المؤلفون: Minki Kim, Muhammad Irfan, Man Hee Rhee

المصدر: Journal of Ginseng Research, Vol 44, Iss 1, Pp 24-32 (2020)
Journal of Ginseng Research

مصطلحات موضوعية: 0301 basic medicine, MKK4, mitogen-activated protein kinase kinase 4, Ginsenosides, Syk, spleen tyrosine kinase, PPD, protopanaxadiol, AA, arachidonic acid, Review, vWF, von Willebrand factor, Pharmacology, ERK, extracellular signal–regulated kinase, chemistry.chemical_compound, Ginseng, 0302 clinical medicine, MLC, myosin light chain, lcsh:Botany, Medicine, PAR, proteinase-activated receptor, TS, total saponin, AC, adenylyl cyclase, media_common, GPVI, glycoprotein VI, [Ca2+]i, intracellular calcium ion, PI3K, phosphatidylinositol 3-kinase, lcsh:QK1-989, cAMP, cyclic adenosine monophosphate, IC50, half maximal (50%) inhibitory concentration, Ginsenoside, 030220 oncology & carcinogenesis, IP3, inositol-1,4,5-triphosphate, JNK, c-Jun N-terminal kinase, Nutraceutical, Biotechnology, Drug, Korean ginseng, ATP, adenosine triphosphate, media_common.quotation_subject, CRP, collagen-related peptide, aPTT, activated partial thromboplastin time, Biochemistry, Genetics and Molecular Biology (miscellaneous), World health, 03 medical and health sciences, PT, prothrombin time, PKC, protein kinase C, Antiplatelet, TxAS, thromboxane-A synthase, Platelet activation, ASA, acetylsalicylic acid, PAF, platelet-activating factor, TxB2, thromboxane B2, business.industry, cPLA2α, cytosolic phospholipase A2α, PLA2, phospholipase A2, Synergism, TxA2, thromboxane A2, PPT, protopanaxatriol, Anti platelet, ADP, adenosine diphosphate, COX, cyclooxygenase, 030104 developmental biology, CSF, crude saponin fraction, Complementary and alternative medicine, chemistry, ROCK, Rho-associated protein kinase, Structural modification, TxR, thromboxane receptor, Akt, protein kinase B, PLCγ2, phospholipase C gamma-2, PKG, protein kinase G, SFK, Src family kinase, PKA, protein kinase A, business, VASP, vasodilator-stimulated phosphoprotein, MAPK, mitogen-activated protein kinase

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77592e2f7358ae138f91eeb44c16a0d7Test
http://www.sciencedirect.com/science/article/pii/S1226845319301332Test

المؤلفون: Nicolas Bisson, Frédérick A. Mallette, Laurence M. Gagné, Marc-Étienne Huot, Jean-Philippe Lambert, Nadine Morin, Noémie Lavoie

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: PTM, post-translational modification, mTORC1, Biochemistry, mTORC2, chemistry.chemical_compound, 0302 clinical medicine, EPHB2, Phosphorylation, CIP, calf intestinal alkaline phosphatase, 0303 health sciences, biology, mTOR, mechanistic target of rapamycin, TOR Serine-Threonine Kinases, mTORC2, mTOR complex 2, Intracellular Signaling Peptides and Proteins, IP, immunoprecipitation, 3. Good health, Cell biology, 030220 oncology & carcinogenesis, mTOR, Research Article, Signal Transduction, Fer, Feline sarcoma–related protein, DEPTOR, FRQS, Fonds de Recherche du Québec—Santé, R-2HG, R-2-hydroxyglutarate, SYK, spleen tyrosine kinase, 03 medical and health sciences, Humans, Molecular Biology, Protein kinase B, Mechanistic target of rapamycin, PI3K/AKT/mTOR pathway, 030304 developmental biology, tyrosine phosphorylation, EPH, erythropoietin-producing hepatocellular carcinoma, Tyrosine phosphorylation, Cell Biology, Tyr, tyrosine, PTEN, phosphatase and tensin homolog, HEK293 Cells, chemistry, biology.protein, β-TRCP1, β-transducin repeat–containing protein 1, Tyrosine, mTORC1, mTOR complex 1, Protein Processing, Post-Translational, HA, hemagglutinin, HeLa Cells

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f12996bbcdf1e104173be833b69be78Test
http://europepmc.org/articles/PMC8551655Test

المؤلفون: Frantisek Spoutil, Jarmila Králová, Tomas Brdicka, Nataliia Pavliuchenko, Jan Prochazka, Jana Pokorná, Radislav Sedlacek, Matej Fabisik, Kristyna Ilievova

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: IL-1β, interleukin-1β, Neutrophils, Interleukin-1beta, Syk, Protein tyrosine phosphatase, chronic recurrent multifocal osteomyelitis, Biology, PTPRC, Biochemistry, Severity of Illness Index, PSTPIP2, SYK, spleen tyrosine kinase, Mice, ROS, reactive oxygen species, FBS, fetal bovine serum, Immunoreceptor tyrosine-based activation motif, Animals, CD45, Tyrosine, Molecular Biology, Adaptor Proteins, Signal Transducing, Mice, Knockout, Toll-Like Receptors, ITAM, immunoreceptor tyrosine-based activation motif, Signal transducing adaptor protein, SFK, Src-family kinase, Osteomyelitis, Cell Biology, μCT, microcomputerized tomography, autoinflammation, CMO, chronic multifocal osteomyelitis, Cytoskeletal Proteins, Diabetes Mellitus, Type 1, Cancer research, biology.protein, Phosphorylation, LPS, lipopolysaccharide, Leukocyte Common Antigens, Tyrosine kinase, Research Article, Signal Transduction

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eef27166adbf2fe72aed1789b3ffd956Test
http://europepmc.org/articles/PMC8455366Test

المؤلفون: Mariano Prado Acosta, Guillaume Goyette-Desjardins, Jörg Scheffel, Anne Dudeck, Jürgen Ruland, Bernd Lepenies

المصدر: Frontiers in Immunology, Vol 12 (2021)

مصطلحات موضوعية: lcsh:Immunologic diseases. Allergy, Mincle, antigen presenting cell, Syk (spleen tyrosine kinase), lcsh:RC581-607, CARD9, Lactobacillus brevis, S-layer

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doajarticles::6b51342b6bf94d03a17e6fb60f4ce1f3Test
https://www.frontiersin.org/articles/10.3389/fimmu.2021.602067/fullTest

المؤلفون: Mariano, Prado Acosta, Guillaume, Goyette-Desjardins, Jörg, Scheffel, Anne, Dudeck, Jürgen, Ruland, Bernd, Lepenies

المصدر: Frontiers in Immunology

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Mice, Knockout, Membrane Glycoproteins, Mincle, Levilactobacillus brevis, Immunology, Antigen-Presenting Cells, Membrane Proteins, Bone Marrow Cells, Lactobacillus brevis, S-layer, CARD Signaling Adaptor Proteins, Mice, antigen presenting cell, Syk (spleen tyrosine kinase), Animals, Cytokines, Syk Kinase, Lectins, C-Type, CARD9, Signal Transduction, Original Research

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::8c2bf0ab25a41bddd6791c14b0911f80Test
https://pubmed.ncbi.nlm.nih.gov/33732234Test

المؤلفون: Matthias Epple, Yana Dautova, Kevin Pappert, Alexander N. Kapustin, Martin D. Bootman, Hanneke Okkenhaug, Diane Proudfoot, Simon J. Cook, Catherine M. Shanahan

المصدر: Journal of Molecular and Cellular Cardiology
Dautova, Y, Kapustin, A, Pappert, K, Epple, M, Okkenhaug, H, Cook, S J, Shanahan, C M, Bootman, M D & Proudfoot, D 2017, ' Calcium phosphate particles stimulate interleukin-1β release from human vascular smooth muscle cells : A role for spleen tyrosine kinase and exosome release ', Journal of Molecular and Cellular Cardiology . https://doi.org/10.1016/j.yjmcc.2017.12.007Test

مصطلحات موضوعية: 0301 basic medicine, Calcium Phosphates, Male, BM, basal culture medium, Vascular smooth muscle, Inflammasomes, Interleukin-1beta, Syk, Exosomes, Muscle, Smooth, Vascular, SYK, Phosphorylation, Cells, Cultured, Caspase 1, Inflammasome, Middle Aged, CaP, calcium phosphate, Cell biology, VSMC, vascular smooth muscle cells, Caspase-1, Cytokines, LPS, lipopolysaccharide, Female, Cardiology and Cardiovascular Medicine, medicine.drug, Adult, IL-1β, interleukin-1β, ATP, adenosine triphosphate, Myocytes, Smooth Muscle, Chemie, chemistry.chemical_element, Calcium, Exosome, MSU, monosodium urate, Article, SYK, spleen tyrosine kinase, 03 medical and health sciences, Young Adult, medicine, SFM, serum-free medium, Humans, Syk Kinase, Secretion, NLRP3: nucleotide-binding domain, leucine-rich repeat/pyrin domain-containing-3, Molecular Biology, Calcium phosphate particles, Enzyme Activation, 030104 developmental biology, chemistry

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d86e001074dcd1dcf16d9ed519a5db8Test
http://europepmc.org/articles/PMC5823844Test

المؤلفون: Edina Simon, Attila Mócsai, Dániel Csete, Zoltán Jakus, Petra Aradi, Dávid Győri, Szilvia Benkő, Ahmad Alatshan, Csaba Dobó-Nagy

المصدر: Frontiers in Immunology, Vol 10 (2019)
Frontiers in Immunology

مصطلحات موضوعية: 0301 basic medicine, musculoskeletal diseases, lcsh:Immunologic diseases. Allergy, VAV1, mice, Immunology, Cre recombinase, Syk, Mice, Transgenic, chemical and pharmacologic phenomena, Biology, Bone resorption, Bone and Bones, Bone remodeling, 03 medical and health sciences, 0302 clinical medicine, Osteoclast, hemic and lymphatic diseases, medicine, Animals, Syk Kinase, Immunology and Allergy, Bone Resorption, Original Research, SYK (spleen tyrosine kinase), tyrosine kinase, hemic and immune systems, Organ Size, Hematopoietic Stem Cells, Cell biology, enzymes and coenzymes (carbohydrates), Haematopoiesis, in vivo, 030104 developmental biology, medicine.anatomical_structure, osteoclasts, Cre-Lox, biological phenomena, cell phenomena, and immunity, lcsh:RC581-607, Tyrosine kinase, Gene Deletion, 030215 immunology

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bbcbb4bcf10f859bc6960f7c058a1b5Test

المؤلفون: Mingjiang Zhu, Mingming Zhao, Shanshan Zhong, Xinli Xue, Shuyuan Guo, L. L. Li, Jianhong Lu, Yongzhen Tao, Buxing Chen, Qun Chen, Mengqing Xiao, Yujuan Zhuo, Chunzhao Yin, Huiyong Yin, Lemin Zheng, Xia Shen

المصدر: Redox Biology, Vol 21, Iss, Pp-(2019)
Redox Biology

مصطلحات موضوعية: RT, retention time, Male, TLR4, Toll like receptor 4, BEP-CE, Bicyclic endoperoxide and hydroperoxide cholesterol ester, CHD, coronary heart disease, Biochemistry, Mass Spectrometry, Mice, 0302 clinical medicine, LXRα, liver X receptor α, oxLA-CE, oxidized LA-CE, Myocardial infarction, HMGCR, HMG-CoA reductase, CBD, cerebrovascular diseases, lcsh:QH301-705.5, chol-d7, cholesterol-d7, Idol, inducible degrader of the LDL receptor, AMVN, 2, 2′-azobis(2,4-dimethylvaleronitrile), GW, GW 3965, LDLR, LDL receptor, mmLDL, minimally modified LDL, Cholesterol, WT, wide type, Cardiovascular Diseases, Knockout mouse, MI, myocardial infarction, Cholesterol Esters, lcsh:Medicine (General), ch-HpETE, cholesteryl-hydroperoxy-eicosatetraenoate, medicine.medical_specialty, NH4OAc, ammonium acetate, LA-CEOH, LA-CE hydroxide, Lipid peroxidation, CVD, cardiovascular disease, SYK, spleen tyrosine kinase, 03 medical and health sciences, PUFA, polyunsaturated fatty acid, Humans, Aged, TLC, thin layer chromatography, Macrophages, ch-HpODE, cholesteryl-hydroperoxy-octadecadienoate, Lipid Metabolism, medicine.disease, Dil-LDL, 1,1′-dioctadecyl-3,3,3′,3′-tetramethyl-indocarbocyanine perchlorate labeled LDL, 030104 developmental biology, Endocrinology, LA-CE, cholesteryl linoleate, LDL oxidation, Biomarkers, 030217 neurology & neurosurgery, MRM, multiple reaction monitoring, 0301 basic medicine, CE19:0, cholesteryl nonadecanoate, Clinical Biochemistry, ch-HODE, cholesteryl-hydroxy-octadecadienoate, Endogeny, LDL, low density lipoprotein, Pathogenesis, Cholesterol/metabolism, chemistry.chemical_compound, BSTFA+TMCS, Bis-(trimethylsilyl)-trifluoroacetamide+Trimethylchlorosilane, Cholesterol uptake, IS, internal standard, PPh3, triphenylphosphine, CEOH, CE hydroxide, Liver X Receptors, lcsh:R5-920, CEOOH, cholesterol ester hydroperoxide, Chemistry, BMDM, bone marrow-derived macrophage, Middle Aged, CVD, ch-13c,t-HpODE, cholesteryl-13(cis, trans)-hydroperoxy-octadecadienoate, ch-HETE, cholesteryl-hydroxy-eicosatetraenoate, Metabolome, LXR, Female, lipids (amino acids, peptides, and proteins), oxCE, oxidized CE, Research Paper, IPA, isopropanol, AA-CE, cholesteryl arachidonate, Cholesterol ester hydroperoxides, CE, cholesterol ester, T09, T0901317, ROS, reactive oxygen species, Internal medicine, BHT, butylated hydroxytoluene, medicine, Animals, oxLDL, oxidized LDL, Organic Chemistry, IP, intraperitoneal injection, Disease Models, Animal, LDLR, Receptors, LDL, lcsh:Biology (General), NaOMe, sodium methoxide, Lipidomics, LDL receptor, Hepatocytes, Chromatography, Liquid, Lipoprotein

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1989f770bc806092616979f001bbee92Test
http://www.sciencedirect.com/science/article/pii/S2213231718310851Test

المؤلفون: Goggs, Robert, Williams, Christopher M., Mellor, Harry, Poole, Alastair W.

المصدر: Biochemical Journal

مصطلحات موضوعية: rho GTP-Binding Proteins, Syk, spleen tyrosine kinase, Platelet Aggregation, TRIO, triple functional domain containing protein, Review Article, Cdc42, cell division control protein 42, Rac, Ras-related C3 botulinum toxin substrate, ROCK, Rho kinase, MLC, myosin light chain, shape change, Ena, enabled, MTSS1, metastasis suppressor protein 1, FcR, Fc receptor, AP-MS, affinity-purification mass spectrometry, ARP2/3, actin related protein 2/3 complex, Rif, Rho in filopodia (RhoF), WASP, Wiskott–Aldrich syndrome protein, ECM, extracellular matrix, LARG, leukaemia-associated Rho GEF (ARHGEF12), secretion, PI3K, phosphoinositide 3-kinase, PREX-1, PI(3,4,5)P3-dependent Rac exchanger 1 protein, Signal Transduction, VWF, von Willebrand factor, Blood Platelets, PAR, protease activated receptor, NSF, N-ethylmaleimide-sensitive factor, CRP, collagen-related peptide, SNARE, soluble N-ethylmaleimide attachment protein receptors, PF4, platelet factor-4, GEF, guanine nucleotide exchange factor, PLC, phospholipase C, PAK, P21-activated kinase, LAT, linker for activation of T-cells, PKC, protein kinase C, Animals, Humans, cell division control protein 42 (Cdc42), thrombosis, Rho GTPase, Ras homology family GTPase, Rif, ITAM, immunoreceptor tyrosine-based activation motif, Platelet Activation, GDI, guanine nucleotide dissociation inhibitor, RhoG, IMD, IRSp53 and MIM homology domain, ELMO, engulfment and cell motility, VAMP, vesicle-associated membrane protein, F-actin, filamentous actin, TCR, T-cell receptor, GAP, GTPase activating protein, ARHGEF, Rho guanine nucleotide exchange factor, GP, glycoprotein, VASP, vasodilator-stimulated phosphoprotein, DOCK, dedicator of cytokinesis

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=pmid________::8dee12c58f70730a3a55910e7d6987a6Test
http://europepmc.org/articles/PMC4357237Test

المؤلفون: Palash Chandra Maity, Michael Reth, Kathrin Klaesener, Jianying Yang

المصدر: Biochimica et Biophysica Acta

مصطلحات موضوعية: Nanocluster, Syk, spleen tyrosine kinase, Cell, Receptors, Cell Surface, Biology, Article, PALM, photoactivated localization microscopy, Cell membrane, dSTORM, direct stochastic optical reconstruction microscopy, Cell Compartmentation, medicine, Animals, Humans, TEM, transmission electron microscopy, Molecular Biology, B cell antigen receptor, Protein islands, B-Lymphocytes, PLA, proximity ligation assay, BN-PAGE, blue native polyacrylamide gel electrophoresis, Cell Membrane, breakpoint cluster region, Models, Immunological, Biological membrane, Cell Biology, BCR, B cell antigen receptor, Cell biology, medicine.anatomical_structure, Membrane, Membrane protein, PM, plasma membrane, Nanoparticles, Fluid mosaic model, TM, transmembrane

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::436c2176277ef379c869f11a5ff32c87Test
http://europepmc.org/articles/PMC4547082Test