المؤلفون: Vogelstein, Joshua T., Powell, Michael, Koenecke, Allison, Xiong, Ruoxuan, Fischer, Nicole, Huq, Sakibul, Khalafallah, Adham M., Caffo, Brian, Stuart, Elizabeth A., Papadopoulos, Nickolas, Kinzler, Kenneth W., Vogelstein, Bert, Zhou, Shibin, Bettegowda, Chetan, Konig, Maximilian F., Mensh, Brett, Athey, Susan

المصدر: Dimensions

مصطلحات موضوعية: TISSUES AND ORGANS, COVID-19, SARS-COV-2, SEVERE ACUTE RESPIRATORY SYNDROME CORONAVIRUS 2, QUANTITATIVE METHODS

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010a448a88fb8cfb43c54ab96c0fa201Test

المؤلفون: Cromm, Philipp M., Crews, Craig M., Mainolfi, Nello, Rasmusson, Tim, Poulikakos, Poulikos I., Zhang, Chao, Bollag, Gideon, Shokat, Kevan M., Rosen, Neal, Agianian, Bogos, Gavathiotis, Evripidis, Raina, Kanak, Durrant, David E., Morrison, Deborah K., Neklesa, Taavi K., Winkler, James D., Chang, F., Steelman, L. S., Lee, J. T., Shelton, J. G., Navolanic, P. M., Blalock, W. L., Franklin, R. A., McCubrey, J. A., Burslem, George M., Smith, Blake E., Lai, Ashton C., Jaime-Figueroa, Saul, McQuaid, Daniel C., Bondeson, Daniel P., Toure, Momar, Dong, Hanqing, Qian, Yimin, Wang, Jing, Crew, Andrew P., Hines, John, Sanchez, Jaquelyn N., Wang, Ton, Cohen, Mark S., Shelledy, PharmD, Lindsay, Roman, PharmD, BCOP, Danielle, Davies, Helen, Bignell, Graham R., Cox, Charles, Stephens, Philip, Edkins, Sarah, Clegg, Sheila, Teague, Jon, Woffendin, Hayley, Garnett, Mathew J., Bottomley, William, Davis, Neil, Dicks, Ed, Ewing, Rebecca, Floyd, Yvonne, Gray, Kristian, Hall, Sarah, Hawes, Rachel, Hughes, Jaime, Kosmidou, Vivian, Menzies, Andrew, Mould, Catherine, Parker, Adrian, Stevens, Claire, Watt, Stephen, Hooper, Steven, Jayatilake, Hiran, Gusterson, Barry A., Cooper, Colin, Shipley, Janet, Hargrave, Darren, Pritchard-Jones, Katherine, Maitland, Norman, Chenevix-Trench, Georgia, Riggins, Gregory J., Bigner, Darell D., Palmieri, Giuseppe, Cossu, Antonio, Flanagan, Adrienne, Nicholson, Andrew, Ho, Judy W.C., Leung, Suet Y., Yuen, Siu T., Weber, Barbara L., Seigler, Hilliard F., Darrow, Timothy L., Paterson, Hugh, Wooster, Richard, Stratton, Michael R., Futreal, P. Andrew, Spevak, Wayne, Zhang, Ying, Burton, Elizabeth A., Ma, Yan, Habets, Gaston, Zhang, Jiazhong, Lin, Jack, Ewing, Todd, Matusow, Bernice, Tsang, Garson, Marimuthu, Adhirai, Cho, Hanna, Wu, Guoxian, Wang, Weiru, Fong, Daniel, Nguyen, Hoa, Shi, Songyuan, Womack, Patrick, Nespi, Marika, Shellooe, Rafe, Carias, Heidi, Powell, Ben, Light, Emily, Sanftner, Laura, Walters, Jason, Tsai, James, West, Brian L., Visor, Gary, Rezaei, Hamid, Lin, Paul S., Nolop, Keith, Ibrahim, Prabha N., Hirth, Peter, Arozarena, Imanol, Wellbrock, Claudia, Samatar, Ahmed A., Karoulia, Zoi, Chapman, Paul B., Hauschild, Axel, Robert, Caroline, Haanen, John B., Ascierto, Paolo, Larkin, James, Dummer, Reinhard, Garbe, Claus, Testori, Alessandro, Maio, Michele, Hogg, David, Lorigan, Paul, Lebbe, Celeste, Jouary, Thomas, Schadendorf, Dirk, Ribas, Antoni, O'Day, Steven J., Sosman, Jeffrey A., Kirkwood, John M., Eggermont, Alexander M.M., Dreno, Brigitte, Li, Jiang, Nelson, Betty, Hou, Jeannie, Lee, Richard J., Flaherty, Keith T., McArthur, Grant A., Vogelstein, Bert, Papadopoulos, Nickolas, Velculescu, Victor E., Zhou, Shibin, Diaz, Luis A., Kinzler, Kenneth W., Millington, G. W.M., Buhimschi, Alexandru D., Hamman, Brian D., Ishchenko, Alexey

المصدر: Cromm, P M, Crews, C M, Mainolfi, N, Rasmusson, T, Poulikakos, P I, Zhang, C, Bollag, G, Shokat, K M, Rosen, N, Crews, C M, Agianian, B, Gavathiotis, E, Raina, K, Crews, C M, Durrant, D E, Morrison, D K, Neklesa, T K, Winkler, J D, Crews, C M, Chang, F, Steelman, L S, Lee, J T, Shelton, J G, Navolanic, P M, Blalock, W L, Franklin, R A, McCubrey, J A, Burslem, G M, Smith, B E, Lai, A C, Jaime-Figueroa, S, McQuaid, D C, Bondeson, D P, Toure, M, Dong, H, Qian, Y, Wang, J, Crew, A P, Hines, J, Crews, C M, Sanchez, J N, Wang, T, Cohen, M S, Shelledy, PharmD, L, Roman, PharmD, BCOP, D, Davies, H, Bignell, G R, Cox, C, Stephens, P, Edkins, S, Clegg, S, Teague, J, Woffendin, H, Garnett, M J, Bottomley, W, Davis, N, Dicks, E, Ewing, R, Floyd, Y, Gray, K, Hall, S, Hawes, R, Hughes, J, Kosmidou, V, Menzies, A, Mould, C, Parker, A, Stevens, C, Watt, S, Hooper, S, Jayatilake, H, Gusterson, B A, Cooper, C, Shipley, J, Hargrave, D, Pritchard-Jones, K, Maitland, N, Chenevix-Trench, G, Riggins, G J, Bigner, D D, Palmieri, G, Cossu, A, Flanagan, A, Nicholson, A, Ho, J W C, Leung, S Y, Yuen, S T, Weber, B L, Seigler, H F, Darrow, T L, Paterson, H, Wooster, R, Wooster, R, Stratton, M R, Futreal, P A, Zhang, C, Spevak, W, Zhang, Y, Burton, E A, Ma, Y, Habets, G, Zhang, J, Lin, J, Ewing, T, Matusow, B, Tsang, G, Marimuthu, A, Cho, H, Wu, G, Wang, W, Fong, D, Nguyen, H, Shi, S, Womack, P, Nespi, M, Shellooe, R, Carias, H, Powell, B, Light, E, Sanftner, L, Walters, J, Tsai, J, West, B L, Visor, G, Rezaei, H, Lin, P S, Nolop, K, Ibrahim, P N, Hirth, P, Bollag, G, Arozarena, I, Wellbrock, C, Samatar, A A, Poulikakos, P I, Karoulia, Z, Gavathiotis, E, Poulikakos, P I, Chapman, P B, Hauschild, A, Robert, C, Haanen, J B, Ascierto, P, Larkin, J, Dummer, R, Garbe, C, Testori, A, Maio, M, Hogg, D, Lorigan, P, Lebbe, C, Jouary, T, Schadendorf, D, Ribas, A, O'Day, S J, Sosman, J A, Kirkwood, J M, Eggermont, A M M, Dreno, B, Nolop, K, Li, J, Nelson, B, Hou, J, Lee, R J, Flaherty, K T, McArthur, G A, Vogelstein, B, Papadopoulos, N, Velculescu, V E, Zhou, S, Diaz, L A, Kinzler, K W, Millington, G W M, Bondeson, D P, Smith, B E, Burslem, G M, Buhimschi, A D, Hines, J, Jaime-Figueroa, S, Wang, J, Hamman, B D, Ishchenko, A & Crews, C M 2018, ' The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study ', Cell Chemical Biology, pp. 67-77.e3 . https://doi.org/10.1016/j.chembiol.2017.09.009Test

مصطلحات موضوعية: 0301 basic medicine, Small molecular weight membrane-permeable inhibito, MAPK/p38, selective degradation, Raf kinases, Clinical Biochemistry, Receptor Protein-Tyrosine Kinases, protein-protein interactions, Signal transduction, Ligands, ERK cascade, protein dimerisation, Biochemistry, ternary complex, Receptor tyrosine kinase, Therapeutic intervention, 0302 clinical medicine, PROTACs, Drug Discovery, Kinome, Enzyme Inhibitors, Cereblon, E3 ligase, SNIPER, receptor tyrosine kinases, Manchester Cancer Research Centre, biology, Ras pathway, targeted degradation, Ubiquitin ligase, Raf inhibitors, 030220 oncology & carcinogenesis, Cytokines, cancer therapy, Molecular Medicine, Protein family, Ubiquitin-Protein Ligases, EGFR, hydrophobic tagging, Undruggable proteome, chemical biology, Protein degradation, Article, PROTAC, 03 medical and health sciences, proteomics, HER2, VHL, Humans, Molecular Biology, c-Met, Pharmacology, Heterobifunctional degrader, ResearchInstitutes_Networks_Beacons/mcrc, Proteolysis targeting chimera, Ubiquitination, Oncogenes, 030104 developmental biology, MAPK kinase cascade, CRBN, Proteolysis, biology.protein, Targeted protein degradation

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::361df2b1e3e643d7e80d0d128cb88ce3Test
https://doi.org/10.1016/j.chembiol.2017.09.009Test

المؤلفون: Perica, Karlo, Bieler, Joan Glick, Schütz, Christian, Varela, Juan Carlos, Douglass, Jacqueline, Skora, Andrew, Chiu, Yen Ling, Oelke, Mathias, Kinzler, Kenneth, Zhou, Shibin, Vogelstein, Bert, Schneck, Jonathan P.

مصطلحات موضوعية: Adoptive cell transfer, medicine.medical_treatment, T cell, Adoptive immunotherapy, General Physics and Astronomy, Antigen-Presenting Cells, Cell Separation, Biology, Adaptive Immunity, Article, Mice, Artificial antigen presenting cells, Antigen, In vivo, Antigens, Neoplasm, Cell Line, Tumor, medicine, Animals, Humans, General Materials Science, Cells, Cultured, General Engineering, Immunotherapy, In vitro, Cell biology, Mice, Inbred C57BL, medicine.anatomical_structure, Immunology, Nanoparticles

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd54edb01bb095f77e503bc20a968d4eTest
https://europepmc.org/articles/PMC5082131Test/

المؤلفون: Liu, Guanshu, Bettegowda, Chetan, Qiao, Yuan, Staedtke, Verena, Chan, Kannie W.Y., Bai, Renyuan, Li, Yuguo, Riggins, Gregory J., Kinzler, Kenneth W., Bulte, Jeff W.M., McMahon, Michael T., Gilad, Assaf A., Vogelstein, Bert, Zhou, Shibin, van Zijl, Peter C.M.

مصطلحات موضوعية: Clostridium, Mice, Inbred BALB C, Reproducibility of Results, Magnetic Resonance Imaging, Sensitivity and Specificity, Article, Biological Therapy, Mice, Cell Line, Tumor, Image Interpretation, Computer-Assisted, Clostridium Infections, Animals, Humans, Female, Colorectal Neoplasms

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::cc53e27b1e0d88d0ea15f5fd45514adeTest
https://europepmc.org/articles/PMC3857583Test/