المؤلفون: Signe Bollerup, Frederik Engsig, Sofie Hallager, Amanda Mocroft, Birgit T Roege, Peer B Christensen, Alex L Laursen, Henrik Krarup, Mette R Clausen, Peter Thielsen, Lone G Madsen, Lars Noerregaard, Toke S Barfod, Ulla Balslev, Britta Tarp, Jesper B Hansen, Lone H Mygind, Jan Gerstoft, Nina Weis

المصدر: Bollerup, S, Engsig, F, Hallager, S, Mocroft, A, Roege, B T, Christensen, P B, Laursen, A L, Krarup, H, Clausen, M R, Thielsen, P, Madsen, L G, Noerregaard, L, Barfod, T S, Balslev, U, Tarp, B, Hansen, J B, Mygind, L H, Gerstoft, J & Weis, N 2022, ' Incidence of Hepatocellular Carcinoma and Decompensated Liver Cirrhosis and Prognostic Accuracy of the PAGE-B HCC Risk Score in a Low Endemic Hepatitis B Virus Infected Population ', Journal of Hepatocellular Carcinoma, vol. 9, pp. 1093-1104 . https://doi.org/10.2147/JHC.S372571Test

مصطلحات موضوعية: ANTIVIRAL TREATMENT, OUTCOMES, SERUM ALANINE AMINOTRANSFERASE, viral hepatitis, morbidity, PROGRESSION, HBEAG, DISEASE, PREDICTS, UPPER LIMITS, MANAGEMENT, Scandinavia, CAUCASIANS, hepatitis B virus, nationwide, Journal of Hepatocellular Carcinoma

وصف الملف: text/html; application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a297bc42293ee29a254b2432bd5b40f8Test
https://pubmed.ncbi.nlm.nih.gov/36281336Test

المؤلفون: Yueyong Zhu, Meng-Xin Lin, Yu-Rui Liu, Na-Ling Kang, Zu-Xiong Huang, Jie-Min Zhang, Da-Wu Zeng, Xu-Dong Chen

المصدر: World Journal of Gastroenterology

مصطلحات موضوعية: Adult, Liver Cirrhosis, Male, Hepatitis B virus, HBsAg, medicine.medical_specialty, Cirrhosis, Liver fibrosis, medicine.disease_cause, Gastroenterology, 03 medical and health sciences, Serum ceruloplasmin, Hepatitis B, Chronic, 0302 clinical medicine, Retrospective Study, Internal medicine, medicine, Humans, Platelet, Retrospective Studies, Receiver operating characteristic, biology, business.industry, Noninvasive model, Ceruloplasmin, Alanine Transaminase, General Medicine, Middle Aged, medicine.disease, Receiver-operating characteristic, Chronic hepatitis B infection, Serum alanine aminotransferase, Liver, ROC Curve, 030220 oncology & carcinogenesis, biology.protein, Female, 030211 gastroenterology & hepatology, business, Biomarkers

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::728d957a3db7b1fbd97fc3676d8d1b75Test
https://doi.org/10.3748/wjg.v26.i27.3952Test

المؤلفون: Yajie Wen, Jiahong Sun, Panpan Chen, Wenzhou Li, Tingying Jiao, Huichang Bi, Yanying Zhou, Yixin Chen, Lihuan Guan, Pan Chen, Fan Xiaomei, Yiming Jiang, Min Huang

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 1, Pp 89-99 (2021)

مصطلحات موضوعية: GSTα, glutathianone S-transferase α, NAPQI, N-acetyl p-benzoquinone imine, AST, aspartate aminotransferase, Pharmacology, medicine.disease_cause, BrdU, bromodeoxyuridine, CDK4, cyclin-dependent kinase 4, 0302 clinical medicine, AAV, adeno-associated virus, ECL, electrochemiluminescence, GSTμ, glutathione S-transferase μ, GSH, glutathione, General Pharmacology, Toxicology and Pharmaceutics, HO-1, heme oxygenase-1, Liver injury, 0303 health sciences, Gene knockdown, biology, LDH, lactate dehydrogenase, Chemistry, CYP450, cytochromes P450, digestive, oral, and skin physiology, SIRT6, sirtuin 6, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Hepatocyte, Sirtuin, NRF2, nuclear factor erythroid 2-related factor 2, KEAP1, Kelch-like ECH-associated protein 1, Original Article, SIRT6, DNA damage, APAP, acetaminophen, ARE, antioxidant response element, NRF2, ALT, serum alanine aminotransferase, 03 medical and health sciences, H3K9ac, histone H3 Nε-acetyl-lysines 9, CCK-8, cell counting kit-8, ROS, reactive oxygen species, ALF, acute liver failure, Dox, doxorubicin, H3K56ac, histone H3 Nε-acetyl-lysines 56, medicine, Viability assay, 030304 developmental biology, Acetaminophen, P53, CCND1, cyclin D1, lcsh:RM1-950, Hepatotoxicity, medicine.disease, BCA, bicinchoninic acid, lcsh:Therapeutics. Pharmacology, DCF, dichlorofluorescein, siRNA, small interfering RNA, biology.protein, H&E, hematoxylin and eosin, CCNA1, cyclin A1, NQO1, NAD(P)H quinone dehydrogenase 1, Co-IP, co-immunoprecipitation, Oxidative stress

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73bdb116a375dde7c9f1a71079b6d0f0Test
http://europepmc.org/articles/PMC7838028Test

المؤلفون: Shira Zelber-Sagi, Rebecca Dorner, Giulio Marchesini, Marko Korenjak, Christos Lionis, Jeffrey V. Lazarus, Sven Francque, Achim Kautz, Luca Busetto, José Willemse, G. Koek, Dror Dicker, Kate Hallsworth, Shlomo Vinker, Gema Frühbeck, Euan Woodward, Mehmet Ungan, Juan M. Mendive, Martine Walmsley

المساهمون: Francque, Sven M, Marchesini, Giulio, Kautz, Achim, Walmsley, Martine, Dorner, Rebecca, Lazarus, Jeffrey V, Zelber-Sagi, Shira, Hallsworth, Kate, Busetto, Luca, Frühbeck, Gema, Dicker, Dror, Woodward, Euan, Korenjak, Marko, Willemse, José, Koek, Gerardus H, Vinker, Shlomo, Ungan, Mehmet, Mendive, Juan M, Lionis, Christos, Interne Geneeskunde, MUMC+: MA Maag Darm Lever (9), RS: NUTRIM - R2 - Liver and digestive health

المصدر: JHEP Reports
JHEP Reports, Vol 3, Iss 5, Pp 100322-(2021)
JHEP Reports, 3(5):100322. Elsevier BV

مصطلحات موضوعية: NASH, non-alcoholic steatohepatiti, Y GASTRIC BYPASS, Disease, RC799-869, PLACEBO-CONTROLLED TRIAL, LIFE-STYLE MODIFICATION, cardiovascular disease, LDL, low-density lipoprotein, HEPATOCELLULAR-CARCINOMA, non-invasive test, T2D, GLP-1 RAs, glucagon-like receptor 1 agonists, European Association for the Study of Obesity, HCC, Gastroenterology, NASH, specific, Diseases of the digestive system. Gastroenterology, CAP, controlled attenuation parameter, CT, computed tomography, FXR, ASH, alcoholic steatohepatitis, GP, non-alcoholic steatohepatitis, GLP-1 RAs, glucagon-like receptor 1 agonist, LDL, low-density lipoproteins, medicine.medical_specialty, HDL, achievable, NASH, non-alcoholic steatohepatitis, T2D, type 2 diabetes, high-density lipoprotein, CVD, cardiovascular disease, LDL, Patient Guideline, Quality of life (healthcare), FXR, farnesoid X receptor, NAFLD, low-density lipoproteins, GP, general practitioner, NAFL, non-alcoholic fatty liver, FIB-4, fibrosis-4 index, Intensive care medicine, computed tomography, Guideline, medicine.disease, T1D, type 1 diabete, digestive system diseases, NIT, Human medicine, farnesoid X receptor, type 1 diabetes, BMI, body mass index, EASL, European Association for the Study of the Liver, Placebo-controlled study, Chronic liver disease, GLP-1 RAs, QUALITY-OF-LIFE, alcoholic steatohepatitis, European Association for the Study of Diabetes, EASD, European Association for the Study of Diabetes, Immunology and Allergy, magnetic resonance imaging, NASH Clinical Research Network, ALD, alcohol-related or alcoholic liver disease, Disease management (health), glucagon-like receptor 1 agonists, EASO, European Association for the Study of Obesity, NASH CRN, NASH Clinical Research Network, ASH, alcoholic steatohepatiti, Fatty liver, timely, hepatocellular carcinoma, CVD, magnetic resonance elastography, MRE, NAFL, FIB-4, non-alcoholic fatty liver, type 2 diabetes, T1D, type 1 diabetes, CAP, controlled attenuation parameter, CT, European Association for the Study of the Liver, MRI, fibrosis-4 index, NAFLD, non-alcoholic fatty liver disease, EASD, HDL, high-density lipoprotein, UNITED-STATES, ASH, body mass index, EASL, measurable, BMI, NIT, non-invasive test, Internal Medicine, medicine, NASH CRN, HEPATIC STEATOSIS, HCC, hepatocellular carcinoma, MRE, magnetic resonance elastography, MRI, magnetic resonance imaging, SMART, specific, measurable, achievable, relevant, timely, Disease burden, BARIATRIC SURGERY, Hepatology, SMART, business.industry, SERUM ALANINE AMINOTRANSFERASE, non-alcoholic fatty liver disease, PHYSICAL-ACTIVITY, alcohol-related or alcoholic liver disease, EASD, European Association for the Study of Diabete, EASO, ALD, general practitioner, relevant, T1D, business

وصف الملف: ELETTRONICO

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc5e84bfe19b52d5e0324b299615b0e1Test
https://pubmed.ncbi.nlm.nih.gov/34693236Test

المؤلفون: Hajime Moteki, Mitsutoshi Kimura, Masahiko Ogihara, Kazuki Kurihara, Hideshi Natsume

المصدر: Biologicalpharmaceutical bulletin. 43(11)

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, Male, medicine.medical_specialty, medicine.medical_treatment, Pharmaceutical Science, Receptor, IGF Type 1, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, medicine, Extracellular, partial hepatectomy (PHx), Animals, Hepatectomy, serum alanine aminotransferase (ALT), Cysteine, RNA, Messenger, Insulin-Like Growth Factor I, Phosphorylation, Rats, Wistar, Receptor, Protein kinase B, Cell Proliferation, Pharmacology, Mitogen-Activated Protein Kinase 1, Kinase, Chemistry, Growth factor, digestive, oral, and skin physiology, insulin-like growth factor (IGF)-1, General Medicine, Liver regeneration, Liver Regeneration, Rats, S-allylcysteine (SAC), 030104 developmental biology, Endocrinology, Liver, 030220 oncology & carcinogenesis, Models, Animal, Liver function, Proto-Oncogene Proteins c-akt

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9af25575c76bd7e9c26d19ade224c0b9Test
https://pubmed.ncbi.nlm.nih.gov/33132323Test

المؤلفون: L. Venkatakrishnan, Anil Mathew, Noel George, Siddharth Dharamsi, Alan Jose

المصدر: Advanced Biomedical Research

مصطلحات موضوعية: medicine.medical_specialty, Creatinine, biology, Receiver operating characteristic, business.industry, serum alanine aminotransferase, Liver cell, digestive, oral, and skin physiology, Serum albumin, Liver failure, Curve analysis, General Medicine, Gastroenterology, chemistry.chemical_compound, prognostic survival factors, chemistry, Internal medicine, medicine, biology.protein, In patient, Original Article, business, Acute liver failure, Hepatitis E virus infection

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adce449642b1689b99c21acb296c525aTest
http://europepmc.org/articles/PMC7532818Test

المؤلفون: Mazin A. Zamazami, Amani Mohammed Al-Hamed, Haddad A. El Rabey, Madeha N. Al-Seeni

المصدر: Toxicology Reports, Vol 5, Iss, Pp 146-155 (2018)
Toxicology Reports

مصطلحات موضوعية: Health, Toxicology and Mutagenesis, 010501 environmental sciences, Pharmacology, Kidney, Toxicology, G3, the third group (G3) received 10 mg/kg b.w. tartrazine and 3.75 mg/kg b.w. sulfanilic acid and cotreated with 10 ml/kg body weight Nigella sativa oil for 8 weeks, 01 natural sciences, LDL, low density lipoprotein, Lipid peroxidation, chemistry.chemical_compound, 0302 clinical medicine, AST, serum aspartate aminotransferase, Nigella sativa, G2, the second positive control group fed diets containing 10 mg/kg b.w. tartrazine and 3.75 mg/kg b.w. sulfanilic acid, Tartrazine, TG, triglyceride, Stomach, food and beverages, B.W., body weight, Honey, Food additives, medicine.anatomical_structure, Liver, 030220 oncology & carcinogenesis, Toxicity, G1, the first negative control untreated group fed basal diet containing 3.75 mg/kg b.w. sulfanilic acid, BWG, body weight gain, Renal function, FER, food efficiency ratio, Article, ALT, serum alanine aminotransferase, 03 medical and health sciences, lcsh:RA1190-1270, medicine, Adverse effect, ComputingMethodologies_COMPUTERGRAPHICS, 0105 earth and related environmental sciences, lcsh:Toxicology. Poisons, MDA, malondialdehyde, VLDL, very low density lipoproteins, business.industry, TC, total cholesterol, chemistry, ALP, serum alkaline phosphatase, Rat, business, N.N cellulose, non-nutritive cellulose

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5634eadd32501d010da195dbeb2c4fdaTest
http://www.sciencedirect.com/science/article/pii/S2214750017301373Test

المؤلفون: Misbah Munir, Dr Yousaf Jamil, Dr. Naila Alam

مصطلحات موضوعية: Hepatitis C Virus (HCV), Ribavirin & Interferon Therapy (R&IT), Serum Alanine Aminotransferase Levels (SAAL), Chronic Hepatitis C (CHC)

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83dc3003fef30b0ec9f281fcfde59cf5Test

المؤلفون: LI Bing

المصدر: Linchuang Gandanbing Zazhi, Vol 30, Iss 5, Pp 413-416 (2014)

مصطلحات موضوعية: ObjectiveTo analyze the clinical features and laboratory test results of patients with autoimmune hepatitis (AIH)-primary biliary cirrhosis (PBC) overlap syndrome, laboratory test results, the correct diagnosis rate was the lowest (52.83%), and multiple comparisons were made by SNK-q test, comparison of qualitative data between groups was made using R×C contingency table, and it took the longest time (8±7.7 d) to confirm the diagnosis on admission. ConclusionThe clinical manifestations of patients with AIH-PBC overlap syndrome are more similar to those of PBC patients, but their biochemical test results are more similar to those of AIH patients. AIH-PBC overlap syndrome has the clinical features of both AIH and PBC, digestive system diseases, as well as their correct diagnosis rate and time to diagnosis. MethodsFifty-three patients who were diagnosed by liver biopsy as having AIH-PBC overlap syndrome from January 2009 to June 2013 were selected as subjects, 53 AIH patients and 53 PBC patients were selected as control groups. Their clinical manifestations, 27 were positive for anti-mitochondrial antibody-M2, a serum total bilirubin level of 38.07±6.82 μmol/L, and a serum gamma-glutamyl transpeptidase level of 57.57±78.84 U/L. ALP showed significant difference between the patients with AIH-PBC overlap syndrome and control groups. The serum level of immunoglobulin M in overlap syndrome patients was 3.33±2.12 g/L, which was significantly different from those of two control groups. Of the 53 overlap syndrome patients, and the positive rate was significantly different from those of two control groups. Without liver biopsy, and diagnosis on admission were retrospectively analyzed. Comparison of normally distributed quantitative data between groups was made by one-way analysis of variance, lcsh:Diseases of the digestive system. Gastroenterology, lcsh:RC799-869, and multiple comparisons were made by Scheffe′s confidence interval test. ResultsThe 53 patients with AIH-PBC overlap syndrome had a serum alanine aminotransferase level of 173.65±52.08 U/L, a serum alkaline phosphatase (ALP) level of 293.81±28.89 U/L

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doajarticles::66e86057c5f106dfde33d7799ebcd51aTest
http://www.lcgdbzz.org/qk_content.asp?id=5847&ClassID=42414435Test

المؤلفون: Shuang Chen, Guozhe Sun, Zhao Li, Shasha Yu, Yingxian Sun, Hongmei Yang, Xiaofan Guo

المصدر: International Journal of Environmental Research and Public Health, Vol 13, Iss 9, p 841 (2016)
International Journal of Environmental Research and Public Health; Volume 13; Issue 9; Pages: 841
International Journal of Environmental Research and Public Health

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, medicine.medical_specialty, China, serum uric acid, serum alanine aminotransferase, Health, Toxicology and Mutagenesis, Population, lcsh:Medicine, Reference range, hyperuricemia, Biology, Gastroenterology, Article, 03 medical and health sciences, 0302 clinical medicine, Asian People, Reference Values, Internal medicine, alanine aminotransferase (ALT), medicine, Odds Ratio, Prevalence, Humans, Hyperuricemia, education, Metabolic Syndrome, education.field_of_study, Alanine, Confounding, lcsh:R, Public Health, Environmental and Occupational Health, Alanine Transaminase, Odds ratio, Middle Aged, medicine.disease, Confidence interval, Uric Acid, 030104 developmental biology, Endocrinology, Cross-Sectional Studies, Logistic Models, Quartile, 030211 gastroenterology & hepatology, Female, Metabolic syndrome

وصف الملف: application/pdf

الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::696d8e412287efd8f2ecead17feb68aaTest
http://www.mdpi.com/1660-4601/13/9/841Test