanuele Barbato, Bruno Trimarco, Carmine Vecchione, Carmine Morisco, Lucia Parrella, Giuseppe Lembo

المساهمون: Lembo, G, Iaccarino, G, Vecchione, C, Barbato, Emanuele, Morisco, Carmine, Monti, F, Parrella, L, Trimarco, Bruno, Lembo, G., Iaccarino, G., Vecchione, C., Barbato, E., Morisco, C., Monti, F., Parrella, L., Trimarco, B.

المصدر: Scopus-Elsevier

مصطلحات موضوعية: Male, Arginine, Bordetella, medicine.medical_treatment, Rats, Inbred WKY, chemistry.chemical_compound, Rats, Inbred SHR, Receptors, Citrulline, Insulin, Virulence Factors, Bordetella, Enzyme Inhibitors, endotelio, ossido nitrico, insulino-resistenza, Aorta, Vasodilation, medicine.anatomical_structure, Adrenergic, Brimonidine Tartrate, Ionomycin, Adrenergic alpha-Agonists, pharmacology, Animals, Aorta, cytology/drug effects/physiology, Endothelium, Vascular, cytology/drug effects/physiology, Enzyme Inhibitors, pharmacology, Insulin, pharmacology, Male, Pertussis Toxin, Quinoxalines, pharmacology, Rats, Rats, Inbred SHR, Rats, Inbred WKY, Receptors, alpha, physiology, Vasodilation, drug effects/physiology, Virulence Factors, pharmacology, omega-N-Methylarginine, pharmacology, Acetylcholine, medicine.drug, medicine.medical_specialty, Inbred SHR, Endothelium, Virulence Factors, In Vitro Techniques, Biology, Pertussis toxin, Insulin resistance, Quinoxalines, Internal medicine, Internal Medicine, medicine, Animals, Inbred WKY, omega-N-Methylarginine, Receptors, Adrenergic, alpha, medicine.disease, Rats, drug effects/physiology, Endocrinology, Pertussis Toxin, chemistry, physiology, cytology/drug effects/physiology, Endothelium, Vascular

وصف الملف: STAMPA

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96c546b9072eb185f6fa346a21f35fbcTest
http://www.scopus.com/inward/record.url?eid=2-s2.0-0030708755&partnerID=MN8TOARSTest

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