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1
المؤلفون: James Yarmolinsky, Virginia Díez-Obrero, Tom G Richardson, Marie Pigeyre, Jennifer Sjaarda, Guillaume Paré, Venexia M Walker, Emma E Vincent, Vanessa Y Tan, Mireia Obón-Santacana, Demetrius Albanes, Jochen Hampe, Andrea Gsur, Heather Hampel, Rish K Pai, Mark Jenkins, Steven Gallinger, Graham Casey, Wei Zheng, Christopher I Amos, International Lung Cancer Consortium, PRACTICAL consortium, MEGASTROKE consortium, George Davey Smith, Richard M Martin, Victor Moreno
المصدر: PLoS Medicine, Vol 19, Iss 2, p e1003897 (2022)
Yarmolinsky, J, Díez-Obrero, V, Richardson, T G, Pigeyre, M, Sjaarda, J, Paré, G, Walker, V M, Vincent, E E, Tan, V Y, Obón-Santacana, M, Albanes, D, Hampe, J, Gsur, A, Hampel, H, Pai, R K, Jenkins, M, Gallinger, S, Casey, G, Zheng, W, Amos, C I, International Lung Cancer Consortium, The PRACTICAL Consortium, The MEGASTROKE consortium, Smith, G D, Martin, R M & Moreno, V 2022, ' Genetically proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers : A mendelian randomization analysis ', PLOS Medicine, vol. 19, no. 2, e1003897 . https://doi.org/10.1371/journal.pmed.1003897Test
the PRACTICAL Consortium 2022, ' Genetically proxied therapeutic inhibition of antihypertensive drug targets and risk of common cancers : A mendelian randomization analysis ', PLoS Medicine, vol. 19, no. 2, e1003897 . https://doi.org/10.1371/journal.pmed.1003897Test
Dipòsit Digital de la UB
Universidad de Barcelonaمصطلحات موضوعية: Male, Polymorphism, Single Nucleotide/drug effects, Antihypertensive Agents/adverse effects, Mendelian Randomization Analysis/methods, Peptidyl-Dipeptidase A/genetics, General Medicine, Receptors, Adrenergic, beta-1/genetics, Blood Pressure/drug effects, Risk Factors, Neoplasms/chemically induced, Hypertension, Genome-Wide Association Study/methods, Humans, Medicine, Female, Hipertensió, ICEP, Solute Carrier Family 12, Member 3/genetics, Càncer, Cancer
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58ebdcff10cb8f88caaecd212f39594eTest
https://doaj.org/article/34b1a0c7008a49a584262cd8aef7a5ecTest -
2
المؤلفون: Alex K. Shalek, Kun Zhang, Christopher W. Peterson, Orit Rosen, Alison Yu, Robert Lafyatis, Samuel W. Kazer, Oliver Eickelberg, Sarah A. Teichmann, Mauricio Rojas, Martijn C. Nawijn, Colin D. Bingle, Thu Elizabeth Duong, Manuel Garber, Magali Plaisant, Philana Ling Lin, Christine S. Falk, Jennifer P. Wang, Xin Sun, Hengqi Betty Zheng, G. James Gatter, Sarah K. Nyquist, Malte Kühnemund, Joachim L. Schultze, Mark A. Krasnow, Maarten van den Berge, Yan Xu, Samuel J. Allon, Daniel F. Dwyer, Peter Horvath, Benjamin Doran, Brian M. Lin, Herbert B. Schiller, Blake M. Hauser, Fabian J. Theis, Avrum Spira, Paul A. Reyfman, Hans-Peter Kiem, Shaina L. Carroll, Zhiru Guo, Douglas P. Shepherd, Michael von Papen, Ian M. Mbano, Michael Farzan, Daniel Lingwood, JoAnne L. Flynn, Christoph Muus, Dana Pe'er, Stephen R. Quake, Travis K. Hughes, Sarah M. Fortune, Sten Linnarson, Chase J. Taylor, Tanya M. Laidlaw, Emma L. Rawlins, Bonnie Berger, Ashraf S. Yousif, Joakim Lundeberg, Jeffrey A. Whitsett, Ian A. Glass, Delphine Gras, Max A. Seibold, Jay Rajagopal, Jared Feldman, Victor Tkachev, Benjamin E. Mead, Joseph E. Powell, Aviv Regev, Alasdair Leslie, Robert W. Finberg, Yuming Cao, Jennifer M.S. Sucre, Marko Vukovic, Scott B. Snapper, Vincent N. Miao, Naftali Kaminski, Laure-Emmanuelle Zaragosi, Caylin G. Winchell, Faith Taliaferro, Marko Nikolic, Ilias Angelidis, Leslie S. Kean, Lucrezia Colonna, Kathleen M. Buchheit, Aaron G. Schmidt, Ramnik J. Xavier, Tushar J. Desai, Marc H. Wadsworth, Joshua A. Boyce, Alexander M. Tsankov, Nora A. Barrett, Pascal Barbry, Muzlifah Haniffa, Heiko Adler, Alvis Brazma, Hannah P. Gideon, Meshal Ansari, Jason R. Spence, Avinash Waghray, Constantine N. Tzouanas, Jose Ordovas-Montanes, Jonathan A. Kropski, Nicholas E. Banovich, Purushothama Rao Tata, Kerstin B. Meyer, Christos Samakovlis, Haeock Lee, Carly G. K. Ziegler, Alexander V. Misharin, Deborah T. Hung, Sylvie Leroy, Julia Bals, Vanessa Mitsialis, Kourosh Saeb-Parsy
المساهمون: Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research (C2VN), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Centre National de la Recherche Scientifique (CNRS), FRM (DEQ20180339158), National Infrastructure France Génomique (Commissariat aux Grands Investissements, ANR-10-INBS-09-03, ANR-10-INBS-09-02), ANR-19-P3IA-0002,3IA@cote d'azur,3IA Côte d'Azur(2019), European Project: 874656,discovAIR, Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory, Koch Institute for Integrative Cancer Research at MIT, Groningen Research Institute for Asthma and COPD (GRIAC)
المصدر: Cell
Cell, 2020, 181 (5), pp.1016-1035.e19. ⟨10.1016/j.cell.2020.04.035⟩
Cell, Elsevier, 2020, 181 (5), pp.1016-1035.e19. ⟨10.1016/j.cell.2020.04.035⟩
Cell 181, 1016-1035 (2020)
Elsevier
Cell, 181(5), 1016-1035.e19. CELL PRESSمصطلحات موضوعية: Interferon Type I/immunology, Pneumonia, Viral/virology, Viral/virology, [SDV]Life Sciences [q-bio], ACE2, HIV Infections, non-human primate, HIV Infections/immunology, Mice, 0302 clinical medicine, Single-cell analysis, Alveolar Epithelial Cells/immunology, Interferon, Influenza, Human/immunology, Receptors, Child, Lung, Cells, Cultured, Virus/genetics, 0303 health sciences, Cultured, Serine Endopeptidases, Human/immunology, interferon, Nasal Mucosa/cytology, respiratory system, 3. Good health, Cell biology, Up-Regulation, Interferon Type I, Receptors, Virus, Angiotensin-Converting Enzyme 2, Goblet Cells, Enterocytes/immunology, Single-Cell Analysis, Coronavirus Infections, hormones, hormone substitutes, and hormone antagonists, medicine.drug, Proteases, Coronavirus Infections/virology, Adolescent, Cells, Pneumonia, Viral, Receptors, Virus/genetics, Peptidyl-Dipeptidase A/genetics, Lung injury, Biology, Peptidyl-Dipeptidase A, TMPRSS2, General Biochemistry, Genetics and Molecular Biology, Article, Cell Line, ISG, 03 medical and health sciences, Betacoronavirus, Serine Endopeptidases/metabolism, Downregulation and upregulation, Lung/cytology, Influenza, Human, scRNA-seq, medicine, Ace2, Covid-19, Isg, Sars-cov-2, Human, Influenza, Mouse, Non-human Primate, Scrna-seq, Tuberculosis, Animals, Humans, human, Pandemics, Tuberculosis/immunology, mouse, 030304 developmental biology, Innate immune system, SARS-CoV-2, Betacoronavirus/physiology, Interferon-stimulated gene, COVID-19, Mycobacterium tuberculosis, Pneumonia, Macaca mulatta, respiratory tract diseases, Nasal Mucosa, Enterocytes, Goblet Cells/immunology, Alveolar Epithelial Cells, 030217 neurology & neurosurgery
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::727543612f7db162539d6c42ca832836Test
https://doi.org/10.1016/j.cell.2020.04.035Test -
3
المؤلفون: Christophe Jean-Yves Decrind, Yves Donati, Georges E. Grau, Denis R. Morel, Philippe Morel, Bara Ricou, Anastase Spiliopoulos, Nabil Mili, Sylvie Kossodo, Jinning Lou, Peter M. Suter
المصدر: In vitro cellular & developmental biology. Animal, Vol. 34, No 7 (1998) pp. 529-36
مصطلحات موضوعية: CD31, Antigens, CD31/metabolism, Pathology, medicine.medical_specialty, Lung/blood supply, Endothelium, RNA, Messenger/genetics/metabolism, Cytological Techniques, Peptidyl-Dipeptidase A/genetics, Peptidyl-Dipeptidase A, ddc:616.07, Tumor Necrosis Factor-alpha/physiology, Lipoproteins, LDL/metabolism, Von Willebrand factor, Von Willebrand Factor/metabolism, von Willebrand Factor, E-Selectin/metabolism, Respiratory Distress Syndrome, Adult/pathology, medicine, Humans, RNA, Messenger, Lung, DNA Primers, Respiratory Distress Syndrome, ddc:617, Base Sequence, biology, Tumor Necrosis Factor-alpha, Contact inhibition, Cytological Techniques/standards, Cell Biology, General Medicine, Lipoproteins, LDL, Platelet Endothelial Cell Adhesion Molecule-1, medicine.anatomical_structure, Cell culture, Immunology, biology.protein, cardiovascular system, Tumor necrosis factor alpha, Endothelium, Vascular, Endothelium, Vascular/cytology/metabolism/pathology, Stem cell, E-Selectin, Developmental Biology
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c9d5e55cd0a29f78ee1e6daa4fc513cTest
http://doc.rero.ch/record/314647/files/11626_1998_Article_112.pdfTest -
4
المؤلفون: Catalina Santiago, Félix Gómez-Gallego, Marta Gonzalez-Freire, Carlos A. Muniesa, Alejandro Lucia, M. Fernández del Valle, Carl Foster, Margarita Pérez
المصدر: International Journal of Sports Medicine. 30:66-72
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Genotype, Peptidyl-Dipeptidase A/*Genetics, Ace genotype, Peak power output, Physical Therapy, Sports Therapy and Rehabilitation, Peptidyl-Dipeptidase A, Biology, Fisiología humana, Respiratory compensation, Physical Endurance/*Genetics, Pulmonary Ventilation/Physiology, Atleta, Internal medicine, medicine, Humans, Actinin, Orthopedics and Sports Medicine, Gross efficiency, Gene, Analysis of Variance, Bicycling, Deporte, Respiratory Function Tests, Phenotype, Endocrinology, Physical Endurance, Exercise Test, Physical therapy, Analysis of variance, Pulmonary Ventilation, human activities
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ce293dfc17acd560fff18570bee4e91Test
https://doi.org/10.1055/s-2008-1038677Test -
5
المؤلفون: Ceren Acar, Harun Evrengul, Deniz Seleci, Asuman Kaftan, Seyhan Tanriverdi, Halil Tanriverdi, Omur Kuru, Hatice Mergen
المصدر: Heart and Vessels. 22:1-8
مصطلحات موضوعية: Carotid Artery Diseases, Male, angiocardiography, AT1R A/C1166 polymorphism, Adult, Aged, Alleles, Carotid Artery Diseases/*genetics/*physiopathology, Coronary Angiography, Coronary Vessels/*physiopathology, Female, Humans, Middle Aged, Peptidyl-Dipeptidase A/*genetics, Polymorphism, Genetic/*physiology, Regional Blood Flow, Renin-Angiotensin System, Tunica Intima/pathology, Tunica Media/pathology, Intima-media thickness, correlation analysis, genotype, Renin-angiotensin gene system, image display, Coronary artery disease, cardiovascular disease, Carotid atherosclerosis, coronary artery blood flow, renin angiotensin aldosterone system, Myocardial infarction, Common carotid artery, statistical significance, clinical article, biology, adult, pathogenesis, artery intima, allele, article, vascular disease, Coronary Vessels, transducer, ACEI/D polymorphism, aged, female, medicine.anatomical_structure, priority journal, risk factor, Cardiology, Tunica Media, Cardiology and Cardiovascular Medicine, coronary artery disease, gene insertion, TIMI, medicine.medical_specialty, regulatory mechanism, angiotensin 1 receptor, dipeptidyl carboxypeptidase, common carotid artery, Peptidyl-Dipeptidase A, artery media, Internal medicine, medicine.artery, medicine, inheritance, controlled study, human, cardiovascular diseases, artery wall, Polymorphism, Genetic, Slow coronary flow, carotid artery, gene deletion, business.industry, disease association, echography, Angiotensin-converting enzyme, medicine.disease, Angiotensin II, thickness, Coronary arteries, enzyme polymorphism, biology.protein, Gene polymorphism, atherosclerosis, Tunica Intima, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7d718dcd247dbc8ffed8d0c8678ed4eTest
https://doi.org/10.1007/s00380-006-0925-1Test -
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المؤلفون: Ceylan Ayada, Ümran Toru, Sebahat Turgut, Osman Genç, Günfer Turgut, Server Sahin, A. Yerlikaya
مصطلحات موضوعية: Gene Frequency, Genetic Association Studies, Genetic Predisposition to Disease, Humans, INDEL Mutation/*genetics, Peptidyl-Dipeptidase A/*genetics, Pulmonary Disease, Chronic Obstructive/*genetics/pathology, Renin-Angiotensin System/*genetics, Risk Factors, Turkey, genomic DNA, genetic association, genotype, polymerase chain reaction, genetic risk, Gastroenterology, Turkey (republic), Turkish population, Renin-Angiotensin System, Pulmonary Disease, Chronic Obstructive, INDEL Mutation, renin angiotensin aldosterone system, Genotype, genetic variability, genetic polymorphism, genetics, pathophysiology, COPD, education.field_of_study, clinical article, biology, Chronic obstructive pulmonary disease, allele, General Medicine, risk factor, Renin angiotensin system, blood sampling, Angiotensin converting enzyme, medicine.medical_specialty, Population, dipeptidyl carboxypeptidase, DNA determination, Peptidyl-Dipeptidase A, Article, Internal medicine, geographic distribution, medicine, Genetic predisposition, ACE protein, human, heterozygosity, controlled study, human, education, Molecular Biology, Allele frequency, gene identification, business.industry, population genetics, Angiotensin-converting enzyme, ACE gene, medicine.disease, DNA isolation, Endocrinology, gene function, biology.protein, gene expression, Turk (people), pathology, homozygosity, business, genetic predisposition, chronic obstructive lung disease, Blood sampling
وصف الملف: application/pdf
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f6d6032137ce50699698c4d9415dcd5Test
https://hdl.handle.net/20.500.12438/4548Test -
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المؤلفون: Ioanna Bouba, Athina Tatsioni, Charilaos Kostoulas, Ioannis Georgiou, Sotirios Maranis, Sotirios Giannopoulos, Athanassios P. Kyritsis, Sofia Markoula
المصدر: Journal of the Renin-Angiotensin-Aldosterone System, Vol 12 (2011)
مصطلحات موضوعية: Male, medicine.medical_specialty, Medicine (General), Stroke/complications/*enzymology/*genetics, Myocardial Ischemia, Peptidyl-Dipeptidase A, Peptidyl-Dipeptidase A/*genetics, Endocrinology, R5-920, Gene Frequency, Polymorphism (computer science), Internal medicine, Ischaemic stroke, Genotype, Internal Medicine, medicine, Humans, Medical history, Genetic Predisposition to Disease, Allele, Gene, Stroke, Myocardial Ischemia/*complications/*enzymology/genetics, Sex Characteristics, biology, business.industry, Hypertension/complications/enzymology/genetics, Angiotensin-converting enzyme, Middle Aged, medicine.disease, Atherosclerosis, Atherosclerosis/complications/enzymology/genetics, Gene Frequency/genetics, Case-Control Studies, Hypertension, biology.protein, Female, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80823a56726a80349926c0dc85832263Test
https://pubmed.ncbi.nlm.nih.gov/21421656Test -
8
المؤلفون: Gang Xu, Dong Li, Tong Liu, Michael Shehata, Panagiotis Korantzopoulos, Xunzhang Wang, Guangping Li
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Peptidyl-Dipeptidase A, Bioinformatics, Peptidyl-Dipeptidase A/*genetics, Renin-Angiotensin System, INDEL Mutation, Risk Factors, Physiology (medical), Internal medicine, Atrial Fibrillation, Medicine, Insertion deletion, Humans, Polymorphism, Genetic/genetics, Aged, Polymorphism, Genetic, biology, business.industry, Case-control study, Angiotensin-converting enzyme, Atrial fibrillation, Atrial Fibrillation/epidemiology/*genetics/physiopathology, Middle Aged, medicine.disease, Clinical trial, INDEL Mutation/*genetics, Endocrinology, Meta-analysis, Case-Control Studies, biology.protein, Dominant model, Female, Gene polymorphism, Renin-Angiotensin System/physiology, Cardiology and Cardiovascular Medicine, business
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cb34bb3b79e1ba9ba3bf6720e1ebaffTest
http://olympias.lib.uoi.gr/jspui/handle/123456789/23675Test -
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المؤلفون: Raziye Akcılar, Ceylan Ayada, Sebahat Turgut, Fulya Akin, Günfer Turgut
مصطلحات موضوعية: Male, systolic blood pressure, genetic association, genotype, Angiotensinogen, cholesterol blood level, Blood Pressure, insulin blood level, low density lipoprotein cholesterol, chemistry.chemical_compound, Gene Frequency, INDEL Mutation, high density lipoprotein cholesterol, insulin resistance, Genotype, genetic polymorphism, Receptor, clinical article, biology, adult, article, General Medicine, Middle Aged, growth hormone blood level, female, Female, triacylglycerol, Acromegaly/enzymology/*genetics/physiopathology, Adult, Angiotensinogen/*genetics, Blood Pressure/genetics, Case-Control Studies, Gene Frequency/genetics, Genetic Predisposition to Disease, Humans, INDEL Mutation/*genetics, Peptidyl-Dipeptidase A/*genetics, Polymorphism, Single Nucleotide/*genetics, Receptor, Angiotensin, Type 1/*genetics, Angiotensin converting enzyme, medicine.medical_specialty, insulin, hypertension, angiotensin 1 receptor, dipeptidyl carboxypeptidase, AT1-receptor, Peptidyl-Dipeptidase A, gene frequency, Polymorphism, Single Nucleotide, Receptor, Angiotensin, Type 1, protein denaturation, male, Internal medicine, Acromegaly, Genetics, medicine, controlled study, human, Polymorphism, Molecular Biology, Angiotensin II receptor type 1, Triglyceride, diastolic blood pressure, Angiotensin-converting enzyme, medicine.disease, triacylglycerol blood level, Angiotensin II, somatomedin C, body mass, Endocrinology, Blood pressure, glucose blood level, chemistry, biology.protein, homozygosity
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2e76bb23295505227da5da7e4e11c32Test
http://acikerisim.pau.edu.tr:8080/xmlui/handle/11499/6129Test -
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المؤلفون: Markoula, S., Giannopoulos, S., Asproudis, I., Kostoulas, C., Nikas, A., Bagli, E., Kyritsis, A. P., Ioannis Georgiou
المصدر: Scopus-Elsevier
مصطلحات موضوعية: Aged, 80 and over, Male, Threonine, Alanine, Polymorphism, Genetic, Genotype, Receptor, Angiotensin, Type 1/*genetics, Age Factors, Middle Aged, Peptidyl-Dipeptidase A/*genetics, Renin-Angiotensin System/*genetics, Methionine, Sex Factors, Optic Neuropathy, Ischemic/*genetics, Confidence Intervals, DNA Transposable Elements, Odds Ratio, Humans, Female, Genetic Predisposition to Disease, Cysteine, Angiotensinogen/*genetics, Alleles, Gene Deletion, Aged
الوصول الحر: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::397c7c2bc8b55fe01b0672c8d4c7ed6cTest
http://olympias.lib.uoi.gr/jspui/handle/123456789/18664Test